Suramin and Suramin Analogues Inhibit Merozoite Surface Protein-1 Secondary Processing and Erythrocyte Invasion by the Malaria Parasite Plasmodium falciparum

Journal of Biological Chemistry

Volumn 278, Issue 48, 2003, Pages 47670-47677

  Fleck, Suzanne L ^a   Birdsall, Berry ^b   Babon, Jeffrey ^b   Dluzewski, Anton R ^c   Martin, Stephen R ^b   Morgan, William D ^b   Angov, Evelina ^d   Kettleborough, Catherine A ^a   Feeney, James ^b   Blackman, Michael J ^b   Holder, Anthony A ^b  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c GUY S HOSPITAL   (United Kingdom)

^d WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CALORIMETRY; ENZYMES; FLUORESCENCE; ISOTHERMS; NUCLEAR MAGNETIC RESONANCE; TITRATION; VIRUSES;

PROTEOLYSIS;

BIOCHEMISTRY;

MEROZOITE SURFACE PROTEIN 1; PROTEINASE; SURAMIN; SURAMIN DERIVATIVE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; DRUG PROTEIN BINDING; DRUG STRUCTURE; ERYTHROCYTE; HOST PARASITE INTERACTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING;

2-NAPHTHYLAMINE; ANIMALS; ANTIPROTOZOAL AGENTS; BLOTTING, WESTERN; CALORIMETRY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASES; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MEROZOITE SURFACE PROTEIN 1; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PROTEIN BINDING; SPECTROMETRY, FLUORESCENCE; SURAMIN; TEMPERATURE; UREA;

PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PROTOZOA;

EID: 10744227483     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M306603200     Document Type: Article

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