-
1
-
-
31144433061
-
Cyclic nucleotide phosphodiesterase superfamily: A new target for the development of specific therapeutic agents
-
Lugnier R. Cyclic nucleotide phosphodiesterase superfamily: a new target for the development of specific therapeutic agents. Pharmacol Ther 2006; 109:366-398.
-
(2006)
Pharmacol Ther
, vol.109
, pp. 366-398
-
-
Lugnier, R.1
-
2
-
-
0034904647
-
Cilostazol represses vascular cell adhesion molecule-1 gene transcription via inhibiting NF-κB binding to its recognition sequence
-
Otsuki M, Saito H, Xu X, Sumitani S, Kouhara H, Kurabayashi M, et al. Cilostazol represses vascular cell adhesion molecule-1 gene transcription via inhibiting NF-κB binding to its recognition sequence. Atherosclerosis 2001; 158:121-128.
-
(2001)
Atherosclerosis
, vol.158
, pp. 121-128
-
-
Otsuki, M.1
Saito, H.2
Xu, X.3
Sumitani, S.4
Kouhara, H.5
Kurabayashi, M.6
-
3
-
-
0036156874
-
Inhibition of lipopolysaccharide- induced apoptosis by cilostazol in human umbilical vein endothelial cells
-
Kim KY, Shin HK, Choi JM, Hong KW. Inhibition of lipopolysaccharide- induced apoptosis by cilostazol in human umbilical vein endothelial cells. J Pharmacol Exp Ther 2002; 300:709-715.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 709-715
-
-
Kim, K.Y.1
Shin, H.K.2
Choi, J.M.3
Hong, K.W.4
-
4
-
-
9844267305
-
Cilostazol, a cAMP phosphodiesterase inhibitor, attenuates the production of monocyte chemoattractant protein-1 in response to tumor necrosis factor-α in vascular endothelial cells
-
Nishio Y, Kashiwagi N,Takahara N, Hidaka H, Kikkawa R. Cilostazol, a cAMP phosphodiesterase inhibitor, attenuates the production of monocyte chemoattractant protein-1 in response to tumor necrosis factor-α in vascular endothelial cells. Hrm Metab Res 1997; 29:491-495.
-
(1997)
Hrm Metab Res
, vol.29
, pp. 491-495
-
-
Nishio, Y.1
Kashiwagi, N.2
Takahara, N.3
Hidaka, H.4
Kikkawa, R.5
-
5
-
-
0343815764
-
Inhibitory effects of phosphodiesterase inhibitors on experimental autoimmune encephalomyelitis
-
Tamaru T, Suzumura A, Takayanagi T. Inhibitory effects of phosphodiesterase inhibitors on experimental autoimmune encephalomyelitis. Neuroimmunology 1998; 6:154-155.
-
(1998)
Neuroimmunology
, vol.6
, pp. 154-155
-
-
Tamaru, T.1
Suzumura, A.2
Takayanagi, T.3
-
6
-
-
0033103620
-
-
Fujimoto T, Sakoda S, Fujimura H, Yanagihara T. Ibudilast, a phospho- diesterase inhibitor, ameliorates experimental autoimmune encephalomyelitis in Dark August rats. J Neuroimmunol 1999; 95:35-42.
-
Fujimoto T, Sakoda S, Fujimura H, Yanagihara T. Ibudilast, a phospho- diesterase inhibitor, ameliorates experimental autoimmune encephalomyelitis in Dark August rats. J Neuroimmunol 1999; 95:35-42.
-
-
-
-
7
-
-
0034255695
-
et al.The type IV phosphodiesterase specific inhibitor mesopram inhibits experimental autoimmune encephalomyelitis in rodents
-
Dinter H, Tse J, Halks-Miller M, Asarnow D, Onuffer J, Faulds D, et al.The type IV phosphodiesterase specific inhibitor mesopram inhibits experimental autoimmune encephalomyelitis in rodents. J Neuroimmunol 2000; 108:136-146.
-
(2000)
J Neuroimmunol
, vol.108
, pp. 136-146
-
-
Dinter, H.1
Tse, J.2
Halks-Miller, M.3
Asarnow, D.4
Onuffer, J.5
Faulds, D.6
-
8
-
-
0345517245
-
Type IV phosphodiesterase inhibition in experimental allergic encephalomyelitis of Lewis rats: Sequential gene expression analysis of cytokines, adhesion molecules and the inducible nitric oxide synthase
-
Martine I, Puerta C, Redondo C, Garcia-Merino A. Type IV phosphodiesterase inhibition in experimental allergic encephalomyelitis of Lewis rats: sequential gene expression analysis of cytokines, adhesion molecules and the inducible nitric oxide synthase. J Neurol Sci 1999; 164:13-23.
