Double sugar and phosphate backbone-constrained nucleotides: Synthesis, structure, stability, and their incorporation into oligodeoxynucleotides

Journal of Organic Chemistry

Volumn 74, Issue 9, 2009, Pages 3248-3265

  Zhou, Chuanzheng ^a   Plashkevych, Oleksandr ^a   Chattopadhyaya, Jyoti ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AB INITIO CALCULATIONS; ANTISENSE OLIGODEOXYNUCLEOTIDES; AQUEOUS AMMONIA; CHAIR CONFORMATIONS; DEPROTECTION; DNA STRANDS; EQUILIBRIUM CONCENTRATION; EQUILIBRIUM MIXTURES; HYDRAZINE HYDRATE; MALDI-TOF; OLIGODEOXYNUCLEOTIDES; PHOSPHATE BACKBONE; PHOSPHODIESTER; PHOSPHOTRIESTER; SOLID SUPPORTS; STRUCTURAL STUDIES; THERMAL DENATURATIONS;

AMMONIA; AUDIO FREQUENCY AMPLIFIERS; CHEMICAL REACTIVITY; CONFORMATIONS; HYDRATES; HYDRAZINE; ISOMERS; NUCLEIC ACIDS; NUCLEOTIDES; OLIGOMERS; PYROLYSIS; RNA; STEREOCHEMISTRY; SUGAR (SUCROSE); SUGARS; SYNTHESIS (CHEMICAL);

LOW NOISE AMPLIFIERS;

1,3,2 DIOXAPHOSPHORINANE DERIVATIVE; AMMONIA; ANTISENSE OLIGODEOXYNUCLEOTIDE; COMPLEMENTARY DNA; COMPLEMENTARY RNA; DIMER; DOUBLE STRANDED DNA; FLUORINE; HYDRAZINE; NUCLEOTIDE; PHOSPHATE; PYRIDINE; SUGAR;

AB INITIO CALCULATION; AQUEOUS SOLUTION; ARTICLE; CHEMICAL REACTION KINETICS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DENATURATION; DIASTEREOISOMER; EQUILIBRIUM CONSTANT; ISOMER; ISOMERIZATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE METABOLISM; STEREOCHEMISTRY;

BASE SEQUENCE; CARBOHYDRATES; CATALYSIS; CIRCULAR DICHROISM; DEOXYRIBONUCLEASES; DIMERIZATION; FLUORIDES; MAGNETIC RESONANCE SPECTROSCOPY; NUCLEIC ACID CONFORMATION; NUCLEIC ACID DENATURATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHATES; QUANTUM THEORY; RNA; STEREOISOMERISM; TRANSITION TEMPERATURE;

EID: 66449134243     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo900391n     Document Type: Article

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