TRAIL-induced cleavage and inactivation of SPAK sensitizes cells to apoptosis

Biochemical and Biophysical Research Communications

Volumn 349, Issue 3, 2006, Pages 1016-1024

  Polek, Tara C ^a   Talpaz, Moshe ^a   Spivak Kroizman, Taly R ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Apoptosis; Caspases; Kinases; Signal transduction; SPAK; Ste20; TRAIL

Indexed keywords

CASPASE; ENZYME; PROTEINASE; SMALL INTERFERING RNA; STE20 RELATED PROLINE ALANINE RICH KINASE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME SUBSTRATE COMPLEX; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; ASPARTIC ACID; BINDING SITES; CASPASES; DOWN-REGULATION; ENZYME ACTIVATION; HELA CELLS; HUMANS; MEMBRANE GLYCOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SUBSTRATE SPECIFICITY; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33748634924     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.08.118     Document Type: Article

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