-
1
-
-
0035668921
-
Structural biology of human follitropin and its receptor
-
Dias, J.A., Van Roey, P., Structural biology of human follitropin and its receptor. Arch. Med. Res. 32 (2001), 510–519.
-
(2001)
Arch. Med. Res.
, vol.32
, pp. 510-519
-
-
Dias, J.A.1
Van Roey, P.2
-
2
-
-
0028239813
-
Crystal structure of human chorionic gonadotropin
-
Lapthorn, A.J., Harris, D.C., Littlejohn, A., et al. Crystal structure of human chorionic gonadotropin. Nature 369 (1994), 455–461.
-
(1994)
Nature
, vol.369
, pp. 455-461
-
-
Lapthorn, A.J.1
Harris, D.C.2
Littlejohn, A.3
-
3
-
-
0027158153
-
The lutropin/choriogonadotropin receptor… 4 years later
-
Segaloff, D.L., Ascoli, M., The lutropin/choriogonadotropin receptor… 4 years later. Endocr. Rev. 14 (1993), 324–347.
-
(1993)
Endocr. Rev.
, vol.14
, pp. 324-347
-
-
Segaloff, D.L.1
Ascoli, M.2
-
4
-
-
0026743033
-
The thyrotropin receptor and the regulation of thyrocyte function and growth
-
Vassart, G., Dumont, J.E., The thyrotropin receptor and the regulation of thyrocyte function and growth. Endocr. Rev. 13 (1992), 596–611.
-
(1992)
Endocr. Rev.
, vol.13
, pp. 596-611
-
-
Vassart, G.1
Dumont, J.E.2
-
5
-
-
0002817709
-
The thyrotropin receptor and the regulation of thyrocyte function and growth: update 1994
-
Vassart, G., Parma, J., Van Sande, J., Dumont, J., The thyrotropin receptor and the regulation of thyrocyte function and growth: update 1994. Endocr. Rev. 3 (1994), 77–80.
-
(1994)
Endocr. Rev.
, vol.3
, pp. 77-80
-
-
Vassart, G.1
Parma, J.2
Van Sande, J.3
Dumont, J.4
-
6
-
-
0032247323
-
The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies
-
(In Process Citation)
-
Rapoport, B., Chazenbalk, G.D., Jaume, J.C., McLachlan, S.M., The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies. Endocr. Rev. 19 (1998), 673–716 (In Process Citation).
-
(1998)
Endocr. Rev.
, vol.19
, pp. 673-716
-
-
Rapoport, B.1
Chazenbalk, G.D.2
Jaume, J.C.3
McLachlan, S.M.4
-
7
-
-
0028911034
-
A structural basis of the interactions between leucine-rich repeats and protein ligands
-
Kobe, B., Deisenhofer, J., A structural basis of the interactions between leucine-rich repeats and protein ligands. Nature 374 (1995), 183–186.
-
(1995)
Nature
, vol.374
, pp. 183-186
-
-
Kobe, B.1
Deisenhofer, J.2
-
8
-
-
0027718173
-
Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats
-
Kobe, B., Deisenhofer, J., Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats. Nature 366 (1993), 751–756.
-
(1993)
Nature
, vol.366
, pp. 751-756
-
-
Kobe, B.1
Deisenhofer, J.2
-
9
-
-
0029645408
-
Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats
-
Kajava, A.V., Vassart, G., Wodak, S.J., Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats. Structure 3 (1995), 867–877.
-
(1995)
Structure
, vol.3
, pp. 867-877
-
-
Kajava, A.V.1
Vassart, G.2
Wodak, S.J.3
-
10
-
-
0029757509
-
Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling
-
Bhowmick, N., Huang, J., Puett, D., Isaacs, N.W., Lapthorn, A.J., Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling. Mol. Endocrinol. 10 (1996), 1147–1159.
-
(1996)
Mol. Endocrinol.
, vol.10
, pp. 1147-1159
-
-
Bhowmick, N.1
Huang, J.2
Puett, D.3
Isaacs, N.W.4
Lapthorn, A.J.5
-
11
-
-
0037084011
-
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors
-
Costagliola, S., Panneels, V., Bonomi, M., et al. Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors. EMBO J. 21 (2002), 504–513.
-
(2002)
EMBO J.
, vol.21
, pp. 504-513
-
-
Costagliola, S.1
Panneels, V.2
Bonomi, M.3
-
12
-
-
0027369421
-
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
-
Parma, J., Duprez, L., Van Sande, J., et al. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature 365 (1993), 649–651.
