CD40 and OX40 ligand are differentially regulated on asthmatic airway smooth muscle

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 64, Issue 7, 2009, Pages 1074-1082

  Krimmer, D I ^b   Loseli, M ^b   Hughes, J M ^a   Oliver, B G G ^b,c   Moir, L M ^b,c   Hunt, N H ^a   Black, J L ^b,c   Burgess, J K ^a,b,c  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Discipline of Pharmacology   (Australia)

^c WOOLCOCK INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Adhesion molecules; Human airway smooth muscle cells; Interferon ; OX40 ligand; Tumour necrosis factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (2 AMINOETHYLAMINO) 1,8 DIMETHYLIMIDAZO[1,2 A]QUINOXALINE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CD40 ANTIGEN; CYCLOHEXIMIDE; CYTOKINE; HYBRID PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OX40 LIGAND; PROTEIN KINASE INHIBITOR; RECOMBINANT GAMMA INTERFERON; RECOMBINANT PROTEIN; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR RECEPTOR; UO 126;

AIRWAY; ANTIGEN EXPRESSION; ARTICLE; ASTHMA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOMODULATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; TRACHEA MUSCLE;

ADULT; AGED; ANTIGENS, CD40; ASTHMA; DRUG SYNERGISM; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INTERFERON-GAMMA; MAP KINASE KINASE 4; MIDDLE AGED; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; OX40 LIGAND; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 66749112939     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2009.01959.x     Document Type: Article

References (29)

