TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants

Journal of Allergy and Clinical Immunology

Volumn 123, Issue 5, 2009, Pages

  Suttner, Kathrin ^a   Rosenstiel, Philip ^b   Depner, Martin ^c   Schedel, Michaela ^a   Pinto, Leonardo A ^c   Ruether, Andreas ^b   Adamski, Jerzy ^d   Klopp, Norman ^d   Illig, Thomas ^d   Vogelberg, Christian ^e   Schreiber, Stefan ^b   von Mutius, Erika ^c   Kabesch, Michael ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^c LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

association study; asthma; functional promoter analysis; genetic analysis; HLX1; risk score model; TBX21

Indexed keywords

T BOX TRANSCRIPTION FACTOR;

ARTICLE; ASTHMA; ATOPY; CHILDHOOD DISEASE; GENE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HLX1 GENE; HUMAN; MAJOR CLINICAL STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; TBX21 GENE; TH1 CELL; TH2 CELL;

ALLELES; ASTHMA; CASE-CONTROL STUDIES; CHILD; CROSS-SECTIONAL STUDIES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GERMANY; HOMEODOMAIN PROTEINS; HUMANS; LINKAGE DISEQUILIBRIUM; POLYMORPHISM, SINGLE NUCLEOTIDE; PREVALENCE; PROMOTER REGIONS, GENETIC; T-BOX DOMAIN PROTEINS; TRANSCRIPTION FACTORS;

EID: 67349166686     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.02.025     Document Type: Article

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