Stealth nanoparticles for intravenous administration

S.T.P. Pharma Sciences

Volumn 13, Issue 3, 2003, Pages 155-161

  Peracchia, M T ^a  

^a SANOFI   (France)

Author keywords

Injectable; Nanoparticles; Nanospheres; PEG; Stealth

Indexed keywords

DRUG CARRIER; LIPOSOME; MACROGOL; NANOCAPSULE; NANOPARTICLE; PROPYLENE OXIDE;

ADSORPTION; AQUEOUS SOLUTION; CHEMICAL MODIFICATION; COLLOID; COMPLEMENT ACTIVATION; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG RELEASE; DRUG TARGETING; ENCAPSULATION; FREEZE DRYING; HYDROPHOBICITY; IN VITRO STUDY; PARTICLE SIZE; PROTEIN STABILITY; REVIEW; SURFACE PROPERTY;

EID: 0042870173     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (71)

1. FRESTA M., FONTANA G., BUCOLO C., CAVALLARO G., GIAMMONA G., PUGLISI G. - Ocular tolerability and in vivo bioavailability of PEG-coated polyethyl-2-cyanoacrylate nanosphere-encapsulated acyclovir - J. Pharma. Sci., 90, 288-297, 2001.
2. TOBIO M., GREF R., SANCHEZ A., LANGER R., ALONSO M.J. - Stealth PLA-PEG nanoparticles as protein carriers for nasal administration - Pharm. Res., 15, 270-275, 1998.
3. OTSUKA H., NAGASAKI Y., KATAOKA K. - PEGylated nanoparticles for biological and pharmaceutical applications Adv. Drug Del. Rev., 55, 403-419, 2003.
4. ILLUM L., DAVIS SS. - The organ uptake of intravenously administered colloidal particles can be altered using a non-ionic surfactant (Poloxamer 338) - FEBS Lett., 167, 79-82, 1984.
5. DUNN S.E., GARNETT M.C., DAVIS SS., DAVIES M.C., ILLUM L. - In vitro cell interaction and in vivo biodistribution of poly(lactide-co-glycolide) nanospheres surface modified by poloxamer and poloxamine copolymers - J. Controlled Rel., 44, 65-76, 1997.
6. NEAL J.C., STOLNIK S., SCHACHT E., KENAWY E.R., GARNETT M.C., DAVIS S.S., ILLUM L. - In vitro displacement by rat serum of adsorbed radiolabeled poloxamer and poloxamine copolymers from model and biodegradable nanospheres - J. Pharm. Sci., 87, 1242-1248, 1998.
7. GREF R., MINAMITAKE Y., PERACCHIA M.T., TRUBETSKOY V., TORCHILIN V., LANGER R. - Biodegradable long-circulating polymeric nanospheres - Science, 263, 1600-1603, 1994.
8. BAZILE D., PRUD'HOMME C., BASSOULLET M.T., MARLARD M., SPENLEHAUER G., VEILLARD M. - Stealth Me.PEG-PLA nanoparticles avoid uptake by the mononuclear phagocytes system - J. Pharm. Sci., 84, 493-498, 1995.
9. PERACCHIA M.T., GREF R., MINAMITAKE Y., DOMB A., LOTAN N., LANGER R. - PEG-coated nanospheres from amphiphilic diblock and multiblock copolymers: investigation onf their drug encapsulation and release characteristics - J. Controlled Rel., 46, 223-231, 1997.
10. HA J.C., KIM S.Y., LEE Y.M. - Poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (Pluronic)/poly(ε-caprolactone (PCL) amphiphilic block copolymeric nanospheres. I. Preparation and characterization - J. Controlled Rel., 62, 381-392, 1999.
11. LIN W., GARNETT M.C., SCHACHT E., DAVIS S.S., ILLUM L. - Preparation and in vitro characterization of HSA-mPEG nanoparticles - Int. J. Pharm., 189, 161-170, 1999.
12. CHOI Y.K., BAE Y.H., KIM S.W. - Block copolymer nanoparticles of ethylene oxide and isobutyl cyanoacrylate - Macromeolecules, 28, 8419-8421, 1995.
13. PERACCHIA M.T., DESMAËLE D., COUVREUR P., D'ANGELO J. - Synthesis of a novel poly(MePEG cyanoacrylate-co-alkyl cyanoacrylate) amphiphilic copolymer for nanoparticle technology Macromolecules, 30, 846-851, 1997.
