Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1794, Issue 6, 2009, Pages 873-881

  Lima, Luis Maurício T R ^a   Becker, Camila Franco ^b   Giesel, Guilherme Menegon ^b   Marques, Adriana Fonseca ^a   Cargnelutti, Maria Thereza ^a   de Oliveira Neto, Mario ^c   Queiroz Monteiro, Robson ^a   Verli, Hugo ^b   Polikarpov, Igor ^c  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Crystallography; Molecular dynamic simulation; Small angle X ray scattering; Suramin; Thrombin

Indexed keywords

FIBRINOGEN; NANOPARTICLE; SURAMIN; THROMBIN;

ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; COMPLEX FORMATION; CRYSTAL STRUCTURE; HUMAN; LIGAND BINDING; MOLECULAR DYNAMICS; OPTICAL RESOLUTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; SCATTERING, RADIATION; SOLUTIONS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SURAMIN; THERMODYNAMICS; THROMBIN;

EID: 67349239065     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2009.03.011     Document Type: Article

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