-
1
-
-
34250025351
-
Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels
-
Rafiq S, Stevens K, Hurst AJ, Murray A, Henley W, Weedon MN et al. Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels. Genes Immun 2007; 8: 344-351.
-
(2007)
Genes Immun
, vol.8
, pp. 344-351
-
-
Rafiq, S.1
Stevens, K.2
Hurst, A.J.3
Murray, A.4
Henley, W.5
Weedon, M.N.6
-
2
-
-
0030961241
-
Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein
-
Gabay C, Smith MF, Eidlen D, Arend WP. Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein. J Clin Invest 1997; 99: 2930-2940.
-
(1997)
J Clin Invest
, vol.99
, pp. 2930-2940
-
-
Gabay, C.1
Smith, M.F.2
Eidlen, D.3
Arend, W.P.4
-
3
-
-
12444290860
-
Adipose tissue is a major source of interleukin-1 receptor antagonist: Upregulation in obesity and inflammation
-
Juge-Aubry CE, Somm E, Giusti V, Pernin A, Chicheportiche R, Verdumo C et al. Adipose tissue is a major source of interleukin-1 receptor antagonist: upregulation in obesity and inflammation. Diabetes 2003; 52: 1104-1110.
-
(2003)
Diabetes
, vol.52
, pp. 1104-1110
-
-
Juge-Aubry, C.E.1
Somm, E.2
Giusti, V.3
Pernin, A.4
Chicheportiche, R.5
Verdumo, C.6
-
4
-
-
31744452332
-
Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents
-
Somm E, Cettour-Rose P, Asensio C, Charollais A, Klein M, Theander-Carrillo C et al. Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents. Diabetologia 2006; 49: 387-393.
-
(2006)
Diabetologia
, vol.49
, pp. 387-393
-
-
Somm, E.1
Cettour-Rose, P.2
Asensio, C.3
Charollais, A.4
Klein, M.5
Theander-Carrillo, C.6
-
5
-
-
0036694645
-
The balance between IL-1 and IL-1Ra in disease
-
Arend WP. The balance between IL-1 and IL-1Ra in disease. Cytokine Growth Factor Rev 2002; 13: 323-340.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 323-340
-
-
Arend, W.P.1
-
6
-
-
0034618862
-
The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1
-
Dinarello CA. The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1. N Engl J Med 2000; 343: 732-734.
-
(2000)
N Engl J Med
, vol.343
, pp. 732-734
-
-
Dinarello, C.A.1
-
7
-
-
18644374105
-
Blocking IL-1 in systemic inflammation
-
Dinarello CA. Blocking IL-1 in systemic inflammation. J Exp Med 2005; 201: 1355-1359.
-
(2005)
J Exp Med
, vol.201
, pp. 1355-1359
-
-
Dinarello, C.A.1
-
8
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
Larsen CM, Faulenbach M, Vaag A, Volund A, Ehses JA, Seifert B et al. Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med 2007; 356: 1517-1526.
-
(2007)
N Engl J Med
, vol.356
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Volund, A.4
Ehses, J.A.5
Seifert, B.6
-
9
-
-
2542541353
-
Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets
-
Maedler K, Sergeev P, Ehses JA, Mathe Z, Bosco D, Berney T et al. Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets. Proc Natl Acad Sci USA 2004; 101: 8138-8143.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8138-8143
-
-
Maedler, K.1
Sergeev, P.2
Ehses, J.A.3
Mathe, Z.4
Bosco, D.5
Berney, T.6
-
10
-
-
0029817047
-
The role of interleukin-1 in the pathogenesis of IDDM
-
Mandrup-Poulsen T. The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia 1996; 39: 1005-1029.
-
(1996)
Diabetologia
, vol.39
, pp. 1005-1029
-
-
Mandrup-Poulsen, T.1
-
11
-
-
0022445268
-
Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans
-
Bendtzen K, Mandrup-Poulsen T, Nerup J, Nielsen JH, Dinarello CA, Svenson M. Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans. Science 1986; 232: 1545-1547.