-
(1993)
Nature
, vol.365
, pp. 649-651
-
-
Parma, J.1
Duprez, L.2
Van Sande, J.3
-
13
-
-
0026464910
-
Mutation of alanine 623 in the third cytoplasmic loop of the rat TSH receptor results in a loss in the phosphoinositide but not cAMP signal induced by TSH and receptor autoantibodies
-
Kosugi, S., Okajima, F., Ban, T., Hidaka, A., Shenker, A., Kohn, L., Mutation of alanine 623 in the third cytoplasmic loop of the rat TSH receptor results in a loss in the phosphoinositide but not cAMP signal induced by TSH and receptor autoantibodies. J. Biol. Chem. 267 (1992), 24153–24156.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 24153-24156
-
-
Kosugi, S.1
Okajima, F.2
Ban, T.3
Hidaka, A.4
Shenker, A.5
Kohn, L.6
-
14
-
-
0001148781
-
Thyroid Disorders
-
C.R. Scriver 8th ed. McGraw-Hill New York
-
Refetoff, S., Dumont, J.E., Vassart, G., Thyroid Disorders. Scriver, C.R., (eds.) The Metabolic and Molecular Bases of Inherited Diseases, 8th ed., 2001, McGraw-Hill, New York, 4029–4076.
-
(2001)
The Metabolic and Molecular Bases of Inherited Diseases
, pp. 4029-4076
-
-
Refetoff, S.1
Dumont, J.E.2
Vassart, G.3
-
15
-
-
0033711033
-
Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function
-
Themmen, A.P.N., Huhtaniemi, I.T., Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function. Endocr. Rev. 21 (2000), 551–583.
-
(2000)
Endocr. Rev.
, vol.21
, pp. 551-583
-
-
Themmen, A.P.N.1
Huhtaniemi, I.T.2
-
16
-
-
0029832901
-
Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop
-
Kudo, M., Osuga, Y., Kobilka, B.K., Hsueh, A.J., Transmembrane regions V and VI of the human luteinizing hormone receptor are required for constitutive activation by a mutation in the third intracellular loop. J. Biol. Chem. 271 (1996), 22470–22478.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22470-22478
-
-
Kudo, M.1
Osuga, Y.2
Kobilka, B.K.3
Hsueh, A.J.4
-
17
-
-
0037165664
-
A conserved Asn in TM7 of the TSH receptor is a common requirement for activation by both mutations and its natural agonist
-
Claeysen, S., Govaerts, C., Lefort, A., et al. A conserved Asn in TM7 of the TSH receptor is a common requirement for activation by both mutations and its natural agonist. FEBS Lett. 517 (2002), 195–200.
-
(2002)
FEBS Lett.
, vol.517
, pp. 195-200
-
-
Claeysen, S.1
Govaerts, C.2
Lefort, A.3
-
18
-
-
85023135859
-
A conserved ASN in TM7 is a on/off switch in the activation of the TSH receptor
-
Govaerts, C., Lefort, A., Costagliola, S., et al. A conserved ASN in TM7 is a on/off switch in the activation of the TSH receptor. J. Biol. Chem., 2001.
-
(2001)
J. Biol. Chem.
-
-
Govaerts, C.1
Lefort, A.2
Costagliola, S.3
-
19
-
-
0032881333
-
The hypothyroidism in an inbred kindred with congenital thyroid hormone and glucocorticoid deficiency is due to a mutation producing a truncated thyrotropin receptor
-
Tiosano, D., Pannain, S., Vassart, G., et al. The hypothyroidism in an inbred kindred with congenital thyroid hormone and glucocorticoid deficiency is due to a mutation producing a truncated thyrotropin receptor. Thyroid 9 (1999), 887–894.
-
(1999)
Thyroid
, vol.9
, pp. 887-894
-
-
Tiosano, D.1
Pannain, S.2
Vassart, G.3
-
20
-
-
8544221172
-
Diversity and prevalence of somatic mutations in the TSH receptor and Gs alpha genes as a cause of toxic thyroid adenomas
-
Parma, J., Duprez, L., Van Sande, J., Hermans, J., Van Vliet, G., Costagliola, S., Rodien, P., Dumont, J.E., Vassart, G., Diversity and prevalence of somatic mutations in the TSH receptor and Gs alpha genes as a cause of toxic thyroid adenomas. J. Clin. Endocrinol. Metab. 82 (1997), 2695–2701.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 2695-2701
-
-
Parma, J.1
Duprez, L.2
Van Sande, J.3
Hermans, J.4
Van Vliet, G.5
Costagliola, S.6
Rodien, P.7
Dumont, J.E.8
Vassart, G.9
-
21
-
-
0029888302
-
Specific activation of the thyrotropin receptor by trypsin
-
Van Sande, J., Massart, C., Costagliola, S., et al. Specific activation of the thyrotropin receptor by trypsin. Mol. Cell. Endocrinol. 119 (1996), 161–168.
