Dietary fish oil is antihypertrophic but does not enhance postischemic myocardial function in female mice

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 296, Issue 4, 2009, Pages

  Huggins, Catherine E ^a   Curl, Claire L ^a   Patel, Ruchi ^b   McLennan, Peter L ^c   Theiss, Mandy L ^c   Pedrazzini, Thierry ^d   Pepe, Salvatore ^a,e,f   Delbridge, Lea M D ^a,e  

^a Cardiac Phenomics Laboratory   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c UNIVERSITY OF WOLLONGONG   (Australia)

^d University of Lausanne Medical Center   (Switzerland)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

Ischemia reperfusion; Langendorff perfused hearts; polyunsaturated fatty acids

Indexed keywords

ESTROGEN; FISH OIL; MEMBRANE LIPID; OMEGA 3 FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; EX VIVO STUDY; FEMALE; HEART ARRHYTHMIA; HEART FUNCTION; HEART HYPERTROPHY; HEART MUSCLE ISCHEMIA; HEART PERFORMANCE; HEART PROTECTION; INCIDENCE; MOUSE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPERFUSION; TRANSGENIC MOUSE; WILD TYPE;

ANGIOTENSIN II; ANGIOTENSINOGEN; ANIMALS; ARRHYTHMIAS, CARDIAC; DIETARY FATS, UNSATURATED; DISEASE MODELS, ANIMAL; ESTROGENS; FEMALE; FISH OILS; GENETIC PREDISPOSITION TO DISEASE; HYPERTROPHY; MICE; MICE, TRANSGENIC; MYOCARDIAL ISCHEMIA; MYOCARDIUM; OVARIECTOMY; REPERFUSION INJURY;

EID: 66249123294     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01151.2008     Document Type: Article

References (49)

