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Volumn 50, Issue 2, 2009, Pages 266-272

Mutational analysis of KRAS, BRAF, and TP53 genes of ovarian serous carcinomas in Korean women

Author keywords

Grade; Mutation; Ovary; Serous carcinoma

Indexed keywords

B RAF KINASE; K RAS PROTEIN; PROTEIN P53;

EID: 66549109076     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2009.50.2.266     Document Type: Article
Times cited : (13)

References (30)
  • 1
    • 33947184242 scopus 로고    scopus 로고
    • Alternate molecular genetic pathways in ovarian carcinomas of common histological types
    • Willner J, Wurz K, Allison KH, Galic V, Garcia RL, Goff BA, et al. Alternate molecular genetic pathways in ovarian carcinomas of common histological types. Hum Pathol 2007;38:607-13.
    • (2007) Hum Pathol , vol.38 , pp. 607-613
    • Willner, J.1    Wurz, K.2    Allison, K.H.3    Galic, V.4    Garcia, R.L.5    Goff, B.A.6
  • 3
    • 1942469352 scopus 로고    scopus 로고
    • Ovarian tumorigenesis: A proposed model based on morphological and molecular genetic analysis
    • Shih IeM, Kurman RJ. Ovarian tumorigenesis: a proposed model based on morphological and molecular genetic analysis. Am J Pathol 2004;164:1511-8.
    • (2004) Am J Pathol , vol.164 , pp. 1511-1518
    • Shih, I.M.1    Kurman, R.J.2
  • 4
    • 0037454224 scopus 로고    scopus 로고
    • Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma
    • Singer G, Oldt R 3rd, Cohen Y, Wang BG, Sidransky D, Kurman RJ, et al. Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. J Natl Cancer Inst 2003;95:484-6.
    • (2003) J Natl Cancer Inst , vol.95 , pp. 484-486
    • Singer, G.1    Oldt 3rd, R.2    Cohen, Y.3    Wang, B.G.4    Sidransky, D.5    Kurman, R.J.6
  • 5
    • 1442274808 scopus 로고    scopus 로고
    • p38 MAP kinase: A convergence point in cancer therapy
    • Olson JM, Hallahan AR. p38 MAP kinase: a convergence point in cancer therapy. Trends Mol Med 2004;10:125-9.
    • (2004) Trends Mol Med , vol.10 , pp. 125-129
    • Olson, J.M.1    Hallahan, A.R.2
  • 6
    • 0037222652 scopus 로고    scopus 로고
    • Absence of exon 15 BRAF germline mutations in familial melanoma
    • Lang J, Boxer M, MacKie R. Absence of exon 15 BRAF germline mutations in familial melanoma. Hum Mutat 2003;21:327-30.
    • (2003) Hum Mutat , vol.21 , pp. 327-330
    • Lang, J.1    Boxer, M.2    MacKie, R.3
  • 8
    • 0037379904 scopus 로고    scopus 로고
    • High prevalence of BRAF mutations in thyroid cancer: Genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
    • Kimura ET, Nikiforova MN, Zhu Z, Knauf JA, Nikiforov YE, Fagin JA. High prevalence of BRAF mutations in thyroid cancer: genetic evidence for constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res 2003;63:1454-7.
    • (2003) Cancer Res , vol.63 , pp. 1454-1457
    • Kimura, E.T.1    Nikiforova, M.N.2    Zhu, Z.3    Knauf, J.A.4    Nikiforov, Y.E.5    Fagin, J.A.6
  • 10
    • 13244256870 scopus 로고    scopus 로고
    • Origins and molecular pathology of ovarian cancer
    • Bell DA. Origins and molecular pathology of ovarian cancer. Mod Pathol 2005;18 Suppl 2:S19-32.
    • (2005) Mod Pathol , vol.18 , Issue.SUPPL. 2
    • Bell, D.A.1
  • 11
    • 27144519156 scopus 로고    scopus 로고
    • Molecular pathogenesis of ovarian borderline tumors: New insights and old challenges
    • Shih IeM, Kurman RJ. Molecular pathogenesis of ovarian borderline tumors: new insights and old challenges. Clin Cancer Res 2005;11: 7273-9.
    • (2005) Clin Cancer Res , vol.11 , pp. 7273-7279
    • Shih, I.M.1    Kurman, R.J.2
  • 12
    • 21444458657 scopus 로고    scopus 로고
    • Involvement of the ras genes in female genital tract cancer
    • Mammas IN, Zafiropoulos A, Spandidos DA. Involvement of the ras genes in female genital tract cancer. Int J Oncol 2005;26:1241-55.
    • (2005) Int J Oncol , vol.26 , pp. 1241-1255
    • Mammas, I.N.1    Zafiropoulos, A.2    Spandidos, D.A.3
  • 13
    • 12844251290 scopus 로고    scopus 로고
    • Patterns of p53 mutations separate ovarian serous borderline tumors and low-and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: A mutational analysis with immunohistochemical correlation
    • Singer G, Stöhr R, Cope L, Dehari R, Hartmann A, Cao DF, et al. Patterns of p53 mutations separate ovarian serous borderline tumors and low-and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation. Am J Surg Pathol 2005;29:218-24.
    • (2005) Am J Surg Pathol , vol.29 , pp. 218-224
    • Singer, G.1    Stöhr, R.2    Cope, L.3    Dehari, R.4    Hartmann, A.5    Cao, D.F.6
  • 15
