Semi-mechanistic pharmacodynamic modelling of gene expression and silencing processes

European Journal of Pharmaceutical Sciences

Volumn 37, Issue 3-4, 2009, Pages 418-426

  Berraondo, Pedro ^a   González Aseguinolaza, Gloria ^a   Trocóniz, Iñaki F ^b  

^a UNIVERSITY OF NAVARRA   (Spain)

^b UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Gene expression and silencing; Gene therapy; Interferon ; NONMEM; Semi mechanistic modelling

Indexed keywords

ALPHA INTERFERON; BETA GALACTOSIDASE; LUCIFERASE; PLASMID DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA TRANSCRIPTION; FEMALE; GENE CASSETTE; GENE DELIVERY SYSTEM; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TRANSFER; GENETIC MODEL; IN VIVO STUDY; MOUSE; NON INVASIVE PROCEDURE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TRANSGENE;

ALGORITHMS; ANIMALS; BETA-GALACTOSIDASE; CHROMATOGRAPHY, THIN LAYER; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; GENE SILENCING; GENE THERAPY; INTERFERON-ALPHA; LUCIFERASES; LUMINESCENCE; MICE; MICE, INBRED BALB C; MODELS, GENETIC; PLASMIDS;

EID: 67349145996     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2009.03.013     Document Type: Article

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