메뉴 건너뛰기




Volumn 8, Issue 8, 2009, Pages 697-701

Glutathione: A key player in autoimmunity

Author keywords

Glutathione; GSH; Immunology; Oxidative stress; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; AURANOFIN; AUROTHIOMALATE; CATALASE; GLUTAMINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; THIOCTIC ACID;

EID: 67349146993     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2009.02.020     Document Type: Review
Times cited : (168)

References (40)
  • 2
    • 42949154359 scopus 로고    scopus 로고
    • The interrelation of glutathione reductase, catalase, glutathione peroxidase, superoxide dismutase, and glucose-6-phosphate in the pathogenesis of rheumatoid arthritis
    • Kalpakcioglu B., and Senel K. The interrelation of glutathione reductase, catalase, glutathione peroxidase, superoxide dismutase, and glucose-6-phosphate in the pathogenesis of rheumatoid arthritis. Clin Rheumatol 27 (2008) 141-145
    • (2008) Clin Rheumatol , vol.27 , pp. 141-145
    • Kalpakcioglu, B.1    Senel, K.2
  • 4
    • 0027300736 scopus 로고
    • Lipid peroxidation: its mechanism, measurement, and significance
    • Halliwell B., and Chirico S. Lipid peroxidation: its mechanism, measurement, and significance. Am J Clin Nutr 57 (1993) 715S-724S
    • (1993) Am J Clin Nutr , vol.57
    • Halliwell, B.1    Chirico, S.2
  • 5
    • 0031002446 scopus 로고    scopus 로고
    • Correlation between blood antioxidant levels and lipid peroxidation in rheumatoid arthritis
    • Gambhir J.K., Lali P., and Jain A.K. Correlation between blood antioxidant levels and lipid peroxidation in rheumatoid arthritis. Clin Biochem 30 (1997) 351-355
    • (1997) Clin Biochem , vol.30 , pp. 351-355
    • Gambhir, J.K.1    Lali, P.2    Jain, A.K.3
  • 6
    • 58749104550 scopus 로고    scopus 로고
    • Metabolic control of T cell activation and death in SLE
    • Fernandez D., and Perl A. Metabolic control of T cell activation and death in SLE. Autoimmun Rev 8 (2009) 184-189
    • (2009) Autoimmun Rev , vol.8 , pp. 184-189
    • Fernandez, D.1    Perl, A.2
  • 8
    • 50949132714 scopus 로고    scopus 로고
    • Reactive oxygen species generation at the plasma membrane for antibody control
    • Crane F.L., and Low H. Reactive oxygen species generation at the plasma membrane for antibody control. Autoimmun Rev 7 (2008) 518-522
    • (2008) Autoimmun Rev , vol.7 , pp. 518-522
    • Crane, F.L.1    Low, H.2
  • 9
    • 50949092229 scopus 로고    scopus 로고
    • Prologue to autoimmunity forum: autoimmunity reviews on redox signaling
    • Faulk W.P., and McIntyre J.A. Prologue to autoimmunity forum: autoimmunity reviews on redox signaling. Autoimmun Rev 7 (2008) 515-517
    • (2008) Autoimmun Rev , vol.7 , pp. 515-517
    • Faulk, W.P.1    McIntyre, J.A.2
  • 10
    • 0037505644 scopus 로고    scopus 로고
    • Analysis of glutathione: implication in redox and detoxification
    • Pastore A., Federici G., Bertini E., and Piemonte F. Analysis of glutathione: implication in redox and detoxification. Clin Chim Acta 333 (2003) 19-39
    • (2003) Clin Chim Acta , vol.333 , pp. 19-39
    • Pastore, A.1    Federici, G.2    Bertini, E.3    Piemonte, F.4
  • 11
    • 0028029457 scopus 로고
    • Functions of glutathione and glutathione disulfide in immunology and immunopathology
    • Dröge W., Schulze-Osthoff K., Mihm S., Galter D., Schenk H., Eck H.P., et al. Functions of glutathione and glutathione disulfide in immunology and immunopathology. FASEB J 8 (1994) 1131-1138
    • (1994) FASEB J , vol.8 , pp. 1131-1138
    • Dröge, W.1    Schulze-Osthoff, K.2    Mihm, S.3    Galter, D.4    Schenk, H.5    Eck, H.P.6
  • 12
    • 18344390036 scopus 로고    scopus 로고
    • Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes
    • Fratelli M., Demol H., Puype M., Casagrande S., Eberini I., Salmona M., et al. Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes. Proc Natl Acad Sci U S A 99 (2002) 3505-3510
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3505-3510
    • Fratelli, M.1    Demol, H.2    Puype, M.3    Casagrande, S.4    Eberini, I.5    Salmona, M.6
  • 13
    • 0032874845 scopus 로고    scopus 로고
    • Glutathione and glutathione-dependent enzymes represent a coordinately regulated defence against oxidative stress
    • Hayes J.D., and McLellan L.I. Glutathione and glutathione-dependent enzymes represent a coordinately regulated defence against oxidative stress. Free Radic Res 31 (1999) 273-300
    • (1999) Free Radic Res , vol.31 , pp. 273-300
    • Hayes, J.D.1    McLellan, L.I.2
  • 14
    • 0033975215 scopus 로고    scopus 로고
    • The potential use of glutathionyl haemoglobin as a clinical marker of oxidative stress
    • Bursell S.E., and King G.L. The potential use of glutathionyl haemoglobin as a clinical marker of oxidative stress. Clin Chem 46 (2000) 145-146
    • (2000) Clin Chem , vol.46 , pp. 145-146
    • Bursell, S.E.1    King, G.L.2
  • 15
  • 16
    • 0022512449 scopus 로고
    • Glutathione augments the activation of cytotoxic T lymphocytes in vivo
    • Droge W., Pottmeyer-Gerber C., Schmidt H., and Nick S. Glutathione augments the activation of cytotoxic T lymphocytes in vivo. Immunobiology 172 (1986) 151-156
    • (1986) Immunobiology , vol.172 , pp. 151-156
    • Droge, W.1    Pottmeyer-Gerber, C.2    Schmidt, H.3    Nick, S.4
  • 17
    • 0026002718 scopus 로고
    • Differential effects of glutathione depletion on T cell subsets
    • Gmunder H., and Droge W. Differential effects of glutathione depletion on T cell subsets. Cell Immunol 138 (1991) 229-237
    • (1991) Cell Immunol , vol.138 , pp. 229-237
    • Gmunder, H.1    Droge, W.2
  • 18
    • 0025677250 scopus 로고
    • Intracellular thiols regulate activation of nuclear factor kB and transcription of immunodeficiency virus
    • Staal F.J., Roederer M., Herzenberg L.A., and Herzenberg L.A. Intracellular thiols regulate activation of nuclear factor kB and transcription of immunodeficiency virus. Proc Natl Acad Sci U S A 87 (1990) 9943-9947
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 9943-9947
    • Staal, F.J.1    Roederer, M.2    Herzenberg, L.A.3    Herzenberg, L.A.4
  • 19
    • 0028902123 scopus 로고
    • Modulation of transcription factor NF-kB activity by intracellular glutathione levels and by variations of the extracellular cysteine supply
    • Mihm S., Galter D., and Droge W. Modulation of transcription factor NF-kB activity by intracellular glutathione levels and by variations of the extracellular cysteine supply. FASEB J 9 (1995) 246-252
    • (1995) FASEB J , vol.9 , pp. 246-252
    • Mihm, S.1    Galter, D.2    Droge, W.3
  • 20
    • 1842298691 scopus 로고    scopus 로고
    • Thiol modulation inhibits the interleukin-1-mediated activation of an IL-1 receptor associated protein kinase and NF-kB
    • Tewes F., Bol G.F., and Brigelius-Flohe R. Thiol modulation inhibits the interleukin-1-mediated activation of an IL-1 receptor associated protein kinase and NF-kB. Eur J Immunol 27 (1997) 3015-3022
    • (1997) Eur J Immunol , vol.27 , pp. 3015-3022
    • Tewes, F.1    Bol, G.F.2    Brigelius-Flohe, R.3
  • 21
    • 0033231351 scopus 로고    scopus 로고
    • Gene expression and the thiol redox state
    • Arrigo A.P. Gene expression and the thiol redox state. Free Radic Biol Med 27 (1999) 936-944
    • (1999) Free Radic Biol Med , vol.27 , pp. 936-944
    • Arrigo, A.P.1
  • 22
    • 34247535550 scopus 로고    scopus 로고
    • Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence
    • Kim H.J., Barajas B., Chan R.C., and Nel A.E. Glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: implications for systemic disease and immunosenescence. J Allergy Clin Immunol 119 (2007) 1225-1233
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 1225-1233
    • Kim, H.J.1    Barajas, B.2    Chan, R.C.3    Nel, A.E.4
  • 23
    • 0342894773 scopus 로고    scopus 로고
    • Reoxygenation of hypoxic human umbilical vein endothelial cells activates the classic complement pathway
    • Collard C.D., Vakeva A., Bukusoglu C., Zund G., Sperati C.J., Colgan S.P., et al. Reoxygenation of hypoxic human umbilical vein endothelial cells activates the classic complement pathway. Circulation 96 (1997) 326-333
    • (1997) Circulation , vol.96 , pp. 326-333
    • Collard, C.D.1    Vakeva, A.2    Bukusoglu, C.3    Zund, G.4    Sperati, C.J.5    Colgan, S.P.6
  • 24
    • 0031811414 scopus 로고    scopus 로고
    • Complement activation following reoxygenation of hypoxic human endothelial cells: role of intracellular reactive oxygen species, NF-kB and new protein synthesis
    • Collard C.D., Agah A., and Stahl G.L. Complement activation following reoxygenation of hypoxic human endothelial cells: role of intracellular reactive oxygen species, NF-kB and new protein synthesis. Immunopharmacology 39 (1998) 39-50
    • (1998) Immunopharmacology , vol.39 , pp. 39-50
    • Collard, C.D.1    Agah, A.2    Stahl, G.L.3
  • 25
    • 0026538733 scopus 로고
    • Activation of the fifth component of human complement by oxygen-derived free radicals and by methionine oxidizing agents: a comparison
    • Vogt W., and Hesse D. Activation of the fifth component of human complement by oxygen-derived free radicals and by methionine oxidizing agents: a comparison. Immunobiology 184 (1992) 384-391
    • (1992) Immunobiology , vol.184 , pp. 384-391
    • Vogt, W.1    Hesse, D.2
  • 26
    • 0030789179 scopus 로고    scopus 로고
    • The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents
    • Wilhelm D., Bender K., Knebel A., and Angel P. The level of intracellular glutathione is a key regulator for the induction of stress-activated signal transduction pathways including Jun N-terminal protein kinases and p38 kinase by alkylating agents. Mol Cell Biol 17 (1997) 4792-4800
    • (1997) Mol Cell Biol , vol.17 , pp. 4792-4800
    • Wilhelm, D.1    Bender, K.2    Knebel, A.3    Angel, P.4
  • 27
    • 0036721605 scopus 로고    scopus 로고
    • Complement activates the c-jun N-terminal kinase/stress-activated protein kinase in glomerular epithelial cells
    • Peng H., Takano T., Papillon J., Bijian K., Khadir A., and Cybulsky A.V. Complement activates the c-jun N-terminal kinase/stress-activated protein kinase in glomerular epithelial cells. J Immunol 169 (2002) 2594-2601
    • (2002) J Immunol , vol.169 , pp. 2594-2601
    • Peng, H.1    Takano, T.2    Papillon, J.3    Bijian, K.4    Khadir, A.5    Cybulsky, A.V.6
  • 28
    • 0037733975 scopus 로고    scopus 로고
    • The importance of glutathione in human disease
    • Townsend D.M., Tew K.D., and Tapiero H. The importance of glutathione in human disease. Biomed Pharmacother 57 (2003) 145-155
    • (2003) Biomed Pharmacother , vol.57 , pp. 145-155
    • Townsend, D.M.1    Tew, K.D.2    Tapiero, H.3
  • 29
    • 50949107996 scopus 로고    scopus 로고
    • Autoimmune thyroiditis and ROS
    • Burek C.L., and Rose N.R. Autoimmune thyroiditis and ROS. Autoimmun Rev 7 (2008) 530-537
    • (2008) Autoimmun Rev , vol.7 , pp. 530-537
    • Burek, C.L.1    Rose, N.R.2
  • 30
    • 50949105388 scopus 로고    scopus 로고
    • Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease?