-
(1999)
J Neurol Sci
, vol.164
, pp. 13-23
-
-
Martine, I.1
Puerta, C.2
Redondo, C.3
Garcia-Merino, A.4
-
9
-
-
33749028750
-
-
Moore CS, Earl N, Frenette R, Styhler A, Mancini JA, Nicholson DW, et al. Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bisdifluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2- hydroxypropan-2-yl)- phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis. J Pharmacol Exp Ther 2006; 319:63-72.
-
Moore CS, Earl N, Frenette R, Styhler A, Mancini JA, Nicholson DW, et al. Peripheral phosphodiesterase 4 inhibition produced by 4-[2-(3,4-Bisdifluoromethoxyphenyl)-2-[4-(1,1,1,3,3,3-hexafluoro-2- hydroxypropan-2-yl)- phenyl]-ethyl]-3-methylpyridine-1-oxide (L-826,141) prevents experimental autoimmune encephalomyelitis. J Pharmacol Exp Ther 2006; 319:63-72.
-
-
-
-
10
-
-
33747894116
-
Selective COX-2 inhibitor celecoxib prevents experimental autoimmune encephalomyelitis through COX-2-independent pathway
-
Miyamoto K, Miyake S, Mizuno M, Oka N, Kusunoki S, Yamamura T. Selective COX-2 inhibitor celecoxib prevents experimental autoimmune encephalomyelitis through COX-2-independent pathway. Brain 2006; 129:1984-1992.
-
(2006)
Brain
, vol.129
, pp. 1984-1992
-
-
Miyamoto, K.1
Miyake, S.2
Mizuno, M.3
Oka, N.4
Kusunoki, S.5
Yamamura, T.6
-
11
-
-
3342988190
-
-
Claveau D, Chen SL, O'Keefe S, Zaller DM, Styhler A, Liu S, et al. Preferential inhibition of T helper 1, but not T helper 2, cytokines in vitro by L-826,141 [4-2-(3,4-Bisdifluromethoxyphenyl)-2-4-(1,1,1,3,3, 3-hexafluoro-2-hydroxypropan-2-yl)-phenyl-ethyl-3-methylpyridine-1-oxide], a potent and selective phosphodiesterase 4 inhibitor. J Pharmacol Exp Ther 2004; 310:752-760.
-
Claveau D, Chen SL, O'Keefe S, Zaller DM, Styhler A, Liu S, et al. Preferential inhibition of T helper 1, but not T helper 2, cytokines in vitro by L-826,141 [4-2-(3,4-Bisdifluromethoxyphenyl)-2-4-(1,1,1,3,3, 3-hexafluoro-2-hydroxypropan-2-yl)-phenyl-ethyl-3-methylpyridine-1-oxide], a potent and selective phosphodiesterase 4 inhibitor. J Pharmacol Exp Ther 2004; 310:752-760.
-
-
-
-
12
-
-
0033532995
-
Ibudilast suppresses TNFα production by Glias cells functioning mainly as type III phosphodiesterase inhibitor in the CNS
-
Suzumura A, Ito A, Yoshikawa M, Sawada M. Ibudilast suppresses TNFα production by Glias cells functioning mainly as type III phosphodiesterase inhibitor in the CNS. Brain Res 1999; 837:203-212.
-
(1999)
Brain Res
, vol.837
, pp. 203-212
-
-
Suzumura, A.1
Ito, A.2
Yoshikawa, M.3
Sawada, M.4
-
13
-
-
0345392549
-
Phosphodiesterase inhibitors suppress IL-12 production with Microglia and T helper 1 development
-
Suzumura A, Ito A, Mizuno T. Phosphodiesterase inhibitors suppress IL-12 production with Microglia and T helper 1 development. Mult Scler 2003; 9:574-578.
-
(2003)
Mult Scler
, vol.9
, pp. 574-578
-
-
Suzumura, A.1
Ito, A.2
Mizuno, T.3
-
14
-
-
0034650812
-
Therapeutic potential of phosphodiesterase-4 and -3 inhibitors in Th1-mediated autoimmune diseases
-
Bielekova B, Lincoln A, Mcfarland H, Martin R. Therapeutic potential of phosphodiesterase-4 and -3 inhibitors in Th1-mediated autoimmune diseases. J Immunol 2000; 164:1117-1124.
