Effect of staphylococcal β toxin on the cytotoxicity, proliferation and adherence of Staphylococcus aureus to bovine mammary epithelial cells

Veterinary Microbiology

Volumn 48, Issue 3-4, 1996, Pages 187-198

  Cifrian, E ^a,b   Guidry, A J ^b   Bramley, A J ^c   Norcross, N L ^d   Bastida Corcuera, F D ^d   Marquardt, W W ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b AGRICULTURAL RESEARCH SERVICE   (United States)

^c UNIVERSITY OF VERMONT   (United States)

^d Department of Obstetrics Gynecology   (United States)

Author keywords

Bacterial adherence; Cytotoxicity; Epithelial cells; Mammary gland; Staphylococcus aureus; Toxin

Indexed keywords

STAPHYLOCOCCUS TOXIN;

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIUM ADHERENCE; CONTROLLED STUDY; CYTOTOXICITY; EPITHELIUM CELL; IN VITRO STUDY; MAMMARY GLAND; NONHUMAN; STAPHYLOCOCCUS AUREUS;

EID: 0030000594     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1135(95)00159-X     Document Type: Article

References (35)

1. Anderson, J.C., 1977. Experimental staphylococcal mastitis in the mouse: The induction of chronic mastitis and its response to antibiotic therapy. J. Comp. Pathol., 87: 611-621.
2. Bhakdi, S. and Tranum-Jensen, J., 1987. Damage to mammalian cells by proteins that form transmembrane pores. Rev. Physiol. Biochem. Pharmacol., 107: 147-208.
3. Bhakdi, S. and Tranum-Jensen, J., 1991. Alpha-toxin of Staphylococcus aureus. Microbiol. Rev., 55: 733-751.
4. Bramley, A.J., Patel, A.H., O'Reilly, M., Foster, R. and Foster, T.J., 1989. Roles of α-toxin and β-toxin in virulence of Staphylococcus aureus for the mouse mammary gland. Infect. Immun., 57: 2489-2494.
5. Calvinho, L.F., Donnelly, W.J. and Dodd, K., 1993. Effect of partially purified Staphylococcus aureus beta-haemolysin on the mammary gland of the mouse. J. Vet. Med., B40: 559-568.
6. Capuco, A.V., Paape, M.J., Smith, J.J. and Loeffler, D.A., 1985. In vitro effect of bacterial toxins on lactating bovine mammary tissue. J. Dairy Sci., 68(Suppl 1):206.
7. Cifrian, E., Guidry, A.J., O'Brian, C.N., Nickerson, S.C. and Marquardt, W.W., 1994. Adherence of Staphylococcus aureus to cultured bovine mammary epithelial cells. J. Dairy Sci., 77: 970-983.
8. Cifrian, E., Guidry, A.J., O'Brian, C.N. and Marquardt, W.W., 1995. Effect of alpha-toxin and capsular exopolysaccharide on the adherence of Staphylococcus aureus to cultured teat, ductal and secretory mammary epithelial cells. Res. Vet. Sci., 58: 20-25.
9. Darnell, J., Lodish, H. and Baltimore, D., 1990. Transport across cell membranes. In: Molecular Cell Biology, Scientific American Books, NY, pp.531-582.
10. Foster, T.J., O'Reilly, M., Patel, A.H. and Bramley, J., 1988a. Genetic studies of Staphylococcus aureus virulence factors. Antonie van Leeuwenhoek, 54: 475-482.
11. Foster, T.J., O'Reilly, M., Patel, A.H., Nowlan P. and Bramley, J., 1988b. Genetic analysis of the role of toxins and protein A in the pathogenesis of Staphylococcus aureus infections. Properties of an unexpressed α-toxin locus from a clinical isolate. In: Bacterial Protein Toxins, Fehrenbach et al. (editors), Fischer, G., NY, Zbl. Bakt. (Suppl. 17):343-349.
12. Freer, J.H. and Arbuthnott, J.P., 1983. Toxins of Staphylococcus aureus. Pharmac. Ther., 19: 55-106.
13. Freshney, R.I., 1987. Characterization. In: Culture of Animal Cells. A Manual of Basic Technique, Alan R. Liss Inc., NY, pp.169-185.
14. Frost, A.J., 1975. Selective adhesion of microorganisms to the ductular epithelium of the bovine mammary gland. Infect. Immun., 12: 1154-1156.
15. Haraldsson, I. and Jonsson, P., 1984. Histopathology and pathogenesis of mouse mastitis induced with Staphylococcus aureus mutants. J. Comp. Path., 94:183-196.
16. Haugland, R.P., 1992. Fluorescent dyes for assessing vital cell functions. In: Molecular Probes, Handbook of Fluorescent Probes and Research Chemicals, Molecular Probes Inc., Eugene, OR, pp. 172-180.
17. Jasper, D.E. and Jain, N.C., 1966. Hemolytic behavior of staphylococci isolated from cow's milk. Can. J. Comp. Med. Vet. Sci., 30: 63-70.
