Crocetin attenuates norepinephrine-induced cytotoxicity in primary cultured rat cardiac myocytes by antioxidant in vitro

Journal of Asian Natural Products Research

Volumn 11, Issue 5, 2009, Pages 417-425

  Shen, Xiang Chun ^a,b   Qian, Zhi Yu ^c   Wang, Ya Juan ^c   Duan, Jin Ao ^b  

^a GUIZHOU MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Cardiac myocytes; Crocetin; Intracellular Ca2+; Norepinephrine; Oxidative stress

Indexed keywords

CALCIUM ION; CROCETIN; CYTOCHROME C; GLUTATHIONE; GLUTATHIONE REDUCTASE; NORADRENALIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; ANTIOXIDANT; CALCIUM; CAROTENOID;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL LEVEL; CELL PROTECTION; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; HEART MUSCLE CELL; LIPID PEROXIDATION; NEWBORN; NONHUMAN; OXIDATIVE STRESS; RAT; ANIMAL; CHEMICAL STRUCTURE; DRUG EFFECT; METABOLISM; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; APOPTOSIS; CALCIUM; CAROTENOIDS; GLUTATHIONE; LIPID PEROXIDATION; MOLECULAR STRUCTURE; MYOCYTES, CARDIAC; NOREPINEPHRINE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 67149146700     PISSN: 10286020     EISSN: 14772213     Source Type: Journal    
DOI: 10.1080/10286020902858838     Document Type: Article

References (25)

1. Y. Xiang and B.K. Kobilka, Science 300, 1530 (2003).
2. F. Qin, J. Shite, and C.S. Liang, Am. J. Physiol. Heart Circ. Physiol. 285, H822 (2003).
3. Y.C. Fu, C.S. Chi, S.C. Yin, B. Hwang, Y.T. Chiu, and S.L. Hsu, Cardiovasc. Res. 62, 558 (2004).
4. N. Li and Y.W. Kwan, J. Chromatogr. A 849, 349 (1999).
5. G.L. Xu, Z.N. Gong, W.P. Yu, L. Gao, S.Y. He, and Z.Y. Qian, Basic Clin. Pharmacol. Toxicol. 100, 31 (2007).
6. W.Y. Gao and D.Y. Zhu, Chin. Tradit. Herb. Drugs 30, 389 (1999).
7. T.Z. Liu, Y. Lu, C.Y. Bao, and Z.Y. Qian, J. China Pharm. Univ. 33, 505 (2002).
8. W.P. Yu, Z.Y. Qian, G.L. Xu, and C.X. Shen, Chin. Tradit. Herb. Drugs 35, 68 (2004).
9. X.C. Shen and Z.Y. Qian, Acta Pharm. Sin. 39, 172 (2004).
10. X.C. Shen and Z.Y. Qian, Pharmazie 61, 348 (2006).
11. J.K. Amin, L. Xiao, D.R. Pimental, P.K. Pagano, K. Singh, D.B. Sawyer, and W. Colucci, J. Mol. Cell. Cardiol. 33, 131 (2001).
12. G.M. Kuster, D.R. Pimentel, T. Adachi, Y. Ido, D.A. Brenner, R.A. Cohen, R. Liao, D.A. Siwik, and W.S. Colucci, Circulation 111, 1192 (2005).
13. F. Qin, N.K. Rounds, W. Mao, K. Kawai, and C.S. Liang, Cardiovasc. Res. 51, 736 (2001).
14. M.K. Gupta, T.V. Neelakantan, M. Sanghamitra, R.K. Tyaqi, A. Dinda, S. Maulik, C.K. Mukhopadhyay, and S.K. Goswami, Antioxid. Redox. Signal. 8, 1081 (2006).
15. M. Neri, D. Cerretani, A.I. Fiaschi, P.F. Laghi, P.E. Lazzerini, A.B. Maffione, L. Micheli, G. Bruni, C. Nencini, G. Giorgi, S. D'Errico, C. Fiore, C. Pomara, I. Riezzo, E. Turillazzi, and V. Fineschi, J. Cell. Mol. Med. 11, 156 (2007).
16. S. Roychowdhury, G. Wolf, G. Keilhoff, and T.F. Horn, Nitric Oxide 8, 39 (2003).
17. J.D. Port and M.R. Bristow, J. Mol. Cell. Cardiol. 33, 887 (2001).
18. J. Sadoshima and S. Izumo, Circ. Res. 73, 413 (1993).
19. S. Yang, H. Zhu, Y. Li, H. Lin, G. Gabrielson, M.A. Trush, and A.M. Diehl, Arch. Biochem. Biophys. 378, 259 (2000).
20. J.J. Sedmark and S.E. Grossberg, Anal. Biochem. 79, 544 (1977).
21. B.S. Kristal, J. Chen, and B.P. Yu, Free Radic. Biol. Med. 16, 323 (1994).
22. D.B. Sawyer, R. Fukazawa, M.A. Arstall, and R.A. Kelly, Circ. Res. 84, 257 (1999).
23. H. Hong and G.Q. Liu, Life Sci. 74, 2959 (2004).
24. T. Satoh, Y. Enokido, H. Aoshima, Y. Uchiyama, and H. Hatanaka, J. Neurosci. Res. 50, 413 (1997).
25. W.B. Luo and Y.P. Wang, Acta Pharm. Sin. 22, 1135 (2001).