Eosinophilic Inclusions in Rat Clara Cells and the Effect of an Inhaled Corticosteroid

Toxicologic Pathology

Volumn 37, Issue 3, 2009, Pages 315-323

  Kambara, Takahito ^a,b   Mckevitt, Tom P ^a   Francis, Ian ^a   Woodfine, Jennie A ^a   Mccawley, Sean J ^a   Jones, Stewart A ^c   Pilling, Andrew M ^c   Lewis, David J ^a   Williams, Tom C ^a  

^a GLAXOSMITHKLINE   (United States)

^b Safety   (United States)

^c HUNTINGDON LIFE SCIENCES   (United Kingdom)

Author keywords

CCSP; Clara cell; corticosteroid; eosinophilic inclusion; inhalation; rat; SP D

Indexed keywords

CELL PROTEIN; CLARA CELL PROTEIN; CORTICOSTEROID; MESSENGER RNA; SURFACTANT PROTEIN D; CLARA CELL SPECIFIC PROTEIN; CLARA CELL-SPECIFIC PROTEIN; UTEROGLOBIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CELL GRANULE; CELL INCLUSION; CLARA CELL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG EFFECT; DRUG MEGADOSE; ELECTRON MICROSCOPY; EOSINOPHIL COUNT; EOSINOPHILIC CYTOPLASMIC INCLUSION; EXPOSURE; FEMALE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LOW DRUG DOSE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; DOSE RESPONSE; EOSINOPHIL; EPITHELIUM CELL; GENETICS; INHALATIONAL DRUG ADMINISTRATION; METABOLISM; ULTRASTRUCTURE; WISTAR RAT;

RATTUS;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EOSINOPHILS; EPITHELIAL CELLS; FEMALE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INCLUSION BODIES; INHALATION EXPOSURE; MALE; PULMONARY SURFACTANT-ASSOCIATED PROTEIN D; RATS; RATS, WISTAR; RNA, MESSENGER; UTEROGLOBIN;

EID: 67049107893     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/0192623309332989     Document Type: Article

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