Effects of placement and bereavement on psychological well-being and cardiovascular risk in Alzheimer's caregivers: A longitudinal analysis

Journal of Psychosomatic Research

Volumn 62, Issue 4, 2007, Pages 439-445

  Mausbach, Brent T ^a   Aschbacher, Kirstin ^a   Patterson, Thomas L ^a   von Känel, Roland ^a,b   Dimsdale, Joel E ^a   Mills, Paul J ^a   Ancoli Israel, Sonia ^a,c   Grant, Igor ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b PSI   (Switzerland)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Caregiving; Hemostasis; Morbidity; Stress; Transitions

Indexed keywords

D DIMER;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BEREAVEMENT; BLOOD CLOTTING; CARDIOVASCULAR RISK; CAREGIVER; CAREGIVER BURDEN; CONTROLLED STUDY; DEPRESSION; FEMALE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; PSYCHOLOGICAL WELL BEING; REGRESSION ANALYSIS; RISK ASSESSMENT; SPOUSE;

ADAPTATION, PSYCHOLOGICAL; AGED; ALZHEIMER DISEASE; BEREAVEMENT; CARDIOVASCULAR DISEASES; CAREGIVERS; COST OF ILLNESS; DEPRESSION; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; INTERNAL-EXTERNAL CONTROL; LONG-TERM CARE; LONGITUDINAL STUDIES; MALE; PATIENT ADMISSION; PROSPECTIVE STUDIES; QUALITY OF LIFE; RISK FACTORS;

EID: 33947320970     PISSN: 00223999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpsychores.2006.10.011     Document Type: Article

References (41)

