Protective role of estrogen receptor-alpha on lower chlorinated PCB congener-induced DNA damage and repair in human tumoral breast cells

Toxicology Letters

Volumn 188, Issue 1, 2009, Pages 11-19

  Lin, Chia Hua ^a   Huang, Ching Lung ^a   Chuang, Ming Chieh ^a   Wang, Ying Jan ^b   Chen, Dar Ren ^c   Chen, Shou Tung ^c   Lin, Po Hsiung ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

Author keywords

Oxidative stress; PARP 1 activation; PCBs

Indexed keywords

2,2',5,5' TETRACHLOROBIPHENYL; 3,3',4,4' TETRACHLOROBIPHENYL; BIPHENYL DERIVATIVE; CASPASE; ESTROGEN RECEPTOR ALPHA; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYCHLORINATED BIPHENYL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CELL; CANCER CELL; CANCER CELL CULTURE; CARCINOGENESIS; CELL LINE; CELL PROTECTION; CELL STRAIN MCF 7; CHLORINATION; CONCENTRATION (PARAMETERS); CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL;

APOPTOSIS; BREAST NEOPLASMS; CARCINOGENS, ENVIRONMENTAL; CASPASES; CELL LINE, TUMOR; CELL SURVIVAL; CYTOPROTECTION; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE; HUMANS; MOLECULAR STRUCTURE; NADP; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; POLYCHLORINATED BIPHENYLS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR SUPPRESSOR PROTEIN P53;

EID: 67349146745     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.02.009     Document Type: Article

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