14. BRIGGER I. CHAMINADE P., DESMAELE D., PERACCHIA M.T., D'ANGELO J., GURNY R., RENOIR M., COUVREUR P. - Near infrared with principal components analysis as novel analytical approach for nanoparticle technology - Pharm. Res., 17, 1124-1132, 2000.
15. PERACCHIA M.T., VAUTHIER C., PUISIEUX F., COUVREUR P. - Development of sterically stabilized poly(isobutyl 2-cyanoacrylate) nanoparticles by chemical coupling of poly(ethylene glycol) - J. Biomed. Mat. Res., 34, 317-326, 1997.
16. PLARD J.P., BAZILE D. - Comparison of the safety profiles of PLA50 and Me.PEG-PLA50 nanoparticles after single dose intravenous administration to rats - Colloids and Surfaces B: Biointerfaces, 16, 173-183, 1999.
17. NAKADA Y., SAKURAI K., HORIUSHI M., TUDOMI R., NAKAMURA T., TAKAHASHI Y. - Long-circulating nanoparticles using biodegradable ABA triblock copolymers containing of poly(L-lactic acid) A-blocks attached to central poly(oxyethylene) B-blocks - Pharm. Sci., 3, 1-4, 1997.
18. MATSUMOTO J., NAKADA Y., SAKURAI K., NAKAMURA T., TAKAHASHI Y. - Preparation of nanoparticles consisted of poly(L-lactide)-poly(ethylene glycol)-poly(L-lactide) and their evaluation in vitro - Int. J. Pharm., 185, 93-101, 1999.
19. CALVO P., REMUNAN-LOPEZ C., VI LA-JATO J.L., ALONSO M.J. - Chitosan and chitosan/ethylene oxide-propylene oxide block copolymer nanoparticles as novel carriers for proteins and vaccines - Pharm. Res., 14, 1431-1436, 1997.
20. KIM I.S., JEONG Y.I., KIM S.H. - Self-assembled hydrogel nanoparticles composed of dextran and poly(ethylene glycol) macromer - Int. J. Pharm., 205, 109-116, 2000.
21. KAUL G., AMIJI M. - Long-circulating poly(ethylene glycol)-modified gelatin nanoparticles for intracellular delivery - Pharm. Res., 19, 1061-1067, 2002.
22. STOLNIK S., DAUDALI B., ARIEN A., WHETSTONE J., HEALD C.R., GARNETT M.C., DAVIS S.S., ILLUM L. - The effect of surface coverage and conformation of poly(ethylene oxide) (PEO) chains of poloxamer 407 on the biological fate of model colloidal drug carriers - Biochim. Biophys. Acta, 1514, 261-279, 2001.
23. JEON S.I., LEE J.H., ANDRADE J.D., DE GENNES P.G.Protein-surface interactions in the presence of polyethylene oxide I. Simplified theory - J. Coll. Interface. Sci., 142, 149-158, 1991.
24. PERACCHIA M.T., VAUTHIER C., PASSIRANI C., COUVREUR P., LABARRE D. - Complement consumption by poly(ethylene glycol) in different conformations chemically coupled to poly(isobutyl 2-cyanoacrylate) nanoparticles - Life Sci., 61, 749-761, 1997.
25. TORCHILIN V.P., TRUBETSKOY V.S. - Which polymers can make nanoparticulate drug carriers long circulating? - Adv. Drug Del. Rev., 16, 141-155, 1995.
26. DE GENNES P.G. - Conformations of polymers attached to an interface - Macromolecules, 13, 1069-1075, 1980.
27. KARLSTROM G., ENGKVIST O. - Theory of poly(ethylene glycol) in solution - In: Poly(ethylene glycol) Chemistry and Biological Applications, J.M. Harris and S. Zalipsky Eds., ACS Symposium Series, 1997, pp. 16-30.
28. OSTERBERG E., BERGSTROM K., HOLMBERG K., SCHUMAN T.P., RIGGS J.A., BURNS N.L., VAN ALSTINE J.M., HARRIS J.M. - Protein-rejecting ability of surface-bound dextran in end-on and side-on configurations: Comparison to PEG - J. Biomed. Mat. Res., 29, 741-747, 1995.