1. Administration on Aging. Older Americans 2000: key findings of well-being. www.agingstats.gov/chartbook2000/population.html [Accessed January 26, 2006]
2. Bookwala J., Yee J., and Schulz R. Caregiving and detrimental mental and physical health outcomes. In: Williamson G., and Shaffer D. (Eds). Physical illness and depression in older adults: a handbook of theory, research, and practice (2000), Plenum, Dordrecht (Netherlands) 93-131
3. Rose-Rego S., Strauss M., and Smyth K. Differences in the perceived well-being of wives and husbands caring for persons with Alzheimer's disease. Gerontologist 38 (1998) 224-230
4. Schulz R., Visintainer P., and Williamson G. Psychiatric and physical morbidity effects of caregiving. J Gerontol 45 (1990) P181-P191
5. Schulz R., and Beach S. Caregiving as a risk factor for mortality: the Caregiver Health Effects Study. JAMA 282 (1999) 2215-2219
6. Shaw W., Patterson T., Ziegler M., Dimsdale J., Semple S., and Grant I. Accelerated risk of hypertensive blood pressure recordings among Alzheimer caregivers. J Psychosom Res 46 (1999) 215-227
7. Lee S., Colditz G., Berkman L., and Kawachi I. Caregiving and risk of coronary heart disease in U.S. women: a prospective study. Am J Prev Med 24 (2003) 113-119
8. Vitaliano P., Scanlan J., Zhang J., Savage M., Hirsch I., and Siegler I. A path model of chronic stress, the metabolic syndrome, and coronary heart disease. Psychosom Med 64 (2002) 418-435
9. Mausbach BT, Patterson TL, Rabinowitz Y, Grant I, Schulz R. Depression and distress predict time to cardiovascular disease in dementia caregivers. Health Psychol [In press].
10. Pearlin L., and Schooler C. The structure of coping. J Health Soc Behav 19 (1978) 2-21
11. Penninx B., van Tilburg T., Deeg D., Kriegsman D., Boeke A., and van Eijk J. Direct and buffer effects of social support and personal coping resources in individuals with arthritis. Soc Sci Med 44 (1997) 393-402
12. Cameron J., Herridge M., Tansey C., McAndrews M., and Cheung A. Well-being in informal caregivers of survivors of acute respiratory distress syndrome. Crit Care Med 34 (2006) 81-86
13. Penninx B., van Tilburg T., Kriegsman D., Deeg D., Boeke A., and van Eijk J. Effects of social support and personal coping resources on mortality in older tage: the Longitudinal Aging Study Amsterdam. Am J Epidemiol 146 (1997) 510-519
14. Kop W. Chronic and acute psychological risk factors for clinical manifestations of coronary artery disease. Psychosom Med 61 (1999) 476-487
15. Bauer K., and Rosenberg R. The pathophysiology of the prethrombotic state in humans: insights gained from studies using markers of hemostatic system activation. Blood 70 (1987) 343-350
16. Smith E., Keen G., Grant A., and Stirk C. Fate of fibrinogen in human arterial intima. Arteriosclerosis 10 (1990) 263-275
17. Spronk H., Govers-Riemslag J., and ten Cate H. The blood coagulation system as a molecular machine. Bioessays 25 (2003) 1220-1228
18. Lip G., and Lowe G. Fibrin D-dimer: a useful clinical marker of thrombogenesis?. Clin Sci 89 (1995) 205-214
19. von Känel R., Dimsdale J., Ziegler M., Mills P., Patterson T., Lee S., et al. Effect of acute psychological stress on the hypercoagulable state in subjects (spousal caregivers of patients with Alzheimer's disease) with coronary or cerebrovascular disease and/or systemic hypertension. Am J Cardiol 87 (2001) 1405-1408
20. von Känel R., and Dimsdale J. Fibrin D-dimer: a marker of psychosocial distress and its implications for research in stress-related coronary artery disease. Clin Cardiol 26 (2003) 164-168
21. Aschbacher K., von Känel R., Dimsdale J., Patterson M., Mills P., Mausbach B., et al. Dementia severity of the care receiver predicts procoagulant response in Alzheimer caregivers. Am J Geriatr Psychiatry 14 (2006) 694-703
22. von Känel R., Dimsdale J., Patterson T., and Grant I. Association of negative life event stress with coagulation activity in elderly Alzheimer caregivers. Psychosom Med 65 (2003) 145-150
23. von Känel R., Dimsdale J., Adler K., Patterson T., Mills P., and Grant I. Effects of depressive symptoms and anxiety on hemostatic responses to acute mental stress and recovery in the elderly. Psychiatry Res 126 (2004) 253-264
24. Danesh J., Whincup P., Walker M., Lennon L., Thomson A., Appleby P., et al. Fibrin D-dimer and coronary heart disease: prospective study and meta-analysis. Circulation 103 (2001) 2323-2327
25. Burton L., Zdaniuk B., Schulz R., Jackson S., and Hirsch C. Transitions in spousal caregiving. Gerontologist 43 (2003) 230-241
26. Schulz R., Belle S., Czaja S., McGinnis K., Stevens A., and Zhang S. Long-term care placement of dementia patients and caregiver health and well-being. JAMA 292 (2004) 961-967
27. Grant I., Adler K., Patterson T., Dimsdale J., Ziegler M., and Irwin M. Health consequences of Alzheimer's caregiving transitions: effects of placement and bereavement. Psychosom Med 64 (2002) 477-486
28. Hughes C., Berg L., Danziger W., Coben L., and Martin R. A new clinical scale for the staging of dementia. Br J Psychiatry 140 (1982) 566-572
29. Pearlin L., Mullan J., Semple S., and Skaff M. Caregiving and the stress process: an overview of concepts and their measures. Gerontologist 30 (1990) 583-594
30. Seemann T. Personal control and coronary artery disease: how generalized expectancies about control may influence disease risk. J Psychosom Res 35 (1991) 661-669
31. Hamilton M. Standardised assessment and recording of depressive symptoms. Psychiatr Neurol Neurochir 72 (1969) 201-205
32. Hamilton M. General problems of psychiatric rating scales (especially depression). In: Pichot P., and Olivier-Martin R. (Eds). Psychological measurements in psychopharmacology (1974), S. Karker, Basel (Switzerland) 125-138
33. Hamilton M. Standardised assessment and recording of depressive symptoms. Psychiatr Neurol Neurochir 72 (1969) 201-205
34. Singer J., and Willett J. Applied longitudinal data analysis: modeling change and event occurrence (2003), Oxford University Press, New York
35. Barth J., Schumacher M., and Herrmann-Lingen C. Depression as a risk factor for mortality in patients with coronary heart disease: a meta-analysis. Psychosom Med 66 (2004) 802-813
36. Kiecolt-Glaser J., Preacher K., MacCallum R., Atkinson C., Malarkey W., and Glaser R. Chronic stress and age-related increases in the proinflammatory cytokine IL-6. Proc Natl Acad Sci U S A 100 (2003) 9090-9095
37. Coon D., Thompson L., Steffen A., Sorocco K., and Gallagher-Thompson D. Anger and depression management: psychoeducational skill training interventions for women caregivers of a relative with dementia. Gerontologist 43 (2003) 678-689
38. Brodaty H., Green A., and Koschera A. Meta-analysis of psychosocial interventions for caregivers of people with dementia. J Am Geriatr Soc 51 (2003) 657-664
39. Sörensen S., Pinquart M., and Duberstein P. How effective are interventions with caregivers? An updated meta-analysis. Gerontologist 42 (2002) 356-372
40. Grant I., McKibbin C., Taylor M., Mills P., Dimsdale J., Ziegler M., et al. In-home respite intervention reduces plasma epinephrine in stressed Alzheimer caregivers. Am J Geriatr Psychiatry 11 (2003) 62-72
41. Aschbacher K., Patterson T., von Känel R., Dimsdale J., Mills P., Adler K., et al. Coping processes and hemostatic reactivity to acute stress in dementia caregivers. Psychosom Med 67 (2005) 964-971