Serum from Radiofrequency-Injured Livers Induces Differentiation of Bone Marrow Stem Cells into Hepatocyte-Like Cells

Journal of Surgical Research

Volumn 155, Issue 1, 2009, Pages 18-24

  Yang, Yi ^a   Qu, Bo ^a   Huo, Jian Hua ^a   Wu, Sheng Li ^a   Zhang, Ming Yu ^b   Wang, Zuo Ren ^a  

^a First Affiliated Hospital   (China)

^b the Second Affiliated Hospital   (China)

Author keywords

bone marrow stem cells; hepatic injury; hepatocyte like cells; radiofrequency ablation

Indexed keywords

ALBUMIN; CELL MARKER; SCATTER FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL DIFFERENTIATION; CELL ISOLATION; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; CULTURE MEDIUM; FETAL CALF SERUM; HEMATOPOIETIC STEM CELL; LIVER CELL; LIVER INJURY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RABBIT; RADIOFREQUENCY ABLATION; SERUM;

ANIMALS; BLOOD TRANSFUSION, AUTOLOGOUS; BONE MARROW CELLS; CATHETER ABLATION; CELL CYCLE; CELL DIFFERENTIATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HEPATOCYTES; LIVER NEOPLASMS; LIVER REGENERATION; RABBITS;

EID: 67349285105     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2009.01.006     Document Type: Article

References (19)

1. Petersen B.E., Bowen W.C., Patrene K.D., et al. Bone marrow as a potential source of hepatic oval cells. Science 284 (1999) 1168
2. Sharma A.D., Cantz T., Manns M.P., et al. The role of stem cells in physiology, pathophysiology, and therapy of the liver. Stem Cell Rev 2 (2006) 51
3. Am Esch II J.S., Knoefel W.T., Klein M., et al. Portal application of autologous CD133+ bone marrow cells to the liver: A novel concept to support hepatic regeneration. Stem Cells 23 (2005) 463
4. Merkle E.M., Boll D.T., Boaz T., et al. MRI-guided radiofrequency thermal ablation of implanted VX2 liver tumors in a rabbit model: Demonstration of feasibility at 0.2 T. Magn Reson Med 42 (1999) 141
5. Lin S.M., Lin C.J., Lin C.C., et al. Randomized controlled trial comparing percutaneous radiofrequency thermal ablation, percutaneous ethanol injection, and percutaneous acetic acid injection to treat hepatocellular carcinoma of 3 cm or less. Gut 54 (2005) 1151
6. Fang D., Seo B.M., Liu Y., et al. Transplantation of mesenchymal stem cells is an optimal approach for plastic surgery. Stem Cells 25 (2007) 1021
7. Mizuno N., Shiba H., Ozeki Y., et al. Human autologous serum obtained using a completely closed bag system as a substitute for fetal calf serum in human mesenchymal stem cell cultures. Cell Biol Int 30 (2006) 521
8. Bruinink A., Tobler U., Halg M., et al. Effects of serum and serum heat-inactivation on human bone derived osteoblast progenitor cells. J Mater Sci Mater Med 15 (2004) 497
9. Qihao Z., Xigu C., Guanghui C., et al. Spheroid formation and differentiation into hepatocyte-like cells of rat mesenchymal stem cell induced by co-culture with liver cells. DNA Cell Biol 26 (2007) 497
10. Bhowmick N.A., Chytil A., Plieth D., et al. TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science 303 (2004) 848
11. Forte G., Minieri M., Cossa P., et al. Hepatocyte growth factor effects on mesenchymal stem cells: Proliferation, migration, and differentiation. Stem Cells 24 (2006) 23
12. Neuss S., Becher E., Woltje M., et al. Functional expression of HGF and HGF receptor/c-met in adult human mesenchymal stem cells suggests a role in cell mobilization, tissue repair, and wound healing. Stem Cells 22 (2004) 405
13. Hatch H.M., Zheng D., Jorgensen M.L., et al. SDF-1alpha/CXCR4: A mechanism for hepatic oval cell activation and bone marrow stem cell recruitment to the injured liver of rats. Cloning Stem Cells 4 (2002) 339
14. Tang L.J., Gao Y., Zhang Z., et al. [Human bone marrow multipotent adult progenitor cells differentiate into hepatocyte-like cells with hepatocyte growth factor plus fibroblast growth factor-4 in vitro]. Zhonghua Gan Zang Bing Za Zhi 13 (2005) 652
15. Theise N.D., Nimmakayalu M., Gardner R., et al. Liver from bone marrow in humans. Hepatology 32 (2000) 11
16. Theise N.D., Badve S., Saxena R., et al. Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation. Hepatology 31 (2000) 235
17. Am Esch II J.S., Knoefel W.T., Klein M., et al. Portal application of autologous CD133+ bone marrow cells to the liver: A novel concept to support hepatic regeneration. Stem Cells 23 (2005) 463
18. Mitchell C., and Fausto N. Bone marrow - derived hepatocytes: Rare but promising. Am J Pathol 161 (2002) 349
19. Pawliuk R., Westerman K.A., Fabry M.E., et al. Correction of sickle cell disease in transgenic mouse models by gene therapy. Science 294 (2001) 2368