Synthesis and evaluation of two uncharged 99mTc-labeled derivatives of thioflavin-T as potential tracer agents for fibrillar brain amyloid

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 52, Issue 6, 2009, Pages 227-235

  Serdons, K ^a   Vanderghinste, D ^b   Van Eeckhoudt, M ^a   Cleynhens, J ^a   De Groot, T ^b   Bormans, G ^a   Verbruggen, A ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

2 phenylbenzothiazoles; Amyloid; SPECT; Technetium 99m; Thioflavin T

Indexed keywords

BLOOD; GLYCOPROTEINS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NEURODEGENERATIVE DISEASES;

2-PHENYLBENZOTHIAZOLE; AMYLOID; BRAIN UPTAKE; FLUORESCENT DYES; IN-VITRO; LABELINGS; SPECT; SYNTHESISED; TECHNETIUM-99M; THIOFLAVIN T;

ELECTROPHORESIS;

2 (2' HYDROXY 4' AMINOPHENYL) 1,3 BENZOTHIAZOLE; 2 (4' AMINOPHENYL) 6 (3'' 4 TOSYLOXYPROPOXY) 1,3 BENZOTHIAZOLE; 2 (4' AMINOPHENYL) 6 HYDROXY 1,3 BENZOTHIAZOLE; 2 (4' AMINOPHENYL) 6 METHOXY 1,3 BENZOTHIAZOLE; 2 (4' NITROPHENYL) 6 METHOXY 1,3 BENZOTHIAZOLE; 2 [2' (3'' 4 TOSYLOXYPROPOXY) 4' AMINO] 1,3 BENZOTHIAZOLE; AMYLOID; BENZOTHIAZOLE DERIVATIVE; N 4' METHOXY 4 NITROTHIOBENZAMIDE; N 4' METHOXYPHENYL 4 NITROBENZAMIDE; TECHNETIUM 99M; THIOFLAVINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; ELECTROPHORESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; MASS SPECTROMETRY; MOUSE; NEUROIMAGING; NONHUMAN; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

MUS;

EID: 66949116780     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1592     Document Type: Article

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