1. Abdukeyum GG, Owen AJ, McLennan PL. Dietary (n-3) long-chain polyunsaturated fatty acids inhibit ischemia and reperfusion arrhythmias and infarction in rat heart not enhanced by ischemic preconditioning. J Nutr 138: 1902-1909, 2008.
2. Bell JR, Porrello ER, Huggins CE, Harrap SB, Delbridge LM. The intrinsic resistance of female hearts to an ischemic insult is abrogated in primary cardiac hypertrophy.Am J Physiol Heart Circ Physiol 294: H1514-H1522, 2008.
3. Burr ML, Fehily AM, Gilbert JF, Rogers S, Holliday RM, Sweetnam PM, Elwood PC, Deadman NM. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART). Lancet 2: 757-761, 1989.
4. Coronel R, Wilms-Schopman FJ, Den Ruijter HM, Belterman CN, Schumacher CA, Opthof T, Hovenier R, Lemmens AG, Terpstra AH, Katan MB, Zock P. Dietary n-3 fatty acids promote arrhythmias during acute regional myocardial ischemia in isolated pig hearts. Cardiovasc Res 73: 386-394, 2007.
5. Cross HR, Lu L, Steenbergen C, Philipson KD, Murphy E. Overex- pression of the cardiac Na+/Ca2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice. Circ Res 83: 1215-1223, 1998.
6. 2+ channel modulation. Eur J Pharmacol 586: 288-292, 2008.
7. Curl CL, Wendt IR, Canny BJ, Kotsanas G. Effects of ovariectomy and 17 beta-oestradiol replacement on [Ca2+]i in female rat cardiac myocytes. Clin Exp Pharmacol Physiol 30: 489-494, 2003.
8. Delbridge LM, Morgan TO, Harris PJ. Effects of endothelin-1 on the contractility of cardiomyocytes from the spontaneously hypertensive rat. Clin Exp Pharmacol Physiol 22: 755-762, 1995.
9. Domenighetti AA, Wang Q, Egger M, Richards SM, Pedrazzini T, Delbridge LM. Angiotensin Il-mediated phenotypic cardiomyocyte remodeling leads to age-dependent cardiac dysfunction and failure. Hypertension 46: 426-432, 2005.
10. Du XJ, Fang L, Kiriazis H. Sex dimorphism in cardiac pathophysiology: experimental findings, hormonal mechanisms, and molecular mechanisms. Pharmacol Ther 111: 434 - 475, 2006.
11. Duda MK, O'Shea KM, Lei B, Barrows BR, Azimzadeh AM, McElfresh TE, Hoit BD, Kop WJ, Stanley WC. Dietary supplementation with omega-3 PUFA increases adiponectin and attenuates ventricular remodeling and dysfunction with pressure overload. Cardiovasc Res 76: 303-310, 2007.
12. Dumitrescu C, Narayan P, Efimov IR, Cheng Y, Radin MJ, McCune SA, Altschuld RA. Mechanical alternans and restitution in failing SHHF rat left ventricles. Am J Physiol Heart Circ Physiol 282: H1320-H1326, 2002.
13. Freer RJ, Pappano AJ, Peach MJ, Bing KT, McLean MJ, Vogel S, Sperelakis N. Mechanism for the positive inotropic effect of angiotensin II on isolated cardiac muscle. Circ Res 39: 178 -183, 1976.
14. Friehs I, del Nido PJ. Increased susceptibility of hypertrophied hearts to ischemic injury. Ann Thorac Surg 75: S678 -S684, 2003.
15. 2+ transient induced by angiotensin II in isolated adult rabbit ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol 360: 575-584, 1999.
16. GISSI-HF Investigators, Tavazzi L, Maggioni AP, Marchioli R, Bar- lera S, Franzosi MG, Latini R, Lucci D, Nicolosi GL, Porcu M, Tognoni G. Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial. Lancet 372: 1223-1230, 2008.
17. GISSI Prevenzione Investigators. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico. Lancet 354: 447-455, 1999.
18. Honen BN, Saint DA, Laver DR. Suppression of calcium sparks in rat ventricular myocytes and direct inhibition of sheep cardiac RyR channels by EPA, DHA and oleic acid. J Membr Biol 196: 95-103, 2003.
19. Huggins CE, Bell JR, Pepe S, Delbridge LM. Bench-marking ventricular arrhythmias in the mouse-revisiting the 'Lambeth Conventions' 20 years on. Heart Lung Circ 17: 445-450, 2008.
20. Huggins CE, Domenighetti AA, Pedrazzini T, Pepe S, Delbridge LM. Elevated intracardiac angiotensin II leads to cardiac hypertrophy and mechanical dysfunction in normotensive mice. J Renin Angiotensin Aldo- sterone Syst 4: 186-190, 2003.
21. Huggins CE, McLennan PL, Theiss ML, Pedrazzini T, Pepe S, Del- bridge LMD. Sex differences in murine myocardial membrane lipid composition modulate growth and postischemic arrhythmia (Abstract). Mol Cell Cardiol 42: S4, 2007.
22. Humphreys RA, Kane KA, Parratt JR. The influence of maturation and gender on the anti-arrhythmic effect of ischaemic preconditioning in rats. Basic Res Cardiol 94: 1-8, 1999.
