Combined directed remote metalation-transition metal catalyzed cross coupling strategies: The total synthesis of the aglycones of the gilvocarcins V, M, and E and arnottin I

Journal of Organic Chemistry

Volumn 74, Issue 11, 2009, Pages 4080-4093

  James, Clint A ^a,b   Snieckus, Victor ^a,c  

^a UNIVERSITY OF WATERLOO   (Canada)

^b Research and Development   (Canada)

^c QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AGLYCONES; CARBAMOYL; CHEMICAL EQUATIONS; CROSS-COUPLING; EFFICIENT SYNTHESIS; GILVOCARCINS; JUGLONE; LATE STAGE; LESSONS LEARNED; METALATION; MIGRATION PROCESS; MIGRATION STRATEGY; NATURAL PRODUCTS; NATURALLY OCCURRING; PROTECTING GROUP; STILLE COUPLING; SUZUKI COUPLING REACTION; TOTAL SYNTHESIS; TRIFLATE; VINYL GROUP;

CHEMICAL BONDS; NAPHTHALENE; SUGAR (SUCROSE); TRANSITION METALS;

SYNTHESIS (CHEMICAL);

AGLYCONE; ARNOTTIN I; DEFUCOGILVOCARCIN E; DEFUCOGILVOCARCIN M; GILVOCARCIN V; JUGLONE; LITHIUM DERIVATIVE; N BUTYLLITHIUM; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; CATALYSIS; CATALYST; CHEMICAL REACTION; CROSS COUPLING REACTION; DIRECTED REMOTE METALLATION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STILLE REACTION; STRUCTURE ANALYSIS; SUZUKI REACTION;

BENZOPYRANS; BIOLOGICAL PRODUCTS; CATALYSIS; COUMARINS; GLYCOSIDES; TRANSITION ELEMENTS;

EID: 66249141970     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9001454     Document Type: Article

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