Identification by hydrogen/deuterium exchange of structural changes in tyrosine hydroxylase associated with regulation

Biochemistry

Volumn 48, Issue 22, 2009, Pages 4972-4979

  Wang, Shanzhi ^a   Sura, Giri R ^a   Dangott, Lawrence J ^a   Fitzpatrick, Paul F ^a,b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b University of Texas Health Science Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; CATALYTIC DOMAINS; HYDROGEN/DEUTERIUM EXCHANGE; N-TERMINAL; OPEN CONFORMATION; ORDERS OF MAGNITUDE; PEPTIDE BONDS; REGULATORY DOMAIN; REVERSIBLE PHOSPHORYLATION; SERINE RESIDUES; STRUCTURAL CHANGE; TYROSINE HYDROXYLASE;

AMINES; AMINO ACIDS; BRAIN; CONFORMATIONS; DEUTERIUM; ENZYMES; HORMONES; LAWS AND LEGISLATION; MASS SPECTROMETRY;

PHOSPHORYLATION;

CATECHOLAMINE; DOPAMINE; PEPTIDE; SERINE; TYROSINE 3 MONOOXYGENASE;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DEUTERIUM HYDROGEN EXCHANGE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

ANIMALS; CATALYTIC DOMAIN; CATECHOLAMINES; CATTLE; DEUTERIUM; DEUTERIUM EXCHANGE MEASUREMENT; DOPAMINE; HYDROGEN; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTEIN BINDING; RATS; SERINE; TYROSINE 3-MONOOXYGENASE;

EID: 66649111062     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9004254     Document Type: Article

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