29. PASSIRANI C., BARRATT G., DEVISSAGUET J.Ph., LABARRE D. - Long-circulating nanoparticles bearing heparin or dextran covalently bound to poly(methyl methacrylate) - Pharm. Res., 15, 1046-1050, 1998.
30. JAULIN N., APPEL M., PASSIRANI C., BARRATT G., LABARRE D. - Reduction of te uptake by a macrophagic cell line of nanoparticles bearing heparin or dextran covalently bound to poly(methyl methacrylate) - J. Drug Targeting, 8, 165-172, 2000.
31. LIN W., GARNETT M.C., DAVIES M.C., BIGNOTTI F., FERRUTI P., DAVIS S.S., ILLUM L. - Preparation of surface-modified albumin nanospheres - Biomaterials, 18, 559-565, 1997.
32. VANDORPE J., SCHACHT E., DUNN S, HAWLEY A., STOLNIK S., DAVIS S.S., GARNETT M.C., DAVIES M.C., ILLUM L. Long-circulating biodegradable poly(phosphazene) nanoparticles surface modified with poly(phosphazene)-poly(ethylene oxide) copolymer - Biomaterials, 18, 1147-1152, 1997.
33. MOGHIMI S.M. - Chemical camouflage of nanospheres with a poorly reactive surface: towards development of stealth and target-specific nanocarriers - Biochim. Biophys. Acta, 1590, 131-139, 2002.
34. KREUTER J. - Nanoparticles - In: Colloidal Drug Delivery Systems, J. Kreuter Ed., Marcel Dekker, 1994, pp. 221-243.
35. MOSQUEIRA V.C.F., LEGRAND P., GREF R., BARRATT G. In vitro release kinetic studies of PEG-modified nanocapsules and nanospheres with a lipophilic drug: halofantrine base Proc. Int. Symp. Control. Rel. Bioact. Mater., 26, 1075-1075, 1999.
36. CAVALLI R., CAPUTO O., CARLOTTI M.E., TROTTA M., SCARNECCHIA C., GASCO M.R. - Sterilization and freeze-drying of drug-free and drug loaded solid lipid nanospheres - Int. J. Pharm., 148, 147-154, 1997.
37. PERACCHIA M.T., VAUTHIER C., DESMAËLE D., GULIK A., DEDIEU J.C., DEMOY M., D'ANGELO J., COUVREUR P. PEGylated nanoparticles from a novel methoxypolyethylene glycol cyanoacrylate-hexadecyl cyanoacrylate amphiphilic copolymer - Pharm. Res., 15, 550-556, 1998.
38. GOVENDER T., RILEY T., EHTEZAZI T., GARNETT M.C., STOLNIK S., ILLUM L., DAVIS S.S. - Defining the drug incorporation properties of PLA-PEG nanoparticles - Int. J. Pharm., 199, 95-110, 2000.
39. GREF R., QUELLEC P., SANCHEZ A., CALVO P. DELLACHERIE E., ALONSO M.J. - Development and characterization of Cya-loaded poly(lactic acid)-poly(ethylene glycol) micro- and nanoparticles. Comparison with conventional PLA particulates - Eur. J. Pharm. Biopharm., 51, 111-118, 2001.
40. QUELLEC P., GREF R., PERRIN L., DELLACHERIE E., SOMMER F., VERBAVATZ J.M., ALONSO M.J. - Protein encapsulation within polyethylene glycol-coated nanospheres. I. Physicochemical characterization - J. Biomed. Mat. Res., 42, 45-54, 1998.
41. QUELLEC P., GREF R., DELLACHERIE E., SOMMER F., TRAN M.D., ALONSO M.J. - Protein encapsulation within polyethylene glycol-coated nanospheres II. Controlled release properties - J. Biomed. Mat. Res., 47, 388-395, 1999.
42. DE JAEGHERE F., ALLEMANN E., LEROUX J.C., STEVELS W., FEIJEN J., DOELKER E., GURNY R. - Formulation and lyoprotection of poly(lactic acid-co-ethylene oxide)nanoparticles: influence on physical stability and in vitro cell uptake - Pharm. Res., 16, 859-866, 1999.
