Modification of dietary copper levels on the early stage of tumor-promotion with propylthiouracil in a rat two-stage thyroid carcinogenesis model

Chemico-Biological Interactions

Volumn 180, Issue 2, 2009, Pages 262-270

  Shima, Tomomi ^a   Nishimura, Jihei ^a,b   Dewa, Yasuaki ^a,b   Saegusa, Yukie ^a,b   Matsumoto, Sayaka ^a,b   Kawai, Masaomi ^a,b   Harada, Tomoaki ^a   Mitsumori, Kunitoshi ^a   Shibutani, Makoto ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

Cell proliferation; Ceruloplasmin (Cp); Copper (Cu); Metallothionein (MT); Thyroid carcinogenesis

Indexed keywords

CELL CYCLE PROTEIN; CELL CYCLE PROTEIN 2A; CERULOPLASMIN; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; CYCLIN B1; GLUTATHIONE PEROXIDASE 1; GLUTATHIONE PEROXIDASE 2; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; KI 67 ANTIGEN; MANGANESE SUPEROXIDE DISMUTASE; METALLOTHIONEIN I; METALLOTHIONEIN II; PEROXIREDOXIN 2; PROPYLTHIOURACIL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER MODEL; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DIETARY INTAKE; DOWN REGULATION; HISTOPATHOLOGY; IMMUNOLOCALIZATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; THYROID ADENOMA; THYROID CANCER; THYROID FOLLICLE CELL; THYROID HYPERPLASIA; THYROTROPIN BLOOD LEVEL; UPREGULATION;

ANIMALS; CERULOPLASMIN; COPPER; DIET; DOSE-RESPONSE RELATIONSHIP, DRUG; IRON; LIVER; MALE; METALLOTHIONEIN; ORGAN SIZE; OXIDATIVE STRESS; PROPYLTHIOURACIL; RATS; THYROID GLAND; THYROID NEOPLASMS; THYROTROPIN; THYROXINE; TRIIODOTHYRONINE;

ANIMALIA; RATTUS;

EID: 67349247515     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2009.02.002     Document Type: Article

References (44)

