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Volumn 100, Issue 4, 2009, Pages 671-677

Characterization of immunoglobulin heavy and light chain gene expression in chronic lymphocytic leukemia and related disorders

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; CCND1 PROTEIN, HUMAN; CD19 ANTIGEN; CD5 ANTIGEN; CYCLIN D1; IMMUNOGLOBULIN E RECEPTOR;

EID: 67449086643     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2009.01092.x     Document Type: Article
Times cited : (12)

References (41)
  • 2
    • 0014475016 scopus 로고
    • Relative frequency and mortality rate of various types of leukemia in Japan
    • Nishiyama H, Mokuno J, Inoue T. Relative frequency and mortality rate of various types of leukemia in Japan. Gann. 1969; 60: 71-81.
    • (1969) Gann , vol.60 , pp. 71-81
    • Nishiyama, H.1    Mokuno, J.2    Inoue, T.3
  • 3
    • 0018563913 scopus 로고
    • Geographical variation in the incidence of the leukemias and lymphomas
    • Weiss NS. Geographical variation in the incidence of the leukemias and lymphomas. Natl Cancer Inst Monogr. 1979; 53: 139-42.
    • (1979) Natl Cancer Inst Monogr , vol.53 , pp. 139-142
    • Weiss, N.S.1
  • 4
    • 17944371759 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia (CLL) is rare, but the proportion of T-CLL is high in Japan
    • Tamura K, Sawada H, Izumi Y et al. Chronic lymphocytic leukemia (CLL) is rare, but the proportion of T-CLL is high in Japan. Eur J Haematol. 2001; 67: 152-7.
    • (2001) Eur J Haematol , vol.67 , pp. 152-157
    • Tamura, K.1    Sawada, H.2    Izumi, Y.3
  • 6
    • 0033567968 scopus 로고    scopus 로고
    • IgV gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle RN, Wasil T, Fais F et al. IgV gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood. 1999; 94: 1840-7.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3
  • 7
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated IgV(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated IgV(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 1999; 94: 1848-54.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 8
    • 0032532668 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors
    • Fais F, Ghiotto F, Hashimoto S et al. Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors. J Clin Invest. 1998; 102: 1515-25.
    • (1998) J Clin Invest , vol.102 , pp. 1515-1525
    • Fais, F.1    Ghiotto, F.2    Hashimoto, S.3
  • 9
    • 0042971643 scopus 로고    scopus 로고
    • B cell chronic lymphocytic leukemia: Lessons learned from studies of the B cell antigen receptor
    • Chiorazzi N, Ferrarini M. B cell chronic lymphocytic leukemia: Lessons learned from studies of the B cell antigen receptor. Annu Rev Immunol. 2003; 21: 841-94.
    • (2003) Annu Rev Immunol , vol.21 , pp. 841-894
    • Chiorazzi, N.1    Ferrarini, M.2
  • 10
    • 0030639650 scopus 로고    scopus 로고
    • Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features
    • Johnson TA, Rassenti LZ, Kipps TJ. Ig VH1 genes expressed in B cell chronic lymphocytic leukemia exhibit distinctive molecular features. J Immunol. 1997; 158: 235-46.
    • (1997) J Immunol , vol.158 , pp. 235-246
    • Johnson, T.A.1    Rassenti, L.Z.2    Kipps, T.J.3
  • 11
    • 0028355650 scopus 로고
    • The pathogenesis of chronic lymphocytic leukemia: Analysis of the antibody repertoire
    • Schroeder HW Jr, Dighiero G. The pathogenesis of chronic lymphocytic leukemia: Analysis of the antibody repertoire. Immunol Today. 1994; 15: 288-94.
    • (1994) Immunol Today , vol.15 , pp. 288-294
    • Schroeder Jr., H.W.1    Dighiero, G.2
  • 12
    • 10744230550 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: Implicating recognition of a common antigen epitope
    • Tobin G, Thunberg U, Johnson A et al. Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: Implicating recognition of a common antigen epitope. Blood. 2003; 101: 4952-7.
