An essential role for ClC-4 in transferrin receptor function revealed in studies of fibroblasts derived from Clcn4-null mice

Journal of Cell Science

Volumn 122, Issue 8, 2009, Pages 1229-1235

  Mohammad Panah, Raha ^a   Wellhauser, Leigh ^a,b   Steinberg, Benjamin E ^a   Wang, Yanchun ^a   Huan, Ling Jun ^a   Liu, Xiang Dong ^a   Bear, Christine E ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

ClC family; Endosomal pH; Primary fibroblast cell line

Indexed keywords

CHLORIDE CHANNEL; CHLORIDE CHANNEL 3; CHLORIDE CHANNEL 4; CHLORIDE CHANNEL 5; DESOXIFERRAMINE; EPIDERMAL GROWTH FACTOR RECEPTOR; IRON CHELATING AGENT; MESSENGER RNA; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG; CLC 3 CHANNEL; CLC 5 CHLORIDE CHANNEL; CLC-3 CHANNEL; CLC-5 CHLORIDE CHANNEL; CLCN4 1 PROTEIN, MOUSE; CLCN4-1 PROTEIN, MOUSE; TRANSFERRIN;

ACIDIFICATION; ALKALINITY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PH; CELL SURFACE; CONTROLLED STUDY; DISSOCIATION; ENDOCYTOSIS; ENDOSOME; FIBROBLAST; IRON TRANSPORT; LIGAND BINDING; LYSOSOME; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; WILD TYPE; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOUSE MUTANT; PH; PROTEIN TRANSPORT; TIME;

MUS;

ANIMALS; CELLS, CULTURED; CHLORIDE CHANNELS; ENDOCYTOSIS; ENDOSOMES; FIBROBLASTS; HYDROGEN-ION CONCENTRATION; IRON CHELATING AGENTS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEIN TRANSPORT; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, TRANSFERRIN; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; TRANSFERRIN;

EID: 66849121673     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.037317     Document Type: Article

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