Chronic nicotine blunts hypoxic sensitivity in perinatal rat adrenal chromaffin cells via upregulation of KATP channels: Role of α7 nicotinic acetylcholine receptor and hypoxia-inducible factor-2α

Journal of Neuroscience

Volumn 29, Issue 22, 2009, Pages 7137-7147

  Buttigieg, Josef ^a   Brown, Stephen ^a   Holloway, Alison C ^a   Nurse, Colin A ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BUNGAROTOXIN RECEPTOR; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; CATECHOLAMINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLIBENCLAMIDE; HYPOXIA INDUCIBLE FACTOR 2ALPHA; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; NICOTINE; PLACEBO; POTASSIUM; POTASSIUM CHANNEL; PROTEIN KINASE; PROTEIN KINASE C INHIBITOR; SHORT HAIRPIN RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CATECHOLAMINE RELEASE; CHROMAFFIN CELL; CONTROL GROUP; CONTROLLED STUDY; CYTOSOL; FEMALE; FETUS; HYPOXIA; IN VITRO STUDY; MEMBRANE DEPOLARIZATION; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; UPREGULATION;

ADRENAL GLANDS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CADMIUM; CALCIUM; CALCIUM CHANNEL BLOCKERS; CATECHOLAMINES; CELL HYPOXIA; CELLS, CULTURED; CHROMAFFIN CELLS; DRUG INTERACTIONS; ELECTROCHEMISTRY; ENZYME INHIBITORS; FEMALE; GLYBURIDE; MEMBRANE POTENTIALS; NICOTINE; NICOTINIC AGONISTS; PATCH-CLAMP TECHNIQUES; PEPTIDES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PREGNANCY; PROTEIN KINASE C; RATS; RATS, WISTAR; RECEPTORS, NICOTINIC; UP-REGULATION;

EID: 66749191478     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0544-09.2009     Document Type: Article

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