Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats

Fundamental and Clinical Pharmacology

Volumn 23, Issue 3, 2009, Pages 311-321

  Einbond, Linda Saxe ^a   Soffritti, Morando ^b   Esposti, Davide Degli ^b   Park, Taesik ^a   Cruz, Erica ^a   Su, Tao ^a   Wu, Hsan Au ^a   Wang, Xiaomei ^a   Zhang, Yu Jing ^a   Ham, Justin ^a   Goldberg, Ira J ^a   Kronenberg, Fredi ^a   Vladimirova, Antoaneta ^c  

^a Department of Neurology and the Taub Institute for Research on Alzheimer's Disease and the Aging Brain   (United States)

^b European Ramazzini Foundation of Oncology and Environmental Sciences   (Italy)

^c Iconix/Entelos Biosciences   (United States)

Author keywords

Actein; black cohosh; microarray; statin; triterpene glycoside

Indexed keywords

ACTEIN; ANTILIPEMIC AGENT; ANTINEOPLASTIC AGENT; CALGRANULIN B; CHOLESTEROL; CYTOCHROME P450; FATTY ACID; HYDROXYMETHYLGLUTARYL COENZYME A SYNTHASE; INHIBITOR OF DIFFERENTIATION 3; PROTEIN P53; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD SAMPLING; CANCER CELL; CANCER INHIBITION; CHOLESTEROL LIVER LEVEL; CIMICIFUGA RACEMOSA; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; FEMALE; GENE; GENE ACTIVATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE INDUCTION; GENOME ANALYSIS; HUMAN; HUMAN CELL; LIPID LIVER LEVEL; LIVER; LIVER CANCER; LIVER CARCINOGENESIS; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; STRESS; TREATMENT DURATION;

ANIMALS; BIOLOGICAL AVAILABILITY; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHOLESTEROL; CIMICIFUGA; FATTY ACIDS, NONESTERIFIED; FEMALE; GENE EXPRESSION REGULATION; HUMANS; LIVER; LIVER NEOPLASMS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SAPONINS; TIME FACTORS; TRITERPENES;

EID: 67149120806     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2009.00673.x     Document Type: Article

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