    • (2003) Blood , vol.101 , pp. 4952-4957
    • Tobin, G.1    Thunberg, U.2    Johnson, A.3
  • 13
    • 4944244255 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins
    • Widhopf GF, Rassenti LZ 2nd, Toy TL, Gribben JG, Wierda WG, Kipps TJ. Chronic lymphocytic leukemia B cells of more than 1% of patients express virtually identical immunoglobulins. Blood. 2004; 104: 2499-504.
    • (2004) Blood , vol.104 , pp. 2499-2504
    • Widhopf, G.F.1    Rassenti II, L.Z.2    Toy, T.L.3    Gribben, J.G.4    Wierda, W.G.5    Kipps, T.J.6
  • 14
    • 38949203770 scopus 로고    scopus 로고
    • Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: Implications for the role of antigen selection in leukemogenesis
    • Murray F, Darzentas N, Hadzidimitriou A et al. Stereotyped patterns of somatic hypermutation in subsets of patients with chronic lymphocytic leukemia: Implications for the role of antigen selection in leukemogenesis. Blood. 2008; 111: 1524-33.
    • (2008) Blood , vol.111 , pp. 1524-1533
    • Murray, F.1    Darzentas, N.2    Hadzidimitriou, A.3
  • 15
    • 11144356992 scopus 로고    scopus 로고
    • Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia
    • Ghiotto F. Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia. J Clin Invest. 2004; 113: 1008-16.
    • (2004) J Clin Invest , vol.113 , pp. 1008-1016
    • Ghiotto, F.1
  • 16
    • 33846108722 scopus 로고    scopus 로고
    • Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations
    • Stamatopoulos K, Belessi C, Moreno C et al. Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations. Blood. 2007; 109: 259-70.
    • (2007) Blood , vol.109 , pp. 259-270
    • Stamatopoulos, K.1    Belessi, C.2    Moreno, C.3
  • 17
    • 4344704897 scopus 로고    scopus 로고
    • Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia
    • Messmer BT, Albesiano E, Efremov DG et al. Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia. J Exp Med. 2004; 200: 519-25.
    • (2004) J Exp Med , vol.200 , pp. 519-525
    • Messmer, B.T.1    Albesiano, E.2    Efremov, D.G.3
  • 18
    • 30144431925 scopus 로고    scopus 로고
    • Distinctive immunoglobulin VH gene usage in Japanese patients with chronic lymphocytic leukemia
    • Koiso H, Yamane A, Mitsui T et al. Distinctive immunoglobulin VH gene usage in Japanese patients with chronic lymphocytic leukemia. Leuk Res. 2006; 30: 272-6.
    • (2006) Leuk Res , vol.30 , pp. 272-276
    • Koiso, H.1    Yamane, A.2    Mitsui, T.3
  • 19
    • 0000634555 scopus 로고
    • Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia
    • Kipps TJ, Tomhave E, Pratt LF, Duffy S, Chen PP, Carson DA. Developmentally restricted immunoglobulin heavy chain variable region gene expressed at high frequency in chronic lymphocytic leukemia. Proc Natl Acad Sci USA. 1989; 86: 5913-17.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 5913-5917
    • Kipps, T.J.1    Tomhave, E.2    Pratt, L.F.3    Duffy, S.4    Chen, P.P.5    Carson, D.A.6
  • 20
    • 27744598787 scopus 로고    scopus 로고
    • Immunoglobulin light chain repertoire in chronic lymphocytic leukemia
    • Stamatopoulos K, Belessi C, Hadzidimitriou A et al. Immunoglobulin light chain repertoire in chronic lymphocytic leukemia. Blood. 2005; 106: 3575-83.
