In vivo expansion of the mammary stem/progenitor cell population by xanthosine infusion

Experimental Biology and Medicine

Volumn 234, Issue 4, 2009, Pages 475-482

  Capuco, Anthony V ^a   Evock Clover, Christina M ^a   Minuti, Andrea ^b   Wood, David L ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b UNIVERSITÀ CATTOLICA DEL SACRO CUORE   (Italy)

Author keywords

Immortal DNA strands; Mammary development; Progenitor cells; Stem cells

Indexed keywords

BROXURIDINE; TELOMERASE; XANTHOSINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CELL; CELL EXPANSION; CELL POPULATION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; EPITHELIUM CELL; FEMALE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MAMMARY GLAND; NONHUMAN; STEM CELL;

ANIMALS; BROMODEOXYURIDINE; CATTLE; CELL PROLIFERATION; FEMALE; IMMUNOHISTOCHEMISTRY; MAMMARY GLANDS, ANIMAL; RIBONUCLEOSIDES; STEM CELLS;

ANIMALIA; BOVINAE;

EID: 66449093123     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0811-RM-320     Document Type: Article

References (50)

1. Jones PH, Watt FM. Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 73:713-724, 1993. (Pubitemid 23159010)
2. Cosentino L, Shaver-Walker P, Heddle JA. The relationships among stem cells, crypts, and villi in the small intestine of mice as determined by mutation tagging. Dev Dyn 207:420-428, 1996. (Pubitemid 26399230)
3. Fliedner TM. The role of blood stem cells in hematopoietic cell renewal. Stem Cells 16 Suppl 1:13-29, 1998. (Pubitemid 28524502)
4. Shackleton M, Vaillant F, Simpson KJ, Stingl J, Smyth GK, Asselin-Labat ML, Wu L, Lindeman GJ, Visvader JE. Generation of a functional mammary gland from a single stem cell. Nature 439:84-88, 2006. (Pubitemid 43053633)
5. Kordon EC, Smith GH. An entire functional mammary gland may comprise the progeny from a single cell. Development 125:1921-1930, 1998. (Pubitemid 28274378)
6. Chepko G, Smith GH. Mammary epithelial stem cells: our current understanding. J Mammary Gland Biol Neoplasia 4:35-52, 1999.
7. Smith GH. Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat 39:21-31, 1996. (Pubitemid 26136501)
8. Paguirigan A, Beebe DJ, Alexander CM. Simulating mouse mammary gland development: cell ageing and its relation to stem and progenitor activity. Cell Prolif 40:106-124, 2007. (Pubitemid 46103694)
9. Capuco AV, Ellis S. Bovine mammary progenitor cells: current concepts and future directions. J Mammary Gland Biol Neoplasia 10:5-15, 2005. (Pubitemid 40724018)
10. Capuco AV. Identification of putative bovine mammary epithelial stem cells by their retention of labeled DNA strands. Exp Biol Med (Maywood) 232:1381-1390, 2007. (Pubitemid 350014428)
11. Capuco AV, Ellis S, Wood DL, Akers RM, Garrett W. Postnatal mammary ductal growth: three-dimensional imaging of cell proliferation, effects of estrogen treatment, and expression of steroid receptors in prepubertal calves. Tissue Cell 34:143-154, 2002.
12. Potten CS, Owen G, Booth D. Intestinal stem cells protect their genome by selective segregation of template DNA strands. J Cell Sci 115:2381-2388, 2002. (Pubitemid 34752981)
13. Smith GH. Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands. Development 132:681-687, 2005. (Pubitemid 40352828)
14. Bickenbach JR. Identification and behavior of label-retaining cells in oral mucosa and skin. J Dent Res 60 Spec No C:1611-1620, 1981.
15. Morris RJ, Fischer SM, Slaga TJ. Evidence that the centrally and peripherally located cells in the murine epidermal proliferative unit are two distinct cell populations. J Invest Dermatol 84:277-281, 1985. (Pubitemid 15109221)
16. Stingl J, Eirew P, Ricketson I, Shackleton M, Vaillant F, Choi D, Li HI, Eaves CJ. Purification and unique properties of mammary epithelial stem cells. Nature 439:993-997, 2006. (Pubitemid 43292419)
17. Liu S, Ginestier C, Charafe-Jauffret E, Foco H, Kleer CG, Merajver SD, Dontu G, Wicha MS. BRCA1 regulates human mammary stem/progenitor cell fate. Proc Natl Acad Sci U S A 105:1680-1685, 2008.
18. Lindvall C, Evans NC, Zylstra CR, Li Y, Alexander CM, Williams BO. The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesis. J Biol Chem 281:35081-35087, 2006. (Pubitemid 46036547)
19. Dontu G, Abdallah WM, Foley JM, Jackson KW, Clarke MF, Kawamura MJ, Wicha MS. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev 17:1253-1270, 2003.
20. Sherley JL. Asymmetric cell kinetics genes: the key to expansion of adult stem cells in culture. Stem Cells 20:561-572, 2002. (Pubitemid 35463069)
21. Rambhatla L, Ram-Mohan S, Cheng JJ, Sherley JL. Immortal DNA strand cosegregation requires p53/IMPDH-dependent asymmetric self-renewal associated with adult stem cells. Cancer Res 65:3155-3161, 2005. (Pubitemid 40524596)
22. Sherley JL, Stadler PB, Johnson DR. Expression of the wild-type p53 antioncogene induces guanine nucleotide-dependent stem cell division kinetics. Proc Natl Acad Sci U S A 92:136-140, 1995.