-
(1986)
Science
, vol.232
, pp. 1545-1547
-
-
Bendtzen, K.1
Mandrup-Poulsen, T.2
Nerup, J.3
Nielsen, J.H.4
Dinarello, C.A.5
Svenson, M.6
-
12
-
-
33745315308
-
Combined interleukin-6 and interleukin-1 deficiency causes obesity in young mice
-
Chida D, Osaka T, Hashimoto O, Iwakura Y. Combined interleukin-6 and interleukin-1 deficiency causes obesity in young mice. Diabetes 2006; 55: 971-977.
-
(2006)
Diabetes
, vol.55
, pp. 971-977
-
-
Chida, D.1
Osaka, T.2
Hashimoto, O.3
Iwakura, Y.4
-
13
-
-
33745302882
-
Mature-onset obesity in interleukin-1 receptor I knockout mice
-
Garcia MC, Wernstedt I, Berndtsson A, Enge M, Bell M, Hultgren O et al. Mature-onset obesity in interleukin-1 receptor I knockout mice. Diabetes 2006; 55: 1205-1213.
-
(2006)
Diabetes
, vol.55
, pp. 1205-1213
-
-
Garcia, M.C.1
Wernstedt, I.2
Berndtsson, A.3
Enge, M.4
Bell, M.5
Hultgren, O.6
-
14
-
-
33144466102
-
Decreased fat mass in interleukin-1 receptor antagonistdeficient mice: Impact on adipogenesis, food intake, and energy expenditure
-
Somm E, Henrichot E, Pernin A, Juge-Aubry CE, Muzzin P, Dayer JM et al. Decreased fat mass in interleukin-1 receptor antagonistdeficient mice: impact on adipogenesis, food intake, and energy expenditure. Diabetes 2005; 54: 3503-3509.
-
(2005)
Diabetes
, vol.54
, pp. 3503-3509
-
-
Somm, E.1
Henrichot, E.2
Pernin, A.3
Juge-Aubry, C.E.4
Muzzin, P.5
Dayer, J.M.6
-
15
-
-
0141784866
-
IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions
-
Matsuki T, Horai R, Sudo K, Iwakura Y. IL-1 plays an important role in lipid metabolism by regulating insulin levels under physiological conditions. J Exp Med 2003; 198: 877-888.
-
(2003)
J Exp Med
, vol.198
, pp. 877-888
-
-
Matsuki, T.1
Horai, R.2
Sudo, K.3
Iwakura, Y.4
-
16
-
-
33745805908
-
Interleukin-1 system gene polymorphisms are associated with fat mass in young men
-
Strandberg L, Lorentzon M, Hellqvist A, Nilsson S, Wallenius V, Ohlsson C et al. Interleukin-1 system gene polymorphisms are associated with fat mass in young men. J Clin Endocrinol Metab 2006; 91: 2749-2754.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 2749-2754
-
-
Strandberg, L.1
Lorentzon, M.2
Hellqvist, A.3
Nilsson, S.4
Wallenius, V.5
Ohlsson, C.6
-
17
-
-
40149105682
-
IL6 and IL1B polymorphisms are associated with fat mass in older men: The MrOS Study Sweden
-
Strandberg L, Mellström D, Ljunggren Ö, Grundberg E, Karlsson MK, Holmberg AH et al. IL6 and IL1B polymorphisms are associated with fat mass in older men: the MrOS Study Sweden. Obesity (Silver Spring) 2008; 16: 710-713.
-
(2008)
Obesity (Silver Spring)
, vol.16
, pp. 710-713
-
-
Strandberg, L.1
Mellström, D.2
Ljunggren, O.3
Grundberg, E.4
Karlsson, M.K.5
Holmberg, A.H.6
-
18
-
-
20844437783
-
Age of attainment of peak bone mass is site specific in Swedish men - The GOOD study
-
Lorentzon M, Mellström D, Ohlsson C. Age of attainment of peak bone mass is site specific in Swedish men - The GOOD study. J Bone Miner Res 2005; 20: 1223-1227.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 1223-1227
-
-
Lorentzon, M.1
Mellström, D.2
Ohlsson, C.3
-
19
-
-
33645333405
-
Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden
-
Mellström D, Johnell O, Ljunggren Ö, Eriksson AL, Lorentzon M, Mallmin H et al. Free testosterone is an independent predictor of BMD and prevalent fractures in elderly men: MrOS Sweden. J Bone Miner Res 2006; 21: 529-535.
