Cisplatin-induced nitrosylation of p53 prevents its mitochondrial translocation

Free Radical Biology and Medicine

Volumn 46, Issue 12, 2009, Pages 1607-1613

  Hernlund, Emma ^a   Kutuk, Ozgur ^b   Basaga, Huveyda ^b   Linder, Stig ^a   Panaretakis, Theocharis ^a   Shoshan, Maria ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SABANCI UNIVERSITY   (Turkey)

Author keywords

Free radicals; Mitochondria; Nitrotyrosine; p53; Platinum chemotherapy; Subcellular localization

Indexed keywords

CISPLATIN; INDUCIBLE NITRIC OXIDE SYNTHASE; OXALIPLATIN; PLATINOL R; PROTEIN BCL XL; PROTEIN P53; UNCLASSIFIED DRUG;

ARTICLE; HUMAN; HUMAN CELL; MITOCHONDRION; NITROSYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION;

AMIDINES; BENZYLAMINES; CISPLATIN; HUMANS; MITOCHONDRIA; NITRIC OXIDE SYNTHASE TYPE II; ORGANOPLATINUM COMPOUNDS; PROTEIN TRANSPORT; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; TYROSINE;

EID: 67349122098     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.03.015     Document Type: Article

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