Simultaneous lack of catalase and beta-toxin in Staphylococcus aureus leads to increased intracellular survival in macrophages and epithelial cells and to attenuated virulence in murine and ovine models

Microbiology

Volumn 155, Issue 5, 2009, Pages 1505-1515

  Martínez Pulgarín, Susana ^a,b   Domínguez Bernal, Gustavo ^a   Orden, José A ^a   de la Fuente, Ricardo ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b INIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TOXIN; CATALASE; STAPHYLOCOCCUS TOXIN; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIAL TOXIN; HEMOLYSIN; HLB PROTEIN, STAPHYLOCOCCUS AUREUS; SPHINGOMYELIN PHOSPHODIESTERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE SEVERITY; EPITHELIUM CELL; FEMALE; GENE DELETION; LD 50; MACROPHAGE; MICROBIAL ATTENUATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHEEP; STAPHYLOCOCCUS AUREUS; ANIMAL; BAGG ALBINO MOUSE; CATTLE; CELL LINE; DISEASE MODEL; GENETICS; HUMAN; METABOLISM; MICROBIOLOGY; MUTATION; PATHOGENICITY; PHYSIOLOGY; STAPHYLOCOCCUS INFECTION; VIRULENCE;

ANIMALIA; BACTERIA (MICROORGANISMS); BOVINAE; MURINAE; MUS; OVIS; OVIS ARIES; STAPHYLOCOCCUS AUREUS;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; CATALASE; CATTLE; CELL LINE; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FEMALE; HEMOLYSIN PROTEINS; HUMANS; MACROPHAGES; MICE; MICE, INBRED BALB C; MUTATION; SHEEP; SPHINGOMYELIN PHOSPHODIESTERASE; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; VIRULENCE;

EID: 66849087184     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.025544-0     Document Type: Article

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