    • Griffiths H.R. Is the generation of neo-antigenic determinants by free radicals central to the development of autoimmune rheumatoid disease?. Autoimmun Rev 7 (2008) 544-549
    • (2008) Autoimmun Rev , vol.7 , pp. 544-549
    • Griffiths, H.R.1
  • 31
    • 50949098933 scopus 로고    scopus 로고
    • Autoimmunity and oxidatively modified autoantigens
    • Kurien B.T., and Scofield R.H. Autoimmunity and oxidatively modified autoantigens. Autoimmun Rev 7 (2008) 567-573
    • (2008) Autoimmun Rev , vol.7 , pp. 567-573
    • Kurien, B.T.1    Scofield, R.H.2
  • 32
    • 0031065210 scopus 로고    scopus 로고
    • Evidence for the role of an altered redox state in hyporesponsiveness of synovial T cells in rheumatoid arthritis
    • Maurice M.M., Nakamura H., van der Voort E.A., van Vliet A.I., Staal F.J., Tak P.P., et al. Evidence for the role of an altered redox state in hyporesponsiveness of synovial T cells in rheumatoid arthritis. J Immunol 158 (1997) 1458-1465
    • (1997) J Immunol , vol.158 , pp. 1458-1465
    • Maurice, M.M.1    Nakamura, H.2    van der Voort, E.A.3    van Vliet, A.I.4    Staal, F.J.5    Tak, P.P.6
  • 34
    • 0024378711 scopus 로고
    • Systemic glutathione deficiency in symptom-free HIV seropositive individuals
    • Buhl R., Jaffe H.A., Holroyd K.J., Wells F.B., Mastrangeli A., Saltini C., et al. Systemic glutathione deficiency in symptom-free HIV seropositive individuals. Lancet 2 (1989) 1294-1298
    • (1989) Lancet , vol.2 , pp. 1294-1298
    • Buhl, R.1    Jaffe, H.A.2    Holroyd, K.J.3    Wells, F.B.4    Mastrangeli, A.5    Saltini, C.6
  • 35
    • 50949112988 scopus 로고    scopus 로고
    • Oxidation of LDL and its clinical implication
    • Matsuura E., Hughes G.R., and Khamashta M.A. Oxidation of LDL and its clinical implication. Autoimmun Rev 7 (2008) 558-566
    • (2008) Autoimmun Rev , vol.7 , pp. 558-566
    • Matsuura, E.1    Hughes, G.R.2    Khamashta, M.A.3
  • 36
    • 0032521155 scopus 로고    scopus 로고
    • Glutathione in human plasma: decline in association with ageing, age-related macular degeneration, and diabetes
    • Samiec P.S., Drews-Botsch C., Flagg E.W., Kurtz J.C., Sternberg Jr. P., Reed R.L., et al. Glutathione in human plasma: decline in association with ageing, age-related macular degeneration, and diabetes. Free Radic Biol Med 24 (1998) 699-704
    • (1998) Free Radic Biol Med , vol.24 , pp. 699-704
    • Samiec, P.S.1    Drews-Botsch, C.2    Flagg, E.W.3    Kurtz, J.C.4    Sternberg Jr., P.5    Reed, R.L.6
  • 37
    • 1942489724 scopus 로고    scopus 로고
    • Oxidative stress and nutritional prevention in autoimmune rheumatic diseases
    • Sukkar S.G., and Rossi E. Oxidative stress and nutritional prevention in autoimmune rheumatic diseases. Autoimmun Rev 3 (2004) 199-206
    • (2004) Autoimmun Rev , vol.3 , pp. 199-206
    • Sukkar, S.G.1    Rossi, E.2
  • 39
    • 0035132163 scopus 로고    scopus 로고
    • The glutathione defense system in the pathogenesis of rheumatoid arthritis
    • Hassan M.Q., Hadi R.A., Al-Rawi Z.S., Padron V.A., and Stohs S.J. The glutathione defense system in the pathogenesis of rheumatoid arthritis. J Appl Toxicol 21 (2001) 69-73
    • (2001) J Appl Toxicol , vol.21 , pp. 69-73
    • Hassan, M.Q.1    Hadi, R.A.2    Al-Rawi, Z.S.3    Padron, V.A.4    Stohs, S.J.5
  • 40
    • 56349114121 scopus 로고    scopus 로고
    • Antioxidants and smoking in autoimmune disease-opposing sides of the seesaw?
    • Zifman E., Amital H., Gilburd B., and Shoenfeld Y. Antioxidants and smoking in autoimmune disease-opposing sides of the seesaw?. Autoimmun Rev 8 (2008) 165-169
    • (2008) Autoimmun Rev , vol.8 , pp. 165-169
    • Zifman, E.1    Amital, H.2    Gilburd, B.3    Shoenfeld, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.