1. Woodruff PG, Dolganov GM, Ferrando RE, Donnelly S, Hays SR, Solberg OD et al. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med 2004 169 : 1001 1006. (Pubitemid 38543637)
2. Lazaar AL, Albelda SM, Pilewski JM, Brennan B, Pure E, Panettieri RA Jr. T lymphocytes adhere to airway smooth muscle cells via integrins and CD44 and induce smooth muscle cell DNA synthesis. J Exp Med 1994 180 : 807 816. (Pubitemid 24256594)
3. Burgess JK, Blake AE, Boustany S, Johnson PR, Armour CL, Black JL et al. CD40 and OX40 ligand are increased on stimulated asthmatic airway smooth muscle. J Allergy Clin Immunol 2005 115 : 302 308. (Pubitemid 40215093)
4. Lazaar AL, Amrani Y, Hsu J, Panettieri RA Jr., Fanslow WC, Albelda SM et al. CD40-mediated signal transduction in human airway smooth muscle. J Immunol 1998 161 : 3120 3127. (Pubitemid 28425740)
5. Xu Y, Song G. The role of CD40-CD154 interaction in cell immunoregulation. J Biomed Sci 2004 11 : 426 438. (Pubitemid 38721026)
6. Fujita T, Ukyo N, Hori T, Uchiyama T. Functional characterization of OX40 expressed on human CD8+ T cells. Immunol Lett 2006 106 : 27 33. (Pubitemid 44093048)
7. Wang Q, Chen Y, Xie F, Ge Y, Chen L, Wu H et al. Development of a sandwich ELISA for evaluating soluble OX40L (CD252) in human sera of different ages or with Graves' disease. Cytokine 2006 36 : 23 28. (Pubitemid 46049016)
8. Ackerman V, Marini M, Vittori E, Bellini A, Vassali G, Mattoli S. Detection of cytokines and their cell sources in bronchial biopsy specimens from asthmatic patients. Relationship to atopic status, symptoms, and level of airway hyperresponsiveness. Chest 1994 105 : 687 696. (Pubitemid 24088441)
9. Cembrzynska-Nowak M, Szklarz E, Inglot AD, Teodorczyk-Injeyan JA. Elevated release of tumor necrosis factor-alpha and interferon-gamma by bronchoalveolar leukocytes from patients with bronchial asthma. Am Rev Respir Dis 1993 147 : 291 295. (Pubitemid 23044897)
10. Kumar RK, Herbert C, Webb DC, Li L, Foster PS. Effects of anticytokine therapy in a mouse model of chronic asthma. Am J Respir Crit Care Med 2004 170 : 1043 1048. (Pubitemid 39488615)
11. Tliba O, Panettieri RA Jr., Tliba S, Walseth TF, Amrani Y. Tumor necrosis factor-alpha differentially regulates the expression of proinflammatory genes in human airway smooth muscle cells by activation of interferon-beta-dependent CD38 pathway. Mol Pharmacol 2004 66 : 322 329. (Pubitemid 38989489)
12. Keslacy S, Tliba O, Baidouri H, Amrani Y. Inhibition of tumor necrosis factor-alpha-inducible inflammatory genes by interferon-gamma is associated with altered nuclear factor-kappaB transactivation and enhanced histone deacetylase activity. Mol Pharmacol 2007 71 : 609 618. (Pubitemid 46147925)
13. Amrani Y, Ammit AJ, Panettieri RA Jr. Tumor necrosis factor receptor (TNFR) 1, but not TNFR2, mediates tumor necrosis factor-alpha-induced interleukin-6 and RANTES in human airway smooth muscle cells: role of p38 and p42/44 mitogen-activated protein kinases. Mol Pharmacol 2001 60 : 646 655. (Pubitemid 32900245)
14. Amrani Y, Lazaar AL, Hoffman R, Amin K, Ousmer S, Panettieri RA Jr. Activation of p55 tumor necrosis factor-alpha receptor-1 coupled to tumor necrosis factor receptor-associated factor 2 stimulates intercellular adhesion molecule-1 expression by modulating a thapsigargin-sensitive pathway in human tracheal smooth muscle cells. Mol Pharmacol 2000 58 : 237 245. (Pubitemid 30452547)
15. Oltmanns U, Issa R, Sukkar MB, John M, Chung KF. Role of c-Jun N-terminal kinase in the induced release of GM-CSF, RANTES and IL-8 from human airway smooth muscle cells. Br J Pharmacol 2003 139 : 1228 1234. (Pubitemid 36920687)
16. Johnson PR, Roth M, Tamm M, Hughes M, Ge Q, King G et al. Airway smooth muscle cell proliferation is increased in asthma. Am J Respir Crit Care Med 2001 164 : 474 477. (Pubitemid 32778219)
17. Burgess JK, Carlin S, Pack RA, Arndt GM, Au WW, Johnson PR et al. Detection and characterization of OX40 ligand expression in human airway smooth muscle cells: a possible role in asthma? J Allergy Clin Immunol 2004 113 : 683 689. (Pubitemid 38530424)
18. Song J, So T, Cheng M, Tang X, Croft M. Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion. Immunity 2005 22 : 621 631. (Pubitemid 40719197)
19. Larche M, Robinson DS, Kay AB. The role of T lymphocytes in the pathogenesis of asthma. J Allergy Clin Immunol 2003 111 : 450 463. (Pubitemid 36337859)
20. Burgess JK, Johnson PR, Ge Q, Au WW, Poniris MH, McParland BE et al. Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. Am J Respir Crit Care Med 2003 167 : 71 77. (Pubitemid 36015920)
21. Chan V, Burgess JK, Ratoff JC, O'Connor BJ, Greenough A, Lee TH et al. Extracellular matrix regulates enhanced eotaxin expression in asthmatic airway smooth muscle cells. Am J Respir Crit Care Med 2006 174 : 379 385. (Pubitemid 44223117)
22. Johnson PR, Burgess JK, Underwood PA, Au W, Poniris MH, Tamm M et al. Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autocrine mechanism. J Allergy Clin Immunol 2004 113 : 690 696. (Pubitemid 38530425)
23. Brightling CE, Ammit AJ, Kaur D, Black JL, Wardlaw AJ, Hughes JM et al. The CXCL10/CXCR3 axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit Care Med 2005 171 : 1103 1108. (Pubitemid 40663721)
24. Cristofalo VJ, Allen RG, Pignolo RJ, Martin BG, Beck JC. Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation. Proc Nat Acad Sci USA 1998 95 : 10614 10619. (Pubitemid 28413116)
25. Lazaar AL, Amrani Y, Hsu J, Panettieri RA, Fanslow WC, Albelda SM et al. CD40-mediated signal transduction in human airway smooth muscle. J Immunol 1998 161 : 3120 3127. (Pubitemid 28425740)
26. Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 2000 351 : 95 105.
27. Yoshida S, Hashimoto S, Nakayama T, Kobayashi T, Koizumi A, Horie T. Elevation of serum soluble tumour necrosis factor (TNF) receptor and IL-1 receptor antagonist levels in bronchial asthma. Clin Exp Immunol 1996 106 : 73 78. (Pubitemid 26329382)
28. Xanthoulea S, Pasparakis M, Kousteni S, Brakebusch C, Wallach D, Bauer J et al. Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases. J Exp Med 2004 200 : 367 376. (Pubitemid 39031255)
29. Begueret H, Berger P, Vernejoux JM, Dubuisson L, Marthan R, Tunon-de-Lara JM. Inflammation of bronchial smooth muscle in allergic asthma. Thorax 2007 62 : 8 15. (Pubitemid 46101760)