43. DE JAEGHERE F., ALLEMANN E., FEIJEN J., KISSEL T., DOELKER E., GURNY R. - Freeze-drying and lyopreservation of diblock and triblock poly(lactic acid)-poly(ethylene oxyde) (PLA-PEO) copolymer anoparticles - Pharm. Dev. Technol., 5, 473-483, 2000.
44. FRANCK M.M., FRIES L.F. - The role of complement in inflammation and phagocytosis - Imm. Today, 12, 322-326, 1991.
45. ARMSTRONG T. I, DAVIES M.C., ILLUM L. - Human serum albumin as a probe for protein adsorption to nanoparticles: relevance to biodistribution - J. Drug Targeting, 4, 389-398, 1997.
46. BLUNK T., HOCHSTRASSER D.F., SANCHEZ J.C., MÜLLER B.W., MÜLLER R.H. - Colloidal carriers for intravenous drug targeting: plasma protein adsorption patterns on surface-modified latex particles evaluated by two-dimensional polyacrylamide gel electrophoresis - Electrophoresis, 14, 1382-1387, 1993.
47. PERACCHIA M.T., HARNISCH S., PINTO-ALPHANDARY H., GULIK A., DEDIEU J.C., DESMAËLE D., D'ANGELO J., MÜLLER R.H., COUVREUR P. - Visualization of in vitro protein-rejecting properties of PEGylated stealth polycyanoacrylate nanoparticles - Biomaterials, 20, 1269-1275, 1999.
48. KAZATCHKINE M.D., CARRENO M.P. - Activation of the complement system at the interface between blood and artificial surfaces - Biomaterials, 9, 30-35, 1988.
49. VITTAZ M., BAZILE D., SPENLEHAUER G., VERRECCHIA T., VEILLARD M., PUISIEUX F., LABARRE D. - Effect of PEO surface density on long-circulating PLA-PEO nanoparticles which are very low complement activators - Biomaterials, 17, 1575-1581, 1996.
50. MOSQUEIRA V.C.F., LEGRAND P., GULIK A., BOURDON O., GREF R., LABARRE D., BARRATT G. - Relationship between complement activation, cellular uptake and surface physicochemical aspects of novel PEG-modified nanocapsules Biomaterials, 22, 2967-2979, 2001.
51. DE JAEGHERE F., ALLEMANN E., FEIJEN J., KISSEL T., DOELKER E., GURNY R. - Cellular uptake of PEO surface-modified nanoparticles: evaluation of nanoparticles made of PLA:PEO diblock and triblock copolymers - J. Drug Targeting, 8, 143-153, 2000.
52. ZAMBAUX M.F., FAIVRE-FIORINA B., BONNEAUX F., MARCHAL S., MERLIN J.L., DELLACHERIE E., LABRUDE P., VIGNERON C. - Involvement of neutrophilic granulocytes in the uptake of biodegradable non-stealth and stealth nanoparticles in guinea pig - Biomaterials, 21, 975-980, 2000.
53. PERACCHIA M.T., FATTAL E., DESMAËLE D., BESNARD M., NOËL J.P., GOMIS J.M., APPEL M., D'ANGELO J., COUVREUR P. - Stealth PEGylated nanoparticles for intravenous administration and splenic targeting - J. Controlled Rel., 60, 121-128, 1999.
54. MOGHIMI S.M. - Re-establishing the long circulatory behaviour of poloxamine-coated particles after repeated intravenous administration: applications in cancer drug delivery and imaging Biochim. Biophys. Acta, 1472, 399-403, 1999.
55. PANAGI Z., BELETSI A., EVANGELATOS G., LIVANIOUS E., ITHAKISSIOS D.S., AVGOUSTAKIS K. - Effect of dose on the biodistribution and pharmacokinetics of PLGA and PLGA-mPEG nanoparticles - Int. J. Pharm., 221, 143-152, 2001.
56. GULYAEV A.E., GELPERINA S.E., SKIDAN I.N., ANTROPOV A.S., KIVMAN G.Y., KREUTER J. - Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles - Pharm. Res., 16, 1564-1569, 1999.
57. KREUTER J., ALYAUTDIN R.N. - Using nanoparticles to target drugs to the central nervous system - In: Blood-Brain Barrier and Drug Delivery to the CNS, D.J. Begley, M.W. Bradbury, J. Kreuter Eds., Marcel Dekker Inc., NY, 2000, pp. 205-223.
