Accurate potentiometric determination of lipid membrane-water partition coefficients and apparent dissociation constants of ionizable drugs: Electrostatic corrections

Pharmaceutical Research

Volumn 26, Issue 6, 2009, Pages 1332-1343

  Elsayed, Mustafa M A ^a   Vierl, Ulrich ^a   Cevc, Gregor ^a  

^a IDEA AG   (Germany)

Author keywords

Bupivacaine; Diclofenac; Drug binding; Ketoprofen; Potentiometric titration; Terbinafine

Indexed keywords

BUPIVACAINE; DICLOFENAC; KETOPROFEN; TERBINAFINE; WATER;

ACCURACY; ANALYTIC METHOD; ARTICLE; DATA ANALYSIS; DISSOCIATION CONSTANT; DRUG BINDING; ELECTRICITY; IONIZATION; LIPID MEMBRANE; LIPOPHILICITY; PARTITION COEFFICIENT; POTENTIOMETRIC TITRATION; PRIORITY JOURNAL; RELIABILITY;

BUPIVACAINE; DICLOFENAC; IONS; KETOPROFEN; MEMBRANE LIPIDS; NAPHTHALENES; OSMOLAR CONCENTRATION; PHARMACEUTICAL PREPARATIONS; POTENTIOMETRY; SENSITIVITY AND SPECIFICITY; SOLUBILITY; STATIC ELECTRICITY; TITRIMETRY; WATER;

EID: 67349193196     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9842-1     Document Type: Article

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