Autophagy and the functional roles of Atg5 and beclin-1 in the anti-tumor effects of 3β androstene 17α diol neuro-steroid on malignant glioma cells

Journal of Steroid Biochemistry and Molecular Biology

Volumn 115, Issue 3-5, 2009, Pages 137-145

  Graf, Martin R ^a   Jia, Wentao ^a   Johnson, Ross S ^b   Dent, Paul ^a   Mitchell, Clint ^a   Loria, Roger M ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

^b CHICAGO STATE UNIVERSITY   (United States)

Author keywords

Androstene neuro steroids; Atg5; Autophagy; Beclin 1; Malignant glioma

Indexed keywords

3 METHYLADENINE; 3BETA ANDROSTENE 17ALPHA DIOL; ANDROSTANE DERIVATIVE; ATG5 PROTEIN; BAFILOMYCIN A1; BECLIN 1; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NEUROSTEROID; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; CANCER CELL; CELL DEATH; CELL ORGANELLE; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; GENE SILENCING; GLIOMA; HUMAN; HUMAN CELL; IC 50; RNA INTERFERENCE;

ANABOLIC AGENTS; ANDROSTANE-3,17-DIOL; ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL LINE, TUMOR; GLIOMA; HUMANS; MEMBRANE PROTEINS; MICE; MICROTUBULE-ASSOCIATED PROTEINS; ORGANELLES; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 67349131327     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2009.03.013     Document Type: Article

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