Persistent versus transient depressive symptoms in relation to platelet hyperactivation: A longitudinal analysis of dementia caregivers

Journal of Affective Disorders

Volumn 116, Issue 1-2, 2009, Pages 80-87

  Aschbacher, Kirstin ^a   Roepke, Susan K ^a   von Känel, Roland ^a,b   Mills, Paul J ^a   Mausbach, Brent T ^a   Patterson, Thomas L ^a,c   Dimsdale, Joel E ^a   Ziegler, Michael G ^d   Ancoli Israel, Sonia ^a,c   Grant, Igor ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF BERN   (Switzerland)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cardiovascular disease; Cell adhesion molecule; Coagulation; P selectin; Spousal dementia caregiving

Indexed keywords

CELL ADHESION MOLECULE; PADGEM PROTEIN;

ADULT; AFFECT; AGED; ALZHEIMER DISEASE; ARTICLE; BLOOD CLOTTING; BRIEF SYMPTOM INVENTORY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAREGIVER; CAREGIVER BURDEN; CELL ADHESION; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMENTIA; DEPRESSION; FEMALE; FLOW CYTOMETRY; HEMOSTASIS; HOME CARE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MENTAL STRESS; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION;

AGED; AGED, 80 AND OVER; BLOOD PLATELETS; CAREGIVERS; DEMENTIA; DEPRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; MODELS, STRUCTURAL; P-SELECTIN; PERSONALITY INVENTORY; PLATELET ACTIVATION; PSYCHIATRIC STATUS RATING SCALES; RISK FACTORS; STRESS, PSYCHOLOGICAL; TIME FACTORS;

EID: 67349160566     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jad.2008.11.008     Document Type: Article

References (56)