-
(1996)
Mol. Cell. Endocrinol.
, vol.119
, pp. 161-168
-
-
Van Sande, J.1
Massart, C.2
Costagliola, S.3
-
22
-
-
0036214718
-
Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist
-
Vlaeminck, V., Ho, S.C., Rodien, P., Vassart, G., Costagliola, S., Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist. Mol. Endocrinol. 16 (2002), 736–746.
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 736-746
-
-
Vlaeminck, V.1
Ho, S.C.2
Rodien, P.3
Vassart, G.4
Costagliola, S.5
-
23
-
-
0034457935
-
The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone–receptor interaction and antagonist design
-
Zhang, M., Tong, K.P., Fremont, V., et al. The extracellular domain suppresses constitutive activity of the transmembrane domain of the human TSH receptor: implications for hormone–receptor interaction and antagonist design. Endocrinology 141 (2000), 3514–3517.
-
(2000)
Endocrinology
, vol.141
, pp. 3514-3517
-
-
Zhang, M.1
Tong, K.P.2
Fremont, V.3
-
24
-
-
0034464742
-
Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
-
Gether, U., Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr. Rev. 21 (2000), 90–113.
-
(2000)
Endocr. Rev.
, vol.21
, pp. 90-113
-
-
Gether, U.1
-
25
-
-
0027513982
-
A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model
-
Samama, P., Cotecchia, S., Costa, T., Lefkowitz, R.J., A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model. J. Biol. Chem. 268 (1993), 4625–4636.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 4625-4636
-
-
Samama, P.1
Cotecchia, S.2
Costa, T.3
Lefkowitz, R.J.4
-
26
-
-
0025739241
-
Human choriogonadotrophin binds to a lutropin receptor with essentially no N-terminal extension and stimulates cAMP synthesis
-
Ji, I., Ji, T., Human choriogonadotrophin binds to a lutropin receptor with essentially no N-terminal extension and stimulates cAMP synthesis. J. Biol. Chem. 266 (1991), 1306–1309.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 1306-1309
-
-
Ji, I.1
Ji, T.2
-
27
-
-
0037040202
-
The ectodomain of the luteinizing hormone receptor interacts with exoloop 2 to constraint the transmembrane region: studies using chimeric human and fly receptors
-
Nishi, S., Nakabayashi, K., Kobilka, B., Hsueh, A.J., The ectodomain of the luteinizing hormone receptor interacts with exoloop 2 to constraint the transmembrane region: studies using chimeric human and fly receptors. J. Biol. Chem. 277 (2002), 3958–3964.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3958-3964
-
-
Nishi, S.1
Nakabayashi, K.2
Kobilka, B.3
Hsueh, A.J.4
-
28
-
-
0030805829
-
Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain
-
Duprez, L., Parma, J., Costagliola, S., et al. Constitutive activation of the TSH receptor by spontaneous mutations affecting the N-terminal extracellular domain. FEBS Lett. 409 (1997), 469–474.
-
(1997)
FEBS Lett.
, vol.409
, pp. 469-474
-
-
Duprez, L.1
Parma, J.2
Costagliola, S.3
-
29
-
-
0034730516
-
Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region
-
Nakabayashi, K., Kudo, M., Kobilka, B., Hsueh, A.J., Activation of the luteinizing hormone receptor following substitution of Ser-277 with selective hydrophobic residues in the ectodomain hinge region. J. Biol. Chem. 275 (2000), 30264–30271.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30264-30271
-
-
Nakabayashi, K.1
Kudo, M.2
Kobilka, B.3
Hsueh, A.J.4
-
30
-
-
0034987731
-
Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity
-
Ho, S.C., Van Sande, J., Lefort, A., Vassart, G., Costagliola, S., Effects of mutations involving the highly conserved S281HCC motif in the extracellular domain of the thyrotropin (TSH) receptor on TSH binding and constitutive activity. Endocrinology 142 (2001), 2760–2767.
-
(2001)
Endocrinology
, vol.142
, pp. 2760-2767
-
-
Ho, S.C.1
Van Sande, J.2
Lefort, A.3
Vassart, G.4
Costagliola, S.5
|