    • (2005) Blood , vol.106 , pp. 3575-3583
    • Stamatopoulos, K.1    Belessi, C.2    Hadzidimitriou, A.3
  • 21
    • 33947644251 scopus 로고    scopus 로고
    • Similarities and differences between the light and heavy chain Ig variable region gene repertoires in chronic lymphocytic leukemia
    • Ghiotto F, Fais F, Albesiano E et al. Similarities and differences between the light and heavy chain Ig variable region gene repertoires in chronic lymphocytic leukemia. Mol Med. 2006; 12: 300-8.
    • (2006) Mol Med , vol.12 , pp. 300-308
    • Ghiotto, F.1    Fais, F.2    Albesiano, E.3
  • 22
    • 43749107921 scopus 로고    scopus 로고
    • V lambda genes in chronic lymphocytic leukemia: Highly skewed V gene segment usage with similar CDR3 sequences
    • Abusedra A, Joshi R, Bybee A, Apperley JF, Wagner SD. V lambda genes in chronic lymphocytic leukemia: Highly skewed V gene segment usage with similar CDR3 sequences. Leukemia. 2008; 22: 1073-5.
    • (2008) Leukemia , vol.22 , pp. 1073-1075
    • Abusedra, A.1    Joshi, R.2    Bybee, A.3    Apperley, J.F.4    Wagner, S.D.5
  • 23
    • 42449120194 scopus 로고    scopus 로고
    • Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3
    • Widhopf GF, Goldberg CJ 2nd, Toy TL et al. Nonstochastic pairing of immunoglobulin heavy and light chains expressed by chronic lymphocytic leukemia B cells is predicated on the heavy chain CDR3. Blood. 2008; 111: 3137-44.
    • (2008) Blood , vol.111 , pp. 3137-3144
    • Widhopf, G.F.1    Goldberg II, C.J.2    Toy, T.L.3
  • 24
    • 0036458938 scopus 로고    scopus 로고
    • The naive T-lymphocyte compartment is well preserved in patients with chronic myelogenous leukaemia in chronic phase
    • Isoda A, Yokohama A, Matsushima T, Tsukamoto N, Nojima Y, Karasawa M. The naive T-lymphocyte compartment is well preserved in patients with chronic myelogenous leukaemia in chronic phase. Br J Haematol. 2002; 119: 949-55.
    • (2002) Br J Haematol , vol.119 , pp. 949-955
    • Isoda, A.1    Yokohama, A.2    Matsushima, T.3    Tsukamoto, N.4    Nojima, Y.5    Karasawa, M.6
  • 25
    • 0027753103 scopus 로고
    • Detection of clonal B-cell populations in paraffin-embedded tissues by polymerase chain reaction
    • Küppers R, Willenbrock K, Rajewsky K, Hansmann ML. Detection of clonal B-cell populations in paraffin-embedded tissues by polymerase chain reaction. Am J Pathol. 1993; 44: 230-9.
    • (1993) Am J Pathol , vol.44 , pp. 230-239
    • Küppers, R.1    Willenbrock, K.2    Rajewsky, K.3    Hansmann, M.L.4
  • 26
    • 9144265458 scopus 로고    scopus 로고
    • Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 concerted action BMH4-CT98-3936
    • van Dongen JJ, Langerak AW, Brüggemann M et al. Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 concerted action BMH4-CT98-3936. Leukemia. 2003; 17: 2257-317.
    • (2003) Leukemia , vol.17 , pp. 2257-2317
    • van Dongen, J.J.1    Langerak, A.W.2    Brüggemann, M.3
  • 27
    • 24944511686 scopus 로고    scopus 로고
    • The international familial CLL consortium
    • Marti GE, Rawstron AC, Ghia P et al. The international familial CLL consortium. Diagnostic criteria for monoclonal B-cell lymphocytosis. Br J Haematol. 2005; 130: 325-32.