1. Schneider A.B., and Sarne D.H. Long-term risks for thyroid cancer and other neoplasms after exposure to radiation. Nat. Clin. Pract. Endocrinol. Metab. 1 (2005) 82-91
2. Kitahori Y., Hiasa Y., Konishi N., Enoki N., Shimoyama T., and Miyashiro A. Effect of propylthiouracil on the thyroid tumorigenesis induced by N-bis(2-hydroxypropyl)nitrosamine in rats. Carcinogenesis 5 (1984) 657-660
3. Jemec B. Studies of the goitrogenic and tumorigenic effect of two goitrogens in combination with hypophysectomy or thyroid hormone treatment. Cancer 45 (1980) 2138-2148
4. Smith P., Williams E.D., and Wynford-Thomas D. In vitro demonstration of a TSH-specific growth desensitising mechanism in rat thyroid epithelium. Mol. Cell. Endocrinol. 51 (1987) 51-58
5. Brewer C., Yeager N., and Di Cristofano A. Thyroid-stimulating hormone initiated proliferative signals converge in vivo on the mTOR kinase without activating AKT. Cancer Res. 67 (2007) 8002-8006
6. G.H. Woo, M. Takahashi, K. Inoue, H. Fujimoto, K. Igarashi, J. Kanno, M. Hirose, A. Nishikawa, M. Shibutani, Cellular distributions of molecules with altered expression specific to thyroid proliferative lesions developing in a rat thyroid carcinogenesis model, Cancer Sci. (2009) doi:10.1111/j.1349-7006.2009.01094.x.
7. Gaetano C. Reduced serum ceruloplasmin levels in hereditary haemochromatosis. Br. J. Haematol. 114 (2001) 226-229
8. Vasák M. Advances in metallothionein structure and functions. J. Trace Elem. Med. Biol. 19 (2005) 13-17
9. Nartey N., Cherian M.G., and Banerjee D. Immunohistochemical localization of metallothionein in human thyroid tumors. Am. J. Pathol. 129 (1987) 177-182
10. Cherian M.G., Jayasurya A., and Bay B.H. Metallothioneins in human tumors and potential roles in carcinogenesis. Mutat. Res. 533 (2003) 201-209
11. Tønnesen T., Kleijer W.J., and Horn N. Incidence of Menkes disease. Hum. Genet. 86 (1991) 408-410
12. Tønnesen T., Petterson A., Kruse T.A., Gerdes A.M., and Horn N. Multipoint linkage analysis in Menkes disease. Am. J. Hum. Genet. 50 (1992) 1012-1017
13. Suzuki K.T., Someya A., Komada Y., and Ogra Y. Roles of metallothionein in copper homeostasis: responses to Cu-deficient diets in mice. J. Inorg. Biochem. 88 (2002) 173-182
14. Cockell K.A., Wotherspoon A.T., Belonje B., Fritz M.E., Madère R., Hidiroglou N., Plouffe L.J., Ratnayake W.M., and Kubow S. Limited effects of combined dietary copper deficiency/iron overload on oxidative stress parameters in rat liver and plasma. J. Nutr. Biochem. 16 (2005) 750-756
15. Alissa E.M., Bahijri S.M., Lamb D.J., and Ferns G.A. The effects of coadministration of dietary copper and zinc supplements on atherosclerosis, antioxidant enzymes and indices of lipid peroxidation in the cholesterol-fed rabbit. Int. J. Exp. Pathol. 85 (2004) 265-275
16. Galhardi C.M., Diniz Y.S., Rodrigues H.G., Faine L.A., Burneiko R.C., Ribas B.O., and Novelli E.L. Beneficial effects of dietary copper supplementation on serum lipids and antioxidant defenses in rats. Ann. Nutr. Metab. 49 (2005) 283-288
17. Lamb D.J., Reeves G.L., Taylor A., and Ferns G.A. Dietary copper supplementation reduces atherosclerosis in the cholesterol-fed rabbit. Atherosclerosis 146 (1999) 33-43
18. Maritz G.S., and Windvogel S. Is maternal copper supplementation during alveolarization protecting the developing rat lung against the adverse effects of maternal nicotine exposure? A morphometric study. Exp. Lung Res. 29 (2003) 243-260
19. Mark-Savage P., Keen C.L., and Hurley L.S. Reduction by copper supplementation of teratogenic effects of d-penicillamine. J. Nutr. 113 (1983) 501-510
20. Milanino R., Marrella M., Crivellente F., Benoni G., and Cuzzolin L. Nutritional supplementation with copper in the rat. I. Effects on adjuvant arthritis development and on some in vivo- and ex vivo-markers of blood neutrophils. Inflamm. Res. 49 (2000) 214-223
21. Webster R.P., Gawde M.D., and Bhattacharya R.K. Modulation by dietary copper of aflatoxin B1-induced activity of DNA repair enzymes poly (ADP-ribose) polymerase, DNA polymerase beta and DNA ligase. In Vivo 10 (1996) 533-536
22. Klaunig J.E., Xu Y., Isenberg J.S., Bachowski S., Kolaja K.L., Jiang J., Stevenson D.E., and Walborg Jr. E.F. The role of oxidative stress in chemical carcinogenesis. Environ. Health Perspect. 106 Suppl. 1 (1998) 289-295
