Synthesis and cytotoxic activity of 5,6-heteroaromatically annulated pyridine-2,4-diamines

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 13, 2009, Pages 4406-4419

  Willemann, C ^a   Grunert R ^b   Bednarski, P J ^b   Troschutz R ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

Carbolines; Cytotoxicity; Heterocyclic compounds; Pyridinediamines

Indexed keywords

11 (4 METHOXYBENZYL) N9,N9 DIMETHYL 11H BENZO[G]PYRIDO[2,3 B]INDOLE 7,9 DIAMINE; ANNULENE DERIVATIVE; AROMATIC COMPOUND; DIAMINE DERIVATIVE; ELLIPTICINE; INDOLEAMINE; N2,N2 DIMETHYL 9H PYRIDO[2,3 B]INDOLE 2,4 DIAMINE; N2,N2 DIMETHYLBENZO[H]QUINOLINE 2,4 DIAMINE; N9,N9 DIMETHYL 11H BENZO[G]PYRIDO[2,3 B]INDOLE 7,9 DIAMINE; N9,N9,11 TRIMETHYL 11H BENZO[G]PYRIDO[2,3 B]INDOLE 7,9 DIAMINE; NAPHTHYRIDINE DERIVATIVE; PYRIDINE DERIVATIVE; PYRROLE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANNULATION REACTION; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DIAMINES; DRUG SCREENING ASSAYS, ANTITUMOR; ELLIPTICINES; HUMANS; NEOPLASMS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 66449094787     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.05.016     Document Type: Article

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