-
(2000)
J Immunol
, vol.164
, pp. 1117-1124
-
-
Bielekova, B.1
Lincoln, A.2
Mcfarland, H.3
Martin, R.4
-
15
-
-
0032918227
-
Effects of phosphodiesterase inhibitors on cytokine production by microglia
-
Yoshikawa M, Suzumura A, Tamaru T, Takayanagi T, Sawada M. Effects of phosphodiesterase inhibitors on cytokine production by microglia. Mul Scler 1999; 5:126-133.
-
(1999)
Mul Scler
, vol.5
, pp. 126-133
-
-
Yoshikawa, M.1
Suzumura, A.2
Tamaru, T.3
Takayanagi, T.4
Sawada, M.5
-
16
-
-
33846253253
-
Intercellular adhesion molecule-1 expression is required on multiple cell type for the development of experimental autoimmune encephalomyelitis
-
Bullard DC, Hu X, Schoeb TR, Collins RG, Beardet AL, Barnum SR. Intercellular adhesion molecule-1 expression is required on multiple cell type for the development of experimental autoimmune encephalomyelitis. J Immunol 2007; 178:851-857.
-
(2007)
J Immunol
, vol.178
, pp. 851-857
-
-
Bullard, D.C.1
Hu, X.2
Schoeb, T.R.3
Collins, R.G.4
Beardet, A.L.5
Barnum, S.R.6
-
17
-
-
0027241616
-
Expression of endothelial cell activation antigens in microvessels from patients with multiple sclerosis
-
Dore-Duffy P, Washington R, Dragovic L. Expression of endothelial cell activation antigens in microvessels from patients with multiple sclerosis. Adv Exp Med Biol 1993; 331:243-248.
-
(1993)
Adv Exp Med Biol
, vol.331
, pp. 243-248
-
-
Dore-Duffy, P.1
Washington, R.2
Dragovic, L.3
-
18
-
-
0027409052
-
Increased levels of circulating ICAM-1 in serum and cerebrospinal fluid of patients with active multiple sclerosis. Correlation with TNF-alpha and blood-brain barrier damage
-
Sharief MK, Noori MA, Ciardi M, Cirelli A, Thompson EJ. Increased levels of circulating ICAM-1 in serum and cerebrospinal fluid of patients with active multiple sclerosis. Correlation with TNF-alpha and blood-brain barrier damage. J Neuroimmunol 1993; 43:15-21.
-
(1993)
J Neuroimmunol
, vol.43
, pp. 15-21
-
-
Sharief, M.K.1
Noori, M.A.2
Ciardi, M.3
Cirelli, A.4
Thompson, E.J.5
-
19
-
-
0027361834
-
Soluble intercellular adhesion molecule-1 in cerebrospinal fluid: An indicator for the inflammatory impairment of the blood-cerebrospinal fluid barrier
-
Rieckmann P, Nunke K, Burchhardt M, Albrecht M, Wiltfang J, Ulrich M, et al. Soluble intercellular adhesion molecule-1 in cerebrospinal fluid: an indicator for the inflammatory impairment of the blood-cerebrospinal fluid barrier. J Neuroimmunol 1993; 47:133-140.
-
(1993)
J Neuroimmunol
, vol.47
, pp. 133-140
-
-
Rieckmann, P.1
Nunke, K.2
Burchhardt, M.3
Albrecht, M.4
Wiltfang, J.5
Ulrich, M.6
-
20
-
-
0031726268
-
Effect of cilostazol on soluble adhesion molecules and platelet-derived microparticles in patients with diabetes
-
Nomura S, Shouzu A, Omoto S, Hayakawa T, Kagawa H, Nishikawa M, et al. Effect of cilostazol on soluble adhesion molecules and platelet-derived microparticles in patients with diabetes. Thromb Haemost 1998; 80:388-392.
-
(1998)
Thromb Haemost
, vol.80
, pp. 388-392
-
-
Nomura, S.1
Shouzu, A.2
Omoto, S.3
Hayakawa, T.4
Kagawa, H.5
Nishikawa, M.6
-
21
-
-
4143075782
-
Cilostazol inhibits high glucose-mediated endothelial-neutrophil adhesion by decreasing adhesion molecule expression via NO production
-
Omi H, Okayama N, Shimizu M, Fukutomi T, Nakamura A, Imaeda K, et al. Cilostazol inhibits high glucose-mediated endothelial-neutrophil adhesion by decreasing adhesion molecule expression via NO production. Microvasc Res 2004; 68:119-125.
-
(2004)
Microvasc Res
, vol.68
, pp. 119-125
-
-
Omi, H.1
Okayama, N.2
Shimizu, M.3
Fukutomi, T.4
Nakamura, A.5
Imaeda, K.6
|