23. Gitilin J.D. Mechanism of caeruloplasmin biosynthesis in normal and copper-deficient rats. J. Biochem. 282 (1992) 835-839
24. Cohen N.L., Keen C.L., Lönnerdal B., and Hurley L.S. The effect of copper supplementation on the teratogenic effects of triethylenetetramine in rats. Drug Nutr. Interact. 2 (1983) 203-210
25. Imai T., Onose J., Hasumura M., Ueda M., Takizawa T., and Hirose M. Sequential analysis of development of invasive thyroid follicular cell carcinomas in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation. Toxicol. Pathol. 32 (2004) 229-236
26. T method. Methods 25 (2001) 402-408
27. Draetta G., Luca F., Westendorf J., Brizuela L., Ruderman J., and Beach D. cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF. Cell 56 (1989) 829-838
28. Chen H., Huang Q., Dong J., Zhai D.Z., Wang A.D., and Lan Q. Overexpression of CDC2/CyclinB1 in gliomas, and CDC2 depletion inhibits proliferation of human glioma cells in vitro and in vivo. BMC Cancer 8 (2008) 29
29. Kaushal N., and Bansal M.P. Dietary selenium validation-induced oxidative stress modulates CDC2/cycinB1 expression and apoptosis of germ cells in mice testis. J. Nutr. Biochem. 18 (2007) 553-564
30. Viarengo A., Burlando B., Ceratto N., and Panfoli I. Antioxidant role of metallothioneins: a comparative overview. Cell. Mol. Biol. (Noisy-le-grand) 46 (2000) 407-417
31. Lelkes P.I., Hahn K.L., Sukovich D.A., Karmiol S., and Schmidt D.H. On the possible role of reactive oxygen species in angiogenesis. Adv. Exp. Med. Biol. 454 (1998) 295-310
32. Suh Y.A., Arnold R.S., Lassegue B., Shi J., Xu X., Sorescu D., Chung A.B., Griendling K.K., and Lambeth J.D. Cell transformation by the superoxidase-generating oxidase Mox1. Nature 401 (1999) 79-82
33. Chakraborty T. Cell proliferation and hepatocarcinogenesis in rat initiated by diethylnitrosamine and promoted by phenobarbital: potential roles of early DNA damage and liver metallothionein expression. Life Sci. 81 (2007) 489-499
34. Jin R., Chow V.T., Tan P.H., Dheen S.T., Duan W., and Bay B.H. Metallothionein 2A expression is associated with cell proliferation in breast cancer. Carcinogenesis 23 (2002) 81-86
35. Umemura T., Kai S., Hasegawa R., Kanki K., Kitamura Y., Nishikawa A., and Hirose M. Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion. Carcinogenesis 24 (2003) 1105-1109
36. Bertinato J., Iskandar M., and L'Abbé M.R. Copper deficiency induces the upregulation of the copper chaperone for Cu/Zn superoxide dismutase in weanling male rats. J. Nutr. 133 (2003) 28-31
37. Bednarek J., Wysocki H., and Sowinski J. Oxidation products and antioxidant markers in plasma of patients with Graves' disease and toxic multinodular goiter: effect of methimazole treatment. Free Radic. Res. 38 (2004) 659-664
38. Das K., and Chainy G.B. Thyroid hormone influences antioxidant defense system in adult rat brain. Neurochem. Res. 29 (2004) 1755-1766
39. Maier J., van Steeg H., van Oostrom C., Paschke R., Weiss R.E., and Krohn K. Iodine deficiency activates antioxidant genes and causes DNA damage in the thyroid gland of rats and mice. Biochim. Biophys. Acta 1773 (2007) 990-999
40. Abe M., Suzuki N., Yoshida M., Usuda K., Furukawa S., Juneja L.R., Okubo T., and Nakae D. Possible carcinogenic risks of copper gluconate and their prevention by co-administered green tea catechins evaluated by a rat medium-term multi-organ carcinogenicity bioassay protocol. Food Chem. Toxicol. 46 (2008) 1760-1770
41. Olin K.L., Walter R.M., and Keen C.L. Copper deficiency affects selenoglutathione peroxidase and selenodeiodinase activities and antioxidant defense in weanling rats. Am. J. Clin. Nutr. 59 (1994) 654-658
42. Abe M., Suzuki N., Yoshida M., Igarashi M., Usuda K., Furukawa S., Maekawa A., Juneja L.R., Okubo T., and Nakae D. Preliminary evaluation of toxicologic and carcinogenic risks of copper gluconate in rats given multiple carcinogens. J. Toxicol. Pathol. 19 (2006) 129-135
43. Saari J.T. Renal copper as an index of copper status in marginal deficiency. Biol. Trace Elem. Res. 86 (2002) 237-247
44. Kralik A., Kirchgessner M., and Eder K. Concentrations of thyroid hormones in serum and activity of hepatic 5′ monodeiodinase in copper-deficient rats. Z. Ernahrungswiss. 35 (1996) 288-291