DAX-1 expression in human adrenocortical neoplasms: Implications for steroidogenesis

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 7, 1998, Pages 2597-2600

  Reincke, M ^a   Beuschlein, F ^b   Lalli, E ^c   Arlt, W ^b   Vay, S ^b   Sassonecorsi, P ^c   Allolio, B ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; MESSENGER RNA;

ADRENAL CORTEX TUMOR; ARTICLE; CORRELATION FUNCTION; GENE MUTATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEROIDOGENESIS; TISSUE DISTRIBUTION;

EID: 0031728429     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.83.7.5095     Document Type: Article

References (15)

1. Zanaria E, Muscatelli F, Bardoni B, et al. 1994. An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita. Nature 372: 635-41.
2. Muscatelli F, Strom TM, Walker AP, et al. 1994 Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism. Nature 372: 672-6.
3. Guo W, Burris TP, McCabe ERB. 1995. Expression of DAX-1, the gene responsible for X-linkd adrenal hypoplasia congenita and hypogonadotropic hypgonadism, in the hypothalamic-pituitary-adrenal/gonadal axis. Biochem Mol Med 56: 8-13.
4. Tamai KT, Monaco L, Alastalo T-P, Lalli E, Parvinen M, Sassone-Corsi P. 1996. Hormonal and developmental regulation of DAX-1 expression in sertoli cells. Mol Endocrinol 10: 1561-69.
5. Majdic G, Saundrs PTK. 1995. Differential pattern of expression of DAX-1 and SF-1 in the fetal rat testis. Endocrinology 137: 3586-89.
6. Zazopoulos E, Lalli E, Stocco DM, Sassone-Corsi P. 1997. DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis. Nature 390: 311-315.
7. Clark BJ, Wells J, King SR, Stocco DM. 1994 The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse leydig tumor cells. J Biol Chem 269: 28314-22.
8. Morohashi K, Honda S, Inomato Y, Handa H, Omura T. 1992. A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450s. J Biol Chem 267: 17913-17919.
9. Luo X, Ikeda Y, Parker KL. 1994 A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation. Cell 77: 481-90.
10. Sasano H, Shizawa S, Suzuki T, et al. 1995 Ad4BP in the human adrenal cortex and its disorders. J Clin Endocrinol Metab 80: 2378-80.
11. Lalli E, Bardoni B, Zazopoulos E, Wurtz J-M, Strohm TM, Moras D, Sassone-Corsi P. 1997. A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypolasia congenita. Mol Endocrinol 11: 1950-60.
12. Ikeda Y, Shen WH, Ingraham HA, Parker KL. 1994. Developmental expression of mouse SF-1, an essential regulator of steroid hydroxylases. Mol Endocrinol 8: 654-62.
13. Burris TP, Guo W, Le T, McCabe ER 1995 Identification of a putative steroidogenic factor-1 response element in the DAX-1 promoter. Biochem Biophys Res Comm 214: 576-81.
14. Yu RN, Ito M, Jameson JL. 1996 Transcriptional regulation of the mouse DAX-1 promoter by steroidogenic factor-1. The International Society of Endocrinology, San Francisco, Program & Abstracts, Vol. II, 798.
15. Ikeda Y, Swain A, Weber TJ, Hentges KE, Zanaria E, Lalli E, Tamai KT, Sassone-Corsi P, Lovell-Badge R, Camerino G, Parker KL. 1996 Steroidogenic factor 1 and DAX-1 colocalize in multiple cell lineages: Potential links in endocrine development. Mol Endocrinol 10: 1261-72.