Biphasic activation of PKBα/Akt in platelets: Evidence for stimulation both by phosphatidylinositol 3,4-bisphosphate, produced VIA A novel pathway, and by phosphatidylinositol 3,4,5-trisphosphate

Journal of Biological Chemistry

Volumn 273, Issue 19, 1998, Pages 11630-11637

  Banfić, Hrvoje ^a   Downes, C Peter ^b   Rittenhouse, Susan E ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALPAIN; FIBRINOGEN; GUANINE NUCLEOTIDE BINDING PROTEIN; INTEGRIN; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3,4 BISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE C; THROMBIN RECEPTOR; TRIPHOSPHOINOSITIDE; UNCLASSIFIED DRUG; AKT1 PROTEIN, HUMAN; BETA ADRENERGIC RECEPTOR KINASE; CALPEPTIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIPEPTIDE; ONCOPROTEIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3,4,5-TRIPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4-DIPHOSPHATE; POLYPHOSPHOINOSITIDE; PROTEIN SERINE THREONINE KINASE;

ARTICLE; DEPHOSPHORYLATION; ENZYME ACTIVITY; IMMUNOBLOTTING; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; CYTOSKELETON; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; METABOLISM; THROMBOCYTE;

BETA-ADRENERGIC RECEPTOR KINASE; BLOOD PLATELETS; CALCIUM; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOSKELETON; DIPEPTIDES; ENZYME ACTIVATION; FIBRINOGEN; GTP-BINDING PROTEINS; HUMANS; PHOSPHATIDYLINOSITOL PHOSPHATES; PLATELET ACTIVATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TETRADECANOYLPHORBOL ACETATE;

EID: 0032495874     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.19.11630     Document Type: Article

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