Inhibition of Src activity decreases tyrosine phosphorylation of occludin in brain capillaries and attenuates increase in permeability of the blood-brain barrier after transient focal cerebral ischemia

Journal of Cerebral Blood Flow and Metabolism

Volumn 29, Issue 6, 2009, Pages 1099-1108

  Takenaga, Yuji ^a   Takagi, Norio ^a   Murotomi, Kazutoshi ^a   Tanonaka, Kouichi ^a   Takeo, Satoshi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Blood?brain barrier; Brain capillaries; Ischemia; Occluding; Tyrosine phosphorylation

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; OCCLUDIN; PROTEIN TYROSINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL PERMEABILITY; BRAIN CAPILLARY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CAPILLARIES; ISCHEMIC ATTACK, TRANSIENT; MALE; MEMBRANE PROTEINS; PHOSPHOTYROSINE; PROTEIN KINASE INHIBITORS; PYRIMIDINES; RATS; RATS, SPRAGUE-DAWLEY; SRC-FAMILY KINASES; TIGHT JUNCTIONS; TIME FACTORS;

EID: 67149108182     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2009.30     Document Type: Article

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