Cytolethal distending toxin-induced cell cycle arrest of lymphocytes is dependent upon recognition and binding to cholesterol

Journal of Biological Chemistry

Volumn 284, Issue 16, 2009, Pages 10650-10658

  Boesze Battaglia, Kathleen ^a   Brown, Angela ^a   Walker, Lisa ^a   Besack, Dave ^a   Zekavat, Ali ^a   Wrenn, Steve ^b   Krummenacher, Claude ^a   Shenker, Bruce J ^a  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b Drexel University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE TOXINS; CELL-CYCLE ARREST; CONCENTRATION OF; FLUORESCENCE RESONANCE ENERGY TRANSFER; INTRACELLULAR TRANSFER; JURKAT CELL; LANOSTEROL; LIPID MEMBRANES; MEMBRANE CHOLESTEROL; MODEL MEMBRANES; PLASMA MEMBRANES; REDUCED TOXICITY; TOXIN BINDING;

AMINES; AMINO ACIDS; ASSOCIATION REACTIONS; BINDING ENERGY; BINDING SITES; CHOLESTEROL; ENERGY TRANSFER; FLUORESCENCE; MEMBRANES; ORGANIC ACIDS; SURFACE PLASMON RESONANCE; TOXIC MATERIALS;

CELL MEMBRANES;

CYTOLETHAL DISTENDING TOXIN; ERGOSTEROL; LANOSTEROL; STIGMASTEROL; BACTERIAL TOXIN; CHOLESTEROL; LIPOSOME;

AMINO ACID SEQUENCE; ARTICLE; ARTIFICIAL MEMBRANE; BINDING AFFINITY; BINDING SITE; CELL CYCLE ARREST; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE MUTATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIPID MEMBRANE; LYMPHOCYTE; MEMBRANE BINDING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE; ANIMAL; CELL CYCLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; METABOLISM; MUTATION;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL TOXINS; CELL CYCLE; CELL MEMBRANE; CHOLESTEROL; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; JURKAT CELLS; LIPOSOMES; LYMPHOCYTES; MEMBRANE MICRODOMAINS; MODELS, MOLECULAR; MUTATION; SURFACE PLASMON RESONANCE;

EID: 67449090254     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M809094200     Document Type: Article

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