Polymeric nanoparticles encapsulating betamethasone phosphate with different release profiles and stealthiness

International Journal of Pharmaceutics

Volumn 375, Issue 1-2, 2009, Pages 148-154

  Ishihara, Tsutomu ^a   Kubota, Tetsushi ^a,b   Choi, Tesu ^a   Takahashi, Miyuki ^a   Ayano, Eri ^a   Kanazawa, Hideko ^b   Higaki, Megumu ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Betamethasone disodium 21 phosphate; Biodistribution; Drug release; Nanoparticles; PEG; PLA PLGA polymers

Indexed keywords

BETAMETHASONE SODIUM PHOSPHATE; MACROGOL; NANOPARTICLE; POLYGLACTIN; POLYLACTIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG RELEASE; DRUG TISSUE LEVEL; FEMALE; INTERNALIZATION; MOLECULAR WEIGHT; MOUSE; NANOENCAPSULATION; NANOPHARMACEUTICS; NONHUMAN; PARTICLE SIZE; PLASMA CLEARANCE; PRIORITY JOURNAL;

ANIMALS; BETAMETHASONE; DELAYED-ACTION PREPARATIONS; FEMALE; GLUCOCORTICOIDS; LACTIC ACID; MACROPHAGES; MICE; NANOPARTICLES; OILS; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; POLYMERS; SOLVENTS; TISSUE DISTRIBUTION; WATER;

EID: 67349157140     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.04.001     Document Type: Article

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