    • (2005) Br J Haematol , vol.130 , pp. 325-332
    • Marti, G.E.1    Rawstron, A.C.2    Ghia, P.3
  • 28
    • 0036063717 scopus 로고    scopus 로고
    • Quantitative analysis of Cyclin D1 and CD23 expression in mantle cell lymphoma and B-chronic lymphocytic leukemia
    • Koiso H, Tsukamoto N, Miyawaki S, Shinonome S, Nojima Y, Karasawa M. Quantitative analysis of Cyclin D1 and CD23 expression in mantle cell lymphoma and B-chronic lymphocytic leukemia. Leuk Res. 2002; 26: 809-15.
    • (2002) Leuk Res , vol.26 , pp. 809-815
    • Koiso, H.1    Tsukamoto, N.2    Miyawaki, S.3    Shinonome, S.4    Nojima, Y.5    Karasawa, M.6
  • 29
    • 33845513520 scopus 로고    scopus 로고
    • ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia
    • Ghia P, Stamatopoulos K, Belessi C et al. ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia. Leukemia. 2007; 21: 1-3.
    • (2007) Leukemia , vol.21 , pp. 1-3
    • Ghia, P.1    Stamatopoulos, K.2    Belessi, C.3
  • 30
    • 0028328795 scopus 로고
    • Surface phenotype and Ig heavy-chain gene usage in chronic B-cell leukemias: Expression of myelomonocytic surface markers in CD5-chronic B-cell leukemia
    • Ikematsu W, Ikematsu H, Okamura S, Otsuka T, Harada M, Niho Y. Surface phenotype and Ig heavy-chain gene usage in chronic B-cell leukemias: expression of myelomonocytic surface markers in CD5-chronic B-cell leukemia. Blood. 1994; 83: 2602-10.
    • (1994) Blood , vol.83 , pp. 2602-2610
    • Ikematsu, W.1    Ikematsu, H.2    Okamura, S.3    Otsuka, T.4    Harada, M.5    Niho, Y.6
  • 31
    • 0032824069 scopus 로고    scopus 로고
    • Analysis of the immunoglobulin heavy chain gene variable region of 101 cases with peripheral B cell neoplasms and B cell chronic lymphocytic leukemia in the Japanese population
    • Nakamura N, Kuze T, Hashimoto Y et al. Analysis of the immunoglobulin heavy chain gene variable region of 101 cases with peripheral B cell neoplasms and B cell chronic lymphocytic leukemia in the Japanese population. Pathol Int. 1999; 49: 595-600.
    • (1999) Pathol Int , vol.49 , pp. 595-600
    • Nakamura, N.1    Kuze, T.2    Hashimoto, Y.3
  • 32
    • 34247213391 scopus 로고    scopus 로고
    • Analysis of the immunoglobulin heavy chain variable region gene expression in Iranian patients with chronic lymphocytic leukemia
    • Farsangi MH, Jeddi-Tehrani M, Sharifian RA et al. Analysis of the immunoglobulin heavy chain variable region gene expression in Iranian patients with chronic lymphocytic leukemia. Leuk Lymphoma. 2007; 48: 109-16.
    • (2007) Leuk Lymphoma , vol.48 , pp. 109-116
    • Farsangi, M.H.1    Jeddi-Tehrani, M.2    Sharifian, R.A.3
  • 33
    • 44749086562 scopus 로고    scopus 로고
    • Distinctive IgVH gene segments usage and mutation status in Chinese patients with chronic lymphocytic leukemia
    • Chen L, Zhang Y, Zheng W et al. Distinctive IgVH gene segments usage and mutation status in Chinese patients with chronic lymphocytic leukemia. Leuk Res. 2008; 32: 1491-1498.
    • (2008) Leuk Res , vol.32 , pp. 1491-1498
    • Chen, L.1    Zhang, Y.2    Zheng, W.3
  • 34
    • 0034789991 scopus 로고    scopus 로고
    • Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance
    • Pugh-Bernard AE, Silverman GJ, Cappione AJ et al. Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell tolerance. J Clin Invest. 2001; 108: 1061-70.