    • 16444378374 scopus 로고    scopus 로고
    • Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations
    • Pohl G, Ho CL, Kurman RJ, Bristow R, Wang TL, Shih IeM. Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations. Cancer Res 2005;65:1994-2000.
    • (2005) Cancer Res , vol.65 , pp. 1994-2000
    • Pohl, G.1    Ho, C.L.2    Kurman, R.J.3    Bristow, R.4    Wang, T.L.5    Shih, I.M.6
  • 16
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, Harris CC. Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 1994;54:4855-78.
    • (1994) Cancer Res , vol.54 , pp. 4855-4878
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 18
    • 2642583203 scopus 로고    scopus 로고
    • A multistep model for ovarian tumorigenesis: The value of mutation analysis in the KRAS and BRAF genes
    • Russell SE, McCluggage WG. A multistep model for ovarian tumorigenesis: the value of mutation analysis in the KRAS and BRAF genes. J Pathol 2004;203:617-9.
    • (2004) J Pathol , vol.203 , pp. 617-619
    • Russell, S.E.1    McCluggage, W.G.2
  • 19
    • 0032030793 scopus 로고    scopus 로고
    • Toward the development of a universal grading system for ovarian epithelial carcinoma: Testing of a proposed system in a series of 461 patients with uniform treatment and follow-up
    • Shimizu Y, Kamoi S, Amada S, Akiyama F, Silverberg SG. Toward the development of a universal grading system for ovarian epithelial carcinoma: testing of a proposed system in a series of 461 patients with uniform treatment and follow-up. Cancer 1998;82:893-901.
    • (1998) Cancer , vol.82 , pp. 893-901
    • Shimizu, Y.1    Kamoi, S.2    Amada, S.3    Akiyama, F.4    Silverberg, S.G.5
  • 20
    • 0032127617 scopus 로고    scopus 로고
    • Toward the development of a universal grading system for ovarian epithelial carcinoma. I. Prognostic significance of histopathologic features--problems involved in the architectural grading system
    • Shimizu Y, Kamoi S, Amada S, Hasumi K, Akiyama F, Silverberg SG. Toward the development of a universal grading system for ovarian epithelial carcinoma. I. Prognostic significance of histopathologic features--problems involved in the architectural grading system. Gynecol Oncol 1998;70:2-12.
    • (1998) Gynecol Oncol , vol.70 , pp. 2-12
    • Shimizu, Y.1    Kamoi, S.2    Amada, S.3    Hasumi, K.4    Akiyama, F.5    Silverberg, S.G.6
  • 21
  • 24
    • 0030054309 scopus 로고    scopus 로고
    • Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer
    • McGuire WP, Hoskins WJ, Brady MF, Kucera PR, Partridge EE, Look KY, et al. Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer. N Engl J Med 1996;334:1-6.
    • (1996) N Engl J Med , vol.334 , pp. 1-6
    • McGuire, W.P.1    Hoskins, W.J.2    Brady, M.F.3    Kucera, P.R.4    Partridge, E.E.5    Look, K.Y.6
  • 25
    • 0033986363 scopus 로고    scopus 로고
    • Phase III randomized study of cisplatin versus paclitaxel versus cisplatin and paclitaxel in patients with suboptimal stage III or IV ovarian cancer: A gynecologic oncology group study
    • Muggia FM, Braly PS, Brady MF, Sutton G, Niemann TH, Lentz SL, et al. Phase III randomized study of cisplatin versus paclitaxel versus cisplatin and paclitaxel in patients with suboptimal stage III or IV ovarian cancer: a gynecologic oncology group study. J Clin Oncol 2000;18:106-15.
    • (2000) J Clin Oncol , vol.18 , pp. 106-115
    • Muggia, F.M.1    Braly, P.S.2    Brady, M.F.3    Sutton, G.4    Niemann, T.H.5    Lentz, S.L.6
  • 26
    • 41349119347 scopus 로고    scopus 로고
    • Plaxe SC. Epidemiology of low-grade serous ovarian cancer. Am J Obstet Gynecol 2008;198:459.e1-8; discussion 459.e8-9.
    • Plaxe SC. Epidemiology of low-grade serous ovarian cancer. Am J Obstet Gynecol 2008;198:459.e1-8; discussion 459.e8-9.
  • 27
    • 0036710512 scopus 로고    scopus 로고
    • The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network
    • Mayo LD, Donner DB. The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network. Trends Biochem Sci 2002;27:462-7.
    • (2002) Trends Biochem Sci , vol.27 , pp. 462-467
    • Mayo, L.D.1    Donner, D.B.2
  • 30
    • 41349100528 scopus 로고    scopus 로고
    • Pathogenesis of ovarian cancer: Lessons from morphology and molecular biology and their clinical implications
    • Kurman RJ, Shih IeM. Pathogenesis of ovarian cancer: lessons from morphology and molecular biology and their clinical implications. Int J Gynecol Pathol 2008;27:151-60.
    • (2008) Int J Gynecol Pathol , vol.27 , pp. 151-160
    • Kurman, R.J.1    Shih, I.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.