18. Jasper, D.E., MacDonald, J.S., Mochrie, R.D., Philpato, W.A., Farnsworth, R.J. and Spender, S.B., 1982. Bovine mastitis research: Needs, funding, and sources of support. In: Proceedings of the 21st Annual Meeting of the National Mastitis Council, National Mastitis Council, Louisville, KY, pp. 184-193.
19. Jonsson, P., Lindberg, M., Haraldsson, I. and Wadstrom, T., 1985. Virulence of Staphylococcus aureus in a mouse mastitis model: studies of alpha-haemolysin, coagulase and protein A as possible virulence determinants with protoplast fusion and gene cloning. Infect. Immun., 49: 765-769.
20. Jonsson, P. and Wadstrom, T., 1993. Staphylococcus. In: Pathogenesis of Bacterial Infections in Animals, Iowa State University Press, Ames, pp. 21-35.
21. Kinsman, O., Jonsson, P., Haraldsson, I., Lindberg, J., Arbuthnott, J.P. and Wadstrom, T., 1981. Decreased virulence of alpha-haemolysin-negative and coagulase-negative mutants of Staphylococcus aureus in experimental infections in mice. In: Staphylococci and Staphylococcal Infections, Jeljaszewicz, J. (editor), Gustav Fischer Verlag, Stuttgart-New York, pp. 651-659.
22. Low, D.K.R. and Freer, J.H., 1977. Biological effects of highly purified β-lysin (sphingomyelinase C) from Staphylococcus aureus. FEMS Letts., 2: 133-138.
23. Matsunaga, T., Kamata, S., Kakiichi, N. and Uchida, K., 1993. Characteristics of Staphylococcus aureus isolated from peracute, acute and chronic bovine mastitis. J. Vet. Med. Sci., 55: 297-300.
24. Mollby, R., 1976. Effect of staphylococcal β-haemolysin (sphingomyelinase C) on cell membranes. In: Staphylococci and Staphylococcal Infections, Jeljaszewicz, J. (editor), Gustav Fischer Verlag, Stuttgart-New York, pp. 665-677.
25. Mollby, R. and Thelestam, M., 1981. Bacterial phospholipases with special reference to staphylococcal beta-haemolysin. In: Staphylococci and Staphylococcal Infections, Jeljaszewicz, J. (editor), Gustav Fischer Verlag, Stuttgart-New York, pp. 243-252.
26. Reneau, J.K., 1993. Guidelines for clinical mastitis treatment and evaluation. In: Proceedings of the 1993 Regional Meeting of the National Mastitis Council, National Mastitis Council, Syracuse, NY, pp. 24-37.
27. Shapiro, H.M., 1988. Parameters and probes. In: Practical Flow Cytometry, Alan R. Liss Inc., NY, pp. 115-198.
28. Szmigielski, S., Jeljaszewicz, J., Kobus, M., Luczak, M., Ludwicka, A., Mollby, R. and Wadstrom, T., 1975. Cytotoxic effects of staphylococcal alpha-, beta-and gamma-hemolysins. In: Staphylococci and Staphylococcal Infections, Jeljaszewicz, J. (editor), Gustav Fischer Verlag, Stuttgart-New York, pp. 691-705.
29. Thelestam, M., 1983. Modes of membrane damaging action of staphylococcal toxins. In: Staphylococci and Staphylococcal Infections, Easmon, C.S.F., and Adlam, C. (editors), Academic Press, London, Vol.2: 705-744.
30. Thelestam, M., Mollby, R. and Wadstrom, T., 1973. Effects of staphylococcal alpha-, beta-, delta-and gamma-hemolysins on human diploid fibroblasts and HeLa cells: evaluation of a new quantitative assay for measuring cell damage. Infect. Immun., 8: 938-946.
31. Vann, J.M. and Proctor, R.A., 1988. Cytotoxic effects of ingested Staphylococcus aureus on bovine endothelial cells: Role of S. aureus α-hemolysin. Microb. Pathogen., 4: 443-453.
32. Ward, P.D., Adlam, C., McCartney, A.C., Arbuthnott, J.P. and Thorley, C.M., 1979. A histopathological study of the effects of highly purified staphylococcal alpha and beta toxins on the lactating mammary gland and skin of the rabbit. J. Comp. Pathol., 89: 169-177.
33. Wiseman, G.W., 1975. The hemolysins of Staphylococcus aureus. Bact. Rev., 39: 317-344.
34. Zavizion, B., Bramley, A.J., Politis, I. and Gilmore, J., 1994. Effects of Staphylococcus aureus toxins on proliferation of bovine mammary cells in vitro. J. Dairy Sci., 77(Suppl. 1):311.
35. Zavizion, B., Bramley, A.J., Politis, I. Gilmore, J., Turner, J.D., Patel, A.H. and Foster, T.J., 1995. Effects of Staphylococcus aureus toxins on the growth of bovine mammary epithelial cells (MAC-T) in culture. J. Dairy Sci., 78: 277-284.