Insulin promotes the association of heat shock protein 90 with the inositol 1,4,5-trisphosphate receptor to dampen its Ca2+ release activity

Endocrinology

Volumn 150, Issue 5, 2009, Pages 2190-2196

  Nguyen, Nathalie ^a   Francoeur, Nancy ^a   Chartrand, Valerie ^a   Klarskov, Klaus ^a   Guillemette, Gaetan ^a   Boulay, Guylain ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CARBACHOL; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INSULIN RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN TYROSINE KINASE; RECOMBINANT HUMAN INSULIN; BENZOQUINONE DERIVATIVE; CALCIUM; CSK PROTEIN, HUMAN; INSULIN; MACROCYCLIC LACTAM; ONCOPROTEIN; PROTEIN KINASE;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; CALCIUM SIGNALING; CELL CULTURE; DOWN REGULATION; DRUG EFFECT; METABOLISM; PHYSIOLOGY;

BENZOQUINONES; CALCIUM; CALCIUM SIGNALING; CARBACHOL; CELLS, CULTURED; DOWN-REGULATION; HSP90 HEAT-SHOCK PROTEINS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; INSULIN; LACTAMS, MACROCYCLIC; PROTEIN BINDING; PROTEIN KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS;

EID: 66449085995     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1167     Document Type: Article

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