-
(2006)
J Bone Miner Res
, vol.21
, pp. 529-535
-
-
Mellström, D.1
Johnell, O.2
Ljunggren, O.3
Eriksson, A.L.4
Lorentzon, M.5
Mallmin, H.6
-
20
-
-
2442667212
-
Highly parallel SNP genotyping
-
Fan JB, Oliphant A, Shen R, Kermani BG, Garcia F, Gunderson KL et al. Highly parallel SNP genotyping. Cold Spring Harb Symp Quant Biol 2003; 68: 69-78.
-
(2003)
Cold Spring Harb Symp Quant Biol
, vol.68
, pp. 69-78
-
-
Fan, J.B.1
Oliphant, A.2
Shen, R.3
Kermani, B.G.4
Garcia, F.5
Gunderson, K.L.6
-
21
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265.
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
22
-
-
43549093332
-
Cytokines and beta-cell biology: From concept to clinical translation
-
Donath MY, Storling J, Berchtold LA, Billestrup N, MandrupPoulsen T. Cytokines and beta-cell biology: from concept to clinical translation. Endocr Rev 2008; 29: 334-350.
-
(2008)
Endocr Rev
, vol.29
, pp. 334-350
-
-
Donath, M.Y.1
Storling, J.2
Berchtold, L.A.3
Billestrup, N.4
MandrupPoulsen, T.5
-
23
-
-
0036152683
-
Interleukin-6-deficient mice develop matureonset obesity
-
Wallenius V, Wallenius K, Ahren B, Rudling M, Carlsten H, Dickson SL et al. Interleukin-6-deficient mice develop matureonset obesity. Nat Med 2002; 8: 75-79.
-
(2002)
Nat Med
, vol.8
, pp. 75-79
-
-
Wallenius, V.1
Wallenius, K.2
Ahren, B.3
Rudling, M.4
Carlsten, H.5
Dickson, S.L.6
-
24
-
-
33947305970
-
Central interleukin-1 (IL1) signaling is required for pharmacological, but not physiological, effects of leptin on energy balance
-
Wisse BE, Ogimoto K, Morton GJ, Williams DL, Schwartz MW. Central interleukin-1 (IL1) signaling is required for pharmacological, but not physiological, effects of leptin on energy balance. Brain Res 2007; 1144: 101-106.
-
(2007)
Brain Res
, vol.1144
, pp. 101-106
-
-
Wisse, B.E.1
Ogimoto, K.2
Morton, G.J.3
Williams, D.L.4
Schwartz, M.W.5
-
25
-
-
0033536008
-
Leptin actions on food intake and body temperature are mediated by IL-1
-
Luheshi GN, Gardner JD, Rushforth DA, Loudon AS, Rothwell NJ. Leptin actions on food intake and body temperature are mediated by IL-1. Proc Natl Acad Sci U S A 1999; 96: 7047-7052.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 7047-7052
-
-
Luheshi, G.N.1
Gardner, J.D.2
Rushforth, D.A.3
Loudon, A.S.4
Rothwell, N.J.5
-
26
-
-
0036963505
-
IL-1 receptor antagonist serum levels are increased in human obesity: A possible link to the resistance to leptin?
-
Meier CA, Bobbioni E, Gabay C, Assimacopoulos-Jeannet F, Golay A, Dayer JM. IL-1 receptor antagonist serum levels are increased in human obesity: a possible link to the resistance to leptin? J Clin Endocrinol Metab 2002; 87: 1184-1188.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 1184-1188
-
-
Meier, C.A.1
Bobbioni, E.2
Gabay, C.3
Assimacopoulos-Jeannet, F.4
Golay, A.5
Dayer, J.M.6
-
27
-
-
31544456615
-
Role of hypothalamic interleukin-1beta (IL-1beta) in regulation of energy homeostasis by melanocortins
-
Wisse BE, Ogimoto K, Schwartz MW. Role of hypothalamic interleukin-1beta (IL-1beta) in regulation of energy homeostasis by melanocortins. Peptides 2006; 27: 265-273.