23. Johnson MS, Moore RL, Brown DA. Sex differences in myocardial infarct size are abolished by sarcolemmal KATP channel blockade in rat. Am Physiol Heart Circ Physiol 290: H2644-H2647, 2006.
24. Kahan T, Bergfeldt L. Left ventricular hypertrophy in hypertension: its arrhythmogenic potential. Heart 91: 250-256, 2005.
25. Konhilas JP, Leinwand LA. The effects of biological sex and diet on the development of heart failure. Circulation 116: 2747-2759, 2007.
26. Korotkova M, Gabrielsson BG, Holmang A, Larsson BM, Hanson LA, Strandvik B. Gender-related long-term effects in adult rats by perinatal dietary ratio of n-6/n-3 fatty acids. Am Physiol Regul Integr Comp Physiol 288: R575-R579, 2005.
27. 2+ exchange in the heart from ovariectomized rats: role of protein kinase A. Am Physiol Cell Physiol 292: C1625-C1635, 2007.
28. Marra CA, de Alaniz MJ. Influence of testosterone administration on the biosynthesis of unsaturated fatty acids in male and female rats. Lipids 24: 014 -1019, 1989.
29. Matthan NR, Jordan H, Chung M, Lichtenstein AH, Lathrop DA, au J. A systematic review and meta-analysis of the impact of omega-3 fatty acids on selected arrhythmia outcomes in animal models. Metabolism 54: 1557-1565, 2005.
30. Mazzolai L, Nussberger J, Aubert JF, Brunner DB, Gabbiani G, Brunner HR, Pedrazzini T. Blood pressure-independent cardiac hypertrophy induced by locally activated renin-angiotensin system. Hypertension 31: 1324-1330, 1998.
31. McLennan PL. Relative effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on cardiac arrhythmias in rats. Am Clin Nutr 57: 207-212, 1993.
32. McLennan PL, Abeywardena MY. Membrane basis for fish oil effects on the heart: linking natural hibernators to prevention of human sudden cardiac death. Membr Biol 206: 85-102, 2005.
33. Meyer R, Linz KW, Surges R, Meinardus S, Vees J, Hoffmann A, Windholz O, Grohe C. Rapid modulation of L-type calcium current by acutely applied oestrogens in isolated cardiac myocytes from human, guinea-pig and rat. Exp Physiol 83: 305-321, 1998.
34. Mozaffarian D. Fish and n-3 fatty acids for the prevention of fatal coronary heart disease and sudden cardiac death. Am Clin Nutr 87: 1991S-1996S, 2008.
35. Nikolic I, Liu D, Bell JA, Collins J, Steenbergen C, Murphy E. Treatment with an estrogen receptor-beta-selective agonist is cardiopro- tective. Mol Cell Cardiol 42: 769 -780, 2007.
36. Olsson MC, Palmer BM, Leinwand LA, Moore RL. Gender and aging in a transgenic mouse model of hypertrophic cardiomyopathy. Am Physiol Heart Circ Physiol 280: H1136-H1144, 2001.
37. Owen AJ, Peter-Przyborowska BA, Hoy AJ, McLennan PL. Dietary fish oil dose- and time-response effects on cardiac phospholipid fatty acid composition. Lipids 39: 955-961, 2004.
38. Pedram A, Razandi M, Aitkenhead M, Levin ER. Estrogen inhibits cardio- myocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1. J Biol Chem 280: 26339-26348, 2005.
39. Pepe S, McLennan PL. Cardiac membrane fatty acid composition modulates myocardial oxygen consumption and postischemic recovery of contractile function. Circulation 105: 2303-2308, 2002.
40. Saito Y, Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Ish- ikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K. Effects of EPA on coronary artery disease in hypercholesterolemic patients with multiple risk factors: sub-analysis of primary prevention cases from the Japan EPA Lipid Intervention Study (JELIS). Atherosclerosis 200: 135-140, 2008.
41. Shimojo N, Jesmin S, Zaedi S, Maeda S, Soma M, Aonuma K, Yamaguchi I, Miyauchi T. Eicosapentaenoic acid prevents endothelin- 1-induced cardiomyocyte hypertrophy in vitro through the suppression of TGF- p 1 and phosphorylated JNK. Am J Physiol Heart Circ Physiol 291: H835-H845, 2006.
42. Siddiqui RA, Shaikh SR, Kovacs R, Stillwell W, Zaloga G. Inhibition of phenylephrine-induced cardiac hypertrophy by docosahexaenoic acid. J Cell Biochem 92: 1141-1159, 2004.
43. Skavdahl M, Steenbergen C, Clark J, Myers P, Demianenko T, Mao L, Rockman HA, Korach KS, Murphy E. Estrogen receptor-p mediates male-female differences in the development of pressure overload hypertrophy. Am J Physiol Heart Circ Physiol 288: H469-H476, 2005.
44. Stauffer BL, Konhilas JP, Luczak ED, Leinwand LA. Soy diet worsens heart disease in mice