Hypothalamic preproghrelin gene expression is repressed by insulin via both PI3-K/Akt and ERK1/2 MAPK pathways in immortalized, hypothalamic neurons

Neuroendocrinology

Volumn 89, Issue 3, 2009, Pages 267-275

  Fick, L J ^a   Cai, F ^a   Belsham, D D ^a,b,c  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Hypothalamic cell lines; Insulin signaling; Neurons; Preproghrelin; Transcription

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; GHRELIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PREPROGHRELIN; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HYPOTHALAMUS; MOUSE; NONHUMAN; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; CHROMONES; DOWN-REGULATION; FLAVONOIDS; GHRELIN; HYPOTHALAMUS; INSULIN; MAP KINASE KINASE KINASES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; NEURONS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, INSULIN;

EID: 67349097700     PISSN: 00283835     EISSN: None     Source Type: Journal    
DOI: 10.1159/000167698     Document Type: Article

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