-
(2006)
Peptides
, vol.27
, pp. 265-273
-
-
Wisse, B.E.1
Ogimoto, K.2
Schwartz, M.W.3
-
28
-
-
34548089185
-
Regulation of central melanocortin signaling by interleukin1 beta
-
Scarlett JM, Jobst EE, Enriori PJ, Bowe DD, Batra AK, Grant WF et al. Regulation of central melanocortin signaling by interleukin1 beta. Endocrinology 2007; 148: 4217-4225.
-
(2007)
Endocrinology
, vol.148
, pp. 4217-4225
-
-
Scarlett, J.M.1
Jobst, E.E.2
Enriori, P.J.3
Bowe, D.D.4
Batra, A.K.5
Grant, W.F.6
-
29
-
-
0034985788
-
Anorexic but not pyrogenic actions of interleukin-1 are modulated by central melanocortin-3/4 receptors in the rat
-
Lawrence CB, Rothwell NJ. Anorexic but not pyrogenic actions of interleukin-1 are modulated by central melanocortin-3/4 receptors in the rat. J Neuroendocrinol 2001; 13: 490-495.
-
(2001)
J Neuroendocrinol
, vol.13
, pp. 490-495
-
-
Lawrence, C.B.1
Rothwell, N.J.2
-
30
-
-
0035100026
-
Dorsal and ventral medullary catecholamine cell groups contribute differentially to systemic interleukin-1beta-induced hypothalamic pituitary adrenal axis responses
-
Buller K, Xu Y, Dayas C, Day T. Dorsal and ventral medullary catecholamine cell groups contribute differentially to systemic interleukin-1beta-induced hypothalamic pituitary adrenal axis responses. Neuroendocrinology 2001; 73: 129-138.
-
(2001)
Neuroendocrinology
, vol.73
, pp. 129-138
-
-
Buller, K.1
Xu, Y.2
Dayas, C.3
Day, T.4
-
31
-
-
0842346194
-
Polymorphism of interleukin-1 receptor antagonist gene and obesity
-
Um JY, Lee KM, Kim HM. Polymorphism of interleukin-1 receptor antagonist gene and obesity. Clin Chim Acta 2004; 340: 173-177.
-
(2004)
Clin Chim Acta
, vol.340
, pp. 173-177
-
-
Um, J.Y.1
Lee, K.M.2
Kim, H.M.3
-
32
-
-
0035083730
-
Association of the interleukin 1 receptor antagonist gene with ulcerative colitis in Northern European Caucasians
-
Carter MJ, di Giovine FS, Jones S, Mee J, Camp NJ, Lobo AJ et al. Association of the interleukin 1 receptor antagonist gene with ulcerative colitis in Northern European Caucasians. Gut 2001; 48: 461-467.
-
(2001)
Gut
, vol.48
, pp. 461-467
-
-
Carter, M.J.1
di Giovine, F.S.2
Jones, S.3
Mee, J.4
Camp, N.J.5
Lobo, A.J.6
-
33
-
-
22744445252
-
Free testosterone is a positive, whereas free estradiol is a negative, predictor of cortical bone size in young Swedish men: The GOOD study
-
Lorentzon M, Swanson C, Andersson N, Mellström D, Ohlsson C. Free testosterone is a positive, whereas free estradiol is a negative, predictor of cortical bone size in young Swedish men: the GOOD study. J Bone Miner Res 2005; 20: 1334-1341.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 1334-1341
-
-
Lorentzon, M.1
Swanson, C.2
Andersson, N.3
Mellström, D.4
Ohlsson, C.5
-
34
-
-
33750999329
-
IL-1 receptor antagonist in metabolic diseases: Dr Jekyll or Mr Hyde?
-
Perrier S, Darakhshan F, Hajduch E. IL-1 receptor antagonist in metabolic diseases: Dr Jekyll or Mr Hyde? FEBS Lett 2006; 580: 6289-6294.
-
(2006)
FEBS Lett
, vol.580
, pp. 6289-6294
-
-
Perrier, S.1
Darakhshan, F.2
Hajduch, E.3
|