    • (2001) J Clin Invest , vol.108 , pp. 1061-1070
    • Pugh-Bernard, A.E.1    Silverman, G.J.2    Cappione, A.J.3
  • 35
    • 0029664523 scopus 로고    scopus 로고
    • VH gene usage is multiple myeloma: Complete absence of the VH4.21 (VH4-34) gene
    • Rettig MB, Vescio RA, Cao J et al. VH gene usage is multiple myeloma: complete absence of the VH4.21 (VH4-34) gene. Blood. 1996; 87: 2846-52.
    • (1996) Blood , vol.87 , pp. 2846-2852
    • Rettig, M.B.1    Vescio, R.A.2    Cao, J.3
  • 36
    • 0030985603 scopus 로고    scopus 로고
    • Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells
    • Foster SJ, Brezinschek HP, Brezinschek RI, Lipsky PE. Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells. J Clin Invest. 1997; 99: 1614-27.
    • (1997) J Clin Invest , vol.99 , pp. 1614-1627
    • Foster, S.J.1    Brezinschek, H.P.2    Brezinschek, R.I.3    Lipsky, P.E.4
  • 37
    • 0031586002 scopus 로고    scopus 로고
    • The creation of diversity in the human immunoglobulin V (lambda) repertoire
    • Ignatovich O, Tomlinson IM, Jones PT, Winter G. The creation of diversity in the human immunoglobulin V (lambda) repertoire. J Mol Biol. 1997; 268: 69-77.
    • (1997) J Mol Biol , vol.268 , pp. 69-77
    • Ignatovich, O.1    Tomlinson, I.M.2    Jones, P.T.3    Winter, G.4
  • 38
    • 0033593356 scopus 로고    scopus 로고
    • Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire
    • de Wildt RM, Hoet RM, van Venrooij WJ, Tomlinson IM, Winter G. Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire. J Mol Biol. 1999; 285: 895-901.
    • (1999) J Mol Biol , vol.285 , pp. 895-901
    • de Wildt, R.M.1    Hoet, R.M.2    van Venrooij, W.J.3    Tomlinson, I.M.4    Winter, G.5
  • 39
    • 33845189398 scopus 로고    scopus 로고
    • V(H)348 and V(H)353, as well as V(H)321, gene rearrangements define unique subgroups in CLL and are associated with biased lambda light chain restriction, homologous LCDR3 sequences and poor prognosis
    • Matthews C, Catherwood MA, Morris TC, Alexander HD. V(H)348 and V(H)353, as well as V(H)321, gene rearrangements define unique subgroups in CLL and are associated with biased lambda light chain restriction, homologous LCDR3 sequences and poor prognosis. Leuk Res. 2007; 31: 231-4.
    • (2007) Leuk Res , vol.31 , pp. 231-234
    • Matthews, C.1    Catherwood, M.A.2    Morris, T.C.3    Alexander, H.D.4
  • 40
    • 20444454585 scopus 로고    scopus 로고
    • Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity
    • HervéM, Xu K, Ng YS et al. Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity. J Clin Invest. 2005; 115: 1636-43.
    • (2005) J Clin Invest , vol.115 , pp. 1636-1643
    • Hervé, M.1    Xu, K.2    Ng, Y.S.3
  • 41
    • 46749099871 scopus 로고    scopus 로고
    • Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection
    • Ghia EM, Jain S, Widhopf GF 2nd et al. Use of IGHV3-21 in chronic lymphocytic leukemia is associated with high-risk disease and reflects antigen-driven, post-germinal center leukemogenic selection. Blood. 2008; 111: 5101-8.
    • (2008) Blood , vol.111 , pp. 5101-5108
    • Ghia, E.M.1    Jain, S.2    Widhopf II, G.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.