23. Lee HS, Crane GG, Merok JR, Tunstead JR, Hatch NL, Panchalingam K, Powers MJ, Griffith LG, Sherley JL. Clonal expansion of adult rat hepatic stem cell lines by suppression of asymmetric cell kinetics (SACK). Biotechnol Bioeng 83:760-777, 2003. (Pubitemid 37039597)
24. Capuco AV, Wood DL, Baldwin R, McLeod K, Paape MJ. Mammary cell number, proliferation, and apoptosis during a bovine lactation: relation to milk production and effect of bST. J Dairy Sci 84:2177-2187, 2001. (Pubitemid 33614546)
25. Clarke RB, Anderson E, Howell A, Potten CS. Regulation of human breast epithelial stem cells. Cell Prolif 36 Suppl 1:45-58, 2003. (Pubitemid 37521843)
26. Booth BW, Smith GH. Estrogen receptor-alpha and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands. Breast Cancer Res 8:R49, 2006. (Pubitemid 44314777)
27. Conboy MJ, Karasov AO, Rando TA. High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. PLoS Biol 5:e102, 2007. (Pubitemid 46790401)
28. Rando TA. The immortal strand hypothesis: segregation and reconstruction. Cell 129:1239-1243, 2007. (Pubitemid 46962100)
29. Sherley JL. Guanine nucleotide biosynthesis is regulated by the cellular p53 concentration. J Biol Chem 266:24815-24828, 1991. (Pubitemid 21909014)
30. Armakolas A, Klar AJ. Cell type regulates selective segregation of mouse chromosome 7 DNA strands in mitosis. Science 311:1146-1149, 2006. (Pubitemid 43305952)
31. Meeker AK, Coffey DS. Telomerase: a promising marker of biological immortality of germ, stem, and cancer cells. A review. Biochemistry (Mosc) 62:1323-1331, 1997.
32. Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131:861-872, 2007. (Pubitemid 350138099)
33. Broccoli D, Godley IA, Donehower LA, Varmus HE, De Lange T. Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell. Mol Cell Biol 16:3765-3772, 1996. (Pubitemid 26199896)
34. Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43:405-413, 1985. (Pubitemid 16213265)
35. Gillis AJ, Schuller AP, Skordalakes E. Structure of the Tribolium castaneum telomerase catalytic subunit TERT. Nature 455:633-637, 2008.
36. Chepko G, Dickson RB. Ultrastructure of the putative stem cell niche in rat mammary epithelium. Tissue Cell 35:83-93, 2003. (Pubitemid 36625938)
37. Chepko G, Smith GH. Three division-competent, structurally-distinct cell populations contribute to murine mammary epithelial renewal. Tissue Cell 29:239-253, 1997. (Pubitemid 27197107)
38. Clarke RB, Spence K, Anderson E, Howell A, Okano H, Potten CS. A putative human breast stem cell population is enriched for steroid receptor-positive cells. Dev Biol 277:443-456, 2005. (Pubitemid 40022963)
39. Asselin-Labat ML, Shackleton M, Stingl J, Vaillant F, Forrest NC, Eaves CJ, Visvader JE, Lindeman GJ. Steroid hormone receptor status of mouse mammary stem cells. J Natl Cancer Inst 98:1011-1014, 2006. (Pubitemid 44288166)
40. Sleeman KE, Kendrick H, Ashworth A, Isacke CM, Smalley MJ. CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Res 8:R7, 2006. (Pubitemid 44644832)
41. Sleeman KE, Kendrick H, Robertson D, Isacke CM, Ashworth A, Smalley MJ. Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland. J Cell Biol 176:19-26, 2007. (Pubitemid 46041676)
42. Ginestier C, Hur MH, Charafe-Jauffret E, Monville F, Dutcher J, Brown M, Jacquemier J, Viens P, Kleer CG, Liu S, Schott A, Hayes D, Birnbaum D, Wicha MS, Dontu G. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell 1:555-567, 2007. (Pubitemid 350056407)
43. Zeps N, Bentel JM, Papadimitriou JM, D'Antuono MF, Dawkins HJS. Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth. Differentiation 62:221-226, 1998. (Pubitemid 28165705)
44. Anderson E, Clarke RB. Steroid receptors and cell cycle in normal mammary epithelium. J Mammary Gland Biol Neoplasia 9:3-13, 2004. (Pubitemid 39137493)
45. Akers RM, McFadden TB, Purup S, Vestergaard M, Sejrsen K, Capuco AV. Local IGF-I axis in peripubertal ruminant mammary development. J Mammary Gland Biol Neoplasia 5:43-51, 2000.
46. Bocchinfuso WP, Lindzey JK, Hewitt SC, Clark JA, Myers PH, Cooper R, Korach KS. Induction of mammary gland development in estrogen receptor-alpha knockout mice. Endocrinology 141:2982-2994, 2000. (Pubitemid 32250463)
47. Mallepell S, Krust A, Chambon P, Brisken C. Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland. Proc Natl Acad Sci U S A 103:2196-2201, 2006. (Pubitemid 43271646)
48. Li RW, Meyer MJ, Van Tassell CP, Sonstegard TS, Connor EE, Van Amburgh ME, Boisclair YR, Capuco AV. Identification of estrogen-responsive genes in the parenchyma and fat pad of the bovine mammary gland by microarray analysis. Physiol Genomics 27:42-53, 2006. (Pubitemid 44511824)
49. Lamarca HL, Rosen JM. Hormones and mammary cell fate - what will I become when I grow up? Endocrinology 149:4317-4321, 2008.
50. Dontu G, El-Ashry D, Wicha MS. Breast cancer, stem/progenitor cells and the estrogen receptor. Trends Endocrinol Metab 15:193-197, 2004. (Pubitemid 38833988)