Prevention of death in bacterium-infected mice by a synthetic antimicrobial peptide, L5, through activation of host immunity

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 6, 2009, Pages 2510-2516

  Okuyama Nishida, Yukiko ^a   Akiyama, Nobuko ^a   Sugimori, Giichi ^b   Nomura, Kazuhide ^b   Ogawa, Kenji ^a   Homma, Koichi J ^c   Sekimizu, Kazuhisa ^d   Tsujimoto, Masafumi ^a   Natori, Shunji ^a  

^a RIKEN   (Japan)

^b SHIONOGI AND CO LTD   (Japan)

^c TEIKYO UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL PEPTIDE L3; ANTIMICROBIAL PEPTIDE L5; CXCL1 CHEMOKINE; CXCL11 CHEMOKINE; CXCL2 CHEMOKINE; EOTAXIN 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 8; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; POLYPEPTIDE ANTIBIOTIC AGENT; RANTES; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; SYNTHETIC PEPTIDE; THIOGLYCOLIC ACID; THYMUS AND ACTIVATION REGULATED CHEMOKINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC PROPHYLAXIS; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; CXCL9 GENE; DEATH; DRUG EFFICACY; DRUG MECHANISM; ENTEROCOCCUS FAECALIS; ESCHERICHIA COLI; FEMALE; GENE; GENE EXPRESSION REGULATION; HOST; IMMUNE RESPONSE; IN VIVO STUDY; INFLAMMATION; INNATE IMMUNITY; INOCULATION; LEUKOCYTE ACTIVATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; UPREGULATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; CHEMOKINE CXCL9; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; INJECTIONS, INTRAPERITONEAL; MACROPHAGE ACTIVATION; MICE; MICE, INBRED ICR; NEUTROPHIL ACTIVATION; OLIGOPEPTIDES; REACTIVE OXYGEN SPECIES; STEREOISOMERISM;

EID: 67049086916     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00863-08     Document Type: Article

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