58. CALVO P., GOURITIN B., CHACUN H., DESMAËLE D., D'ANGELO J., NOËL J.P., GEORGIN D., FATTAL E., ANDREUX J.P., COUVREUR P. - Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery - Pharm. Res., 18, 1157-1166, 2001.
59. OLIVIER J.C., FENART L., CHAUVET R., PARIAT C., CECCHELLI R., COUET W. - Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity - Pharm. Res., 16, 1836-1842, 1999.
60. CALVO P., GOURITIN B., VILLARROYA H., ECLANCHER F., GIANNAVOLA C., KLEIN C., ANDREUX J.P., COUVREUR P. - Quantification and localization of PEGylated polycyanocrylate nanoparticles in brain and spinal cord during experimental allergic encephalomyelitis in the rat - Eur. J. Neurosci., 15, 1317-1326, 2002.
61. PODIO V., ZARA G.P., CARAZZONE M., CAVALLI R., GASCO M.R. - Biodistribution of stealth and non-stealth solid lipid nanospheres after intravenous administration in rats - J. Pharm. Pharmacol., 52, 1057-1063, 2000.
62. MAURER N., FENSKE D.B., CULLIS P.R. - Developments in liposomal drug delivery systems - Expert Opin. Biol. Ther., 1, 1-25, 2001.
63. BOUREL D., ROLLAND A., LE VERGE R., GENETET B. - A new immunoreagent for cell labeling. CD3 monoclonal antibody covalently coupled to fluorescent polymethacrylic nanoparticles - J. Immunol. Meth., 106, 161-167, 1988.
64. STELLA B., ARPICCO S., PERACCHIA M.T., DESMAËLE D., HOEBEKE J., RENOIR M., D'ANGELO J., CATTEL L., COUVREUR P. - Design of folic acid-conjugated nanoparticles fpr drug targeting - J. Pharm. Sci., 89, 1452-1464, 2000.
65. ALLÉMANN E., BRASSEUR N., BENREZZAK O., ROUSSEAU J., KUDREVICH S.V., BOYLE R.W., LEROUX J.C., GURNY R., VAN LIER J.E. - PEG-coated poly(lactic acid) nanoparticles for the delivery of hexadecafluoro zinc phthalocyanine to EMT-6 mouse mammary tumors - J. Pharm. Pharmacol., 47, 382-387, 1995.
66. LI Y.P., PEI Y.Y., ZHOU Z.H., ZHANG X.Y., GU Z.H., DING J., ZHOU J.J., GAO X.J., ZHU J.H. - Stealth polycyanoacrylate nanoparticles as tumor necrosis factor-α carriers: pharmacokinetics and anti-tumor effects - Biol. Pharm. Bull., 24, 662-665, 2001.
67. FUNDARO A., CAVALLI R., BARGONI A., VIGHETTO D., ZARA G.P., GASCO M.R. - Non-stealth and stealth solid lipid nanoparticles carrying doxorubicin: pharmacokinetics and tissue distribution after iv administration to rats - Pharmacol. Res., 42, 337-343, 2000.
68. ZARA G.P., CAVALLI R., BARGONI A., FUNDARO A., VIGHETTO D., GASCO M.R. - Intravenous administration to rabbits of non-stealth and stealth doxorubicin-loaded solid lipid nanoparticles - J. Drug Targeting, 10, 327-335, 2002.
69. CHEN D.B., YANG T.Z., LU W.L., ZHANG Q. - In vitro and in vivo study of two types of long-circulating solid lipid nanoparticles containing paclitaxel - Chem. Pharm. Bull., 49, 1444-1447, 2001.
70. MOLINA J., URBINA J., GREF R., BRENER Z., RODRIGUES Jr. J.M. - Cure of experimental Chagas' disease by the bistriazole DO870 incorporated into "stealth" polyethyleneglycolpolylactide nanospheres - J. Antimicrob. Chem., 47, 101-104, 2001.
71. CALVO P., GOURITIN B., BRIGGER I., LASMEZAS C., DESLYS J.P., WILLIAMS A., ANDREUX J.P., DORMONT D., COUVREUR P. - PEGylated nanoparticles as vector for drug delivery in prion diseases - J. Neuroscience Meth., 111, 151-155, 2001.