Genotoxic activation of the environmental pollutant 3,6-dinitrobenzo[e]pyrene in Salmonella typhimurium umu strains expressing human cytochrome P450 and N-acetyltransferase

Toxicology Letters

Volumn 188, Issue 3, 2009, Pages 258-262

  Oda, Yoshimitsu ^a   Hirayama, Teruhisa ^b   Watanabe, Tetsushi ^b  

^a Faculty of Science   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

3,6 Dinitrobenzo e pyrene; Genotoxic activation; Human cytochrome P450; Human O acetyltransferase; SOS umu assay

Indexed keywords

3,6 DINITROBENZO[E]PYRENE; ACYLTRANSFERASE; CYTOCHROME P450; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 1B1; CYTOCHROME P450 3A4; MUTAGENIC AGENT; NITROREDUCTASE; PYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; GENE EXPRESSION; GENOTOXICITY; JAPAN; METABOLIC ACTIVATION; NONHUMAN; POLLUTANT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REDUCTION; SALMONELLA TYPHIMURIUM; SURFACE SOIL;

ACETYLTRANSFERASES; BENZO(A)PYRENE; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; HUMANS; MUTAGENS; NITROREDUCTASES; SALMONELLA TYPHIMURIUM; SOIL POLLUTANTS;

BACTERIA (MICROORGANISMS); SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SALMONELLA TYPHIMURIUM;

EID: 67349146731     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2009.04.010     Document Type: Article

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