1. Akaike H. A new look at the statistical model identification. IEEE Transactions on Automatic Control 19 (1974) 716-723
2. Anda R., Williamson D., Jones D., Macera C., Eaker E., Glassman A., and Marks J. Depressed affect, hopelessness, and the risk of ischemic heart disease in a cohort of U.S. adults. Epidemiology 4 (1993) 285-294
3. Ariyo A.A., Haan M., Tangen C.M., Rutledge J.C., Cushman M., Dobs A., and Furberg C.D. Depressive symptoms and risks of coronary heart disease and mortality in elderly Americans. Cardiovascular Health Study Collaborative Research Group. Circulation 102 (2000) 1773-1779
4. Aschbacher K., Von Känel R., Dimsdale J.E., Patterson T.L., Mills P.J., Mausbach B.T., Ancoli-Israel S., and Grant I. Increasing dementia of the care receiver predicts procoagulant response in Alzheimer caregivers. American Journal of Geriatric Psychiatry 14 (2006) 694-703
5. Aschbacher K., Von Känel R., Mills P.J., Hong S., Patterson T.L., Roepke S.K., Mausbach B.T., Ziegler M.G., Dimsdale J.E., Ancoli-Israel S., and Grant I. Effects of depressive and anxious symptoms on norepinephrine and platelet P-selectin responses to acute psychological stress among elderly caregivers. Brain, Behavior & Immunity 22 (2008) 493-502
6. Aschbacher K., Von Känel R., Mills P.J., Roepke S.K., Hong S., Dimsdale J.E., Mausbach B.T., Patterson T.L., Ziegler M.G., Ancoli-Israel S., and Grant I. Longitudinal platelet reactivity to acute psychological stress among older men and women. Stress (2008)
7. Barefoot J.C., and Schroll M. Symptoms of depression, acute myocardial infarction, and total mortality in a community sample. Circulation 93 (1996) 1976-1980
8. Bentler P.M., and Yuan K.H. Structural equation modeling with small samples: test statistics. Multivariate Behavioral Research 34 (1999) 181-197
9. Bianchi M., Moser C., Lazzarini C., Vecchiato E., and Crespi F. Forced swimming test and fluoxetine treatment: in vivo evidence that peripheral 5-HT in rat platelet-rich plasma mirrors cerebral extracellular 5-HT levels, whilst 5-HT in isolated platelets mirrors neuronal 5-HT changes. Experimental Brain Research 143 (2002) 191-197
10. Blann A.D., Nadar S.K., and Lip G.Y. The adhesion molecule P-selectin and cardiovascular disease. European Heart Journal 24 (2003) 2166-2179
11. Bondy B. Common genetic factors for depression and cardiovascular disease. Dialogues in Clinical Neuroscience 9 (2007) 19-28
12. Caspi A., Sugden K., Moffitt T.E., Taylor A., Craig I.W., Harrington H., Mcclay J., Mill J., Martin J., Braithwaite A., and Poulton R. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301 (2003) 386-389
13. Chen M., and Geng J. P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis and cancer growth and metastasis. Archivum Immunologiae et Therapiae Experimentalis (2006) 54
14. De Clerck F., Xhonneux B., and De Chaffoy De Courcelles D. Functional expression of the amplification reaction between serotonin and epinephrine on platelets. Journal of Cardiovascular Pharmacology 11 (1988) S1-S5
15. Derogatis L.R. The Brief Symptom Inventory: Administration, Scoring and Procedures Manual-II (1992), Clinical Psychometric Research, Inc., New York
16. Derogatis L.R., and Melisaratos N. The Brief Symptom Inventory: an introductory report. Psychological medicine 13 (1983) 595-605
17. Eley T.C., Sugden K., Corsico A., Gregory A.M., Sham P., Mcguffin P., Plomin R., and Craig I.W. Gene-environment interaction analysis of serotonin system markers with adolescent depression. Molecular Psychiatry 9 (2004) 908-915
18. Glassman A.H., Bigger J.T., Gaffney M., Shapiro P.A., and Swenson R. Onset of major depression associated with acute coronary syndromes. Archives of General Psychiatry 63 (2006) 283-288
19. Hale W.D., Cochran C.D., and Hedgepeth B.E. Norms for the elderly on the Brief Symptom Inventory. Journal of Consulting & Clinical Psychology 52 (1984) 321-322
20. Hamer M., Gibson E.L., Vuononvirta R., Williams E., and Steptoe A. Inflammatory and hemostatic responses to repeated mental stress: individual stability and habituation over time. Brain, Behavior & Immunity 20 (2006) 456-459
21. Harrison P. Progress in the assessment of platelet function. British Journal of Haematology 111 (2000) 733-744
22. Hu L., and Bentler P.M. Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Structural Equation Modeling 6 (1999) 1-55
23. Koyama H., Maeno T., Fukumoto S., Shoji T., Yamane T., Yokoyama H., Emoto M., Shoji T., Tahara H., Inaba M., Hino M., Shioi A., Miki T., and Nishizawa Y. Platelet P-selectin expression is associated with atherosclerotic wall thickness in carotid artery in humans. Circulation 108 (2003) 524-529
24. Lesch K.P. Gene-environment interaction and the genetics of depression. Review, Journal of Psychiatry & Neuroscience (2004) 3
25. Lesch K.P., Wolozin B.L., Murphy D.L., and Riederer P. Primary structure of the human platelet serotonin uptake site-identity with the brain serotonin transporter. Journal of Neurochemistry 60 (1993) 2319-2322
26. Li N., Wallen H., and Hjemdahl P. Evidence for prothrombotic effects of exercise and limited protection by aspirin. Circulation 100 (1999) 1374-1379
27. Li N., Hu H., and Hjemdahl P. Aspirin treatment does not attenuate platelet or leukocyte activation as monitored by whole blood flow cytometry. Thrombosis Research 111 (2003) 165-170
28. Libby P., Ridker P.M., and Maseri A. Inflammation and atherosclerosis. Circulation 105 (2002) 1135-1143
29. Mausbach B., Patterson T., Rabinowitz Y., Grant I., and Schulz R. Depression and distress predict time to cardiovascular disease in dementia caregivers. Health Psychology 26 (2007) 539-544
30. Mausbach B.T., Aschbacher K., Patterson T.L., Von Känel R., Dimsdale J.E., Mills P.J., Ancoli-Israel S., and Grant I. Effects of placement and bereavement on psychological well-being and cardiovascular risk in Alzheimer's caregivers: a longitudinal analysis. Journal of Psychosomatic Research 62 (2007) 439-445
31. Merten M., and Thiagarajan P. P-selectin expression on platelets determines size and stability of platelet aggregates. Circulation 102 (2000) 1931-1936
32. Michelson A., and Furman M. Laboratory markers of platelet activation and their clinical significance. Current Opinion in Hematology 6 (1999) 342-348
33. Michelson A.D., Barnard M.R., Krueger L.A., Frelinger A.L., and Furman M.I. Evaluation of platelet function by flow cytometry. Methods 21 (2000) 259-270
34. Musselman D.L., Evans D.L., and Nemeroff C.B. The relationship of depression to cardiovascular disease: epidemiology, biology, and treatment. Archives of General Psychiatry 55 (1998) 580-592
35. Musselman D.L., Marzec U.M., Manatunga A., Penna S., Reemsnyder A., Knight B.T., Baron A., Hanson S.R., and Nemeroff C.B. Platelet reactivity in depressed patients treated with paroxetine: preliminary findings. Archives of General Psychiatry 57 (2000) 875-882
36. Nemeroff C.B., and Musselman D.L. Are platelets the link between depression and ischemic heart disease?. American Heart Journal 140 (2000) S57-62
37. Otte C., Mccaffery J., Ali S., and Whooley M.A. Association of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the heart and soul study. American Journal of Psychiatry, 164 (2007) 1379-1384
38. Owens M.J., and Nemeroff C.B. Role of serotonin in the pathophysiology of depression: focus on the serotonin transporter. Clinical Chemistry 40 (1994) 288-295
39. Penninx B.W., Geerlins S.W., Deeg D.J., Van Eijk J.T., Van Tilburg W., and Beekman A.T. Minor and major depression and the risk of death in older persons. Archives of General Psychiatry 56 (1999) 889-895
40. Piletz J.E., Zhu H., Madakasira S., Pazzaglia P., Devane C.L., Goldman N., and Halaris A. Elevated P-selectin on platelets in depression: response to bupropion. Journal of Psychiatric Research 34 (2000) 397-404
41. Pollock B.G., Laghrissi-Thode F., and Wagner W.R. Evaluation of platelet activation in depressed patients with ischemic heart disease after paroxetine or nortriptyline treatment. Journal of Clinical Psychopharmacology 20 (2000) 137-140
42. Saab P.G., Llabre M.M., Hurwitz B.E., Frame C.A., Reineke L.J., Fins A.I., Mccalla J., Cieply L.K., and Schneiderman N. Myocardial and peripheral vascular responses to behavioral challenges and their stability in black and white Americans. Psychophysiology 29 (1992) 384-397
43. Schulz R., and Beach S.R. Caregiving as a risk factor for mortality: the Caregiver Health Effects Study. JAMA 282 (1999) 2215-2219
44. Schulz R., O'brien A.T., Bookwala J., and Fleissner K. Psychiatric and physical morbidity effects of dementia caregiving: prevalence, correlates and causes. Gerontologist 35 (1995) 771-791
45. Schulz R., Beach S.R., Ives D.G., Martire L.M., Ariyo A.A., and Kop W.J. Association between depression and mortality in older adults: the Cardiovascular Health Study. Archives of Internal Medicine 160 (2000) 1761-1768
46. Serebruany V.L., Suckow R.F., Cooper T.B., O'connor C.M., Malinin A.I., Krishnan K.R., Van Zyl L.T., Lekht V., and Glassman A.H. Relationship between release of platelet/endothelial biomarkers and plasma levels of sertraline and N-desmethylsertraline in acute coronary syndrome patients receiving SSRI treatment for depression. American Journal of Psychiatry 162 (2005) 1165-1170
47. Stahl S.M. Essential Pharmocology: Neuroscientific Basis and Practical Applications (2000), Cambridge University Press, Cambridge, UK
48. Stukenberg K.W., Dura J.R., and Kiecolt-Glaser J.K. Depression screening scale validation in an elderly, community-dwelling population. Psychological Assessment 2 (1990) 134-138
49. Tomfohr L.M., Martin T.M., and Miller G.E. Symptoms of depression and impaired endothilial function in healthy adolescent women. Journal of Behavioral Medicine (2007) (Electronic publication ahead of print)
50. Von Känel R. Platelet hyperactivity in clinical depression and the beneficial effect of antidepressant drug treatment: how strong is the evidence?. Acta Psychiatrica Scandinavica 110 (2004) 163-177
51. Von Känel R., Mausbach B., Patterson A., Dimsdale J., Aschbacher K., Mills M.J., Ziegler M., Ancoli-Israel S., and Grant I. Increased Framingham coronary heart disease risk score in dementia caregivers relative to non-caregiving controls. Gerontology 54 (2008) 131-137
52. Wassertheil-Smoller S., Applegate W.B., Berge K., Chang C.J., Davis B.R., Grimm R.J., Kostis J., Pressel S., and Schron E. Change in depression as a precursor of cardiovascular events. SHEP Cooperative Research Group (Systoloc Hypertension in the elderly). Archives of Internal Medicine, 156 (1996) 553-561
53. Wassertheil-Smoller S., Shumaker S., Ockene J., Talavera G.A., Greenland P., Cochrane B., Robbins J., Aragaki A., and Dunbar-Jacob J. Depression and cardiovascular sequelae in postmenopausal women. The Women's Health Initiative (WHI). Archives of internal medicine, 164 (2004) 289-298
54. Watson D., and Pennebaker J.W. Health complaints, stress and distress: exploring the central role of negative affectivity. Psychological Review 96 (1989) 234-254
55. Whyte E.M., Pollock B.G., Wagner W.R., Mulsant B.H., Ferrell R.E., Mazumdar S., and Reynolds C.F. Influence of serotonin-transporter-linked promoter region polymorphism on platelet activation in geriatric depression. American Journal of Psychiatry 158 (2001) 2074-2076
56. Williams R.B., Marchuk D.A., Gadde K.M., Carefoot J.C., Grichnik K., Helms M.J., Kuhm C., and Lewis J.G. Central nervous system serotonin function and cardiovascular responses to stress. Psychosomatic Medicine 63 (2001) 300-305