Possible carcinogenic risks of copper gluconate and their prevention by co-administered green tea catechins evaluated by a rat medium-term multi-organ carcinogenicity bioassay protocol

Food and Chemical Toxicology

Volumn 46, Issue 5, 2008, Pages 1760-1770

  Abe, Masayoshi ^a   Suzuki, Noriko ^b   Yoshida, Midori ^c   Usuda, Koji ^a   Furukawa, Satoshi ^a   Juneja, Lekh Raj ^d   Okubo, Tsutomu ^d   Nakae, Dai ^e,f  

^a NISSAN CHEMICAL INDUSTRIES LTD   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c Research Center for Radiation Protection   (Japan)

^d TAIYO KAGAKU CO LTD   (Japan)

^e TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

^f TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

Author keywords

8 oxoguanine; Copper gluconate; Green tea catechins; Oxidative stress; Rat medium term multi organ carcinogenicity bioassay protocol

Indexed keywords

1,2 DIMETHYLHYDRAZINE; BIS(2 HYDROXYPROPYL)NITROSAMINE; CATECHIN; DIETHYLNITROSAMINE; GLUCONATE COPPER; GLUTATHIONE TRANSFERASE; GREEN TEA EXTRACT; METHYLNITROSOUREA; N BUTYL N (4 HYDROXYBUTYL)NITROSAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; CANCER RISK; CARCINOGENICITY; CONTROLLED STUDY; EVALUATION; EXPOSURE; FORESTOMACH; HYPERPLASIA; INCIDENCE; LIVER CANCER; LIVER INJURY; MALE; NONHUMAN; PLACENTA; RAT; STOMACH CANCER;

ANIMALS; ANTICARCINOGENIC AGENTS; BODY WEIGHT; CARCINOGENICITY TESTS; CARCINOGENS; CATECHIN; COPPER; DRINKING; GLUCONATES; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; LIVER; MALE; ORGAN SIZE; RATS; RATS, WISTAR; TEA;

RATTUS;

EID: 40849126490     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.01.024     Document Type: Article

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