Effects of combined phosphorylation at Ser-617 and Ser-1179 in endothelial nitric-oxide synthase on EC50(Ca2+) values for calmodulin binding and enzyme activation

Journal of Biological Chemistry

Volumn 284, Issue 18, 2009, Pages 11892-11899

  Tran, Quang Kim ^a   Leonard, Jared ^a   Black, D J ^a   Nadeau, Owen W ^b   Boulatnikov, Igor G ^b   Persechini, Anthony ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL PROPERTIES; CALMODULIN BINDING; CONCENTRATION OF; CONTROL VALUES; COOPERATIVITY; CYTOCHROME C; ENZYME ACTIVATION; IN-CELL; NITRIC-OXIDE SYNTHASE; REDUCTASE ACTIVITY; SYNTHASE;

BIOCHEMISTRY; CALCIUM; ELECTRIC CONDUCTIVITY MEASUREMENT; ENZYMES; PHOSPHORYLATION; SELF ASSEMBLY;

ENDOTHELIAL CELLS;

AMINO ACID; CALCIUM ION; CALMODULIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; OXIDOREDUCTASE; PROTEIN KINASE B; SERINE; CALCIUM; CYTOCHROME REDUCTASE; NOS3 PROTEIN, HUMAN;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CELL ACTIVITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; ANIMAL; CATTLE; CHEMISTRY; GENETICS; METABOLISM; MISSENSE MUTATION; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; PHYSIOLOGY;

AMINO ACID SUBSTITUTION; ANIMALS; CALCIUM; CALMODULIN; CATTLE; CYTOCHROME REDUCTASES; HUMANS; MUTATION, MISSENSE; NITRIC OXIDE SYNTHASE TYPE III; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; STRESS, PHYSIOLOGICAL;

EID: 66449127225     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M806205200     Document Type: Article

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