Substrate-dependent modulation of enzyme activity by allosteric effector antibodies

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1794, Issue 8, 2009, Pages 1259-1268

  Barlow, John N ^a   Conrath, Katja ^a   Steyaert, Jan ^a  

^a FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

Allosteric effector; Enzyme inhibition; Kinetic mechanism; Nucleoside hydrolase; VHH domain antibody

Indexed keywords

ANTIBODY; NUCLEOSIDASE; RIBOSE;

ALLOSTERISM; ANTIGEN BINDING; ARTICLE; CATALYSIS; CHEMICAL BOND; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MODIFICATION; HEAVY CHAIN; INHIBITION KINETICS; NONHUMAN; PRIORITY JOURNAL; TRYPANOSOMA VIVAX;

ALLOSTERIC REGULATION; ANIMALS; CATALYSIS; IMMUNOGLOBULIN VARIABLE REGION; KINETICS; N-GLYCOSYL HYDROLASES; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; PURINE NUCLEOSIDES; PYRIMIDINONES; TRYPANOSOMA VIVAX;

TRYPANOSOMA VIVAX;

EID: 67349089888     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbapap.2009.03.019     Document Type: Article

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