Tumor specific cytotoxicity of β-glucosylceramide: Structure-cytotoxicity relationship and anti-tumor activity in vivo

Cancer Chemotherapy and Pharmacology

Volumn 64, Issue 3, 2009, Pages 485-496

  Oku, Hirosuke ^a   Li, Changchun ^a   Shimatani, Masayuki ^a   Iwasaki, Hironori ^a   Toda, Takayoshi ^b   Okabe, Takafumi ^a   Watanabe, Hisami ^a  

^a UNIVERSITY OF THE RYUKYUS   (Japan)

^b UNIVERSITY HOSPITAL OF THE RYUKYUS   (Japan)

Author keywords

Antitumor immunity; Cytotoxicity; Glucosylceramide; Structure activity relationship; Tumor selective

Indexed keywords

BETA GALACTOSYLCERAMIDE; BETA GLUCOSYLCERAMIDE; GLUCOSYLCERAMIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SELECTIVITY; HUMAN; HUMAN CELL; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; GLUCOSYLCERAMIDES; HUMANS; HYDROPHOBICITY; INJECTIONS, INTRAPERITONEAL; LYMPHOMA; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; NATURAL KILLER T-CELLS; NECROSIS; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NEOPLASMS; REACTIVE OXYGEN SPECIES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67349136815     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0896-2     Document Type: Article

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