Nicotine promotes colon tumor growth and angiogenesis through β-adrenergic activation

Toxicological Sciences

Volumn 97, Issue 2, 2007, Pages 279-287

  Wong, Helen Pui Shan ^a   Yu, Le ^b   Lam, Emily Kai Yee ^a   Tai, Emily Kin Ki ^a   Wu, William Ka Kei ^b   Cho, Chi Hin ^b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

adrenoceptors; Colon cancer; Nicotine; Smoking

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ADRENALIN; ATENOLOL; BETA ADRENERGIC RECEPTOR; CIGARETTE SMOKE; COTININE; CYCLOOXYGENASE 2; NICOTINE; PROSTAGLANDIN E2; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; BETA ADRENERGIC STIMULATION; CANCER INHIBITION; CIGARETTE SMOKING; COLON CARCINOGENESIS; COLON TUMOR; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GENE EXPRESSION; MOUSE; NONHUMAN; NUDE MOUSE; TUMOR GROWTH; TUMOR VASCULARIZATION; TUMOR XENOGRAFT;

ADRENERGIC BETA-AGONISTS; ANIMALS; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; COLONIC NEOPLASMS; COTININE; CYCLOOXYGENASE 2; DINOPROSTONE; EPINEPHRINE; HT29 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; NICOTINE; NICOTINIC AGONISTS; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MUS MUSCULUS; NICOTIANA TABACUM;

EID: 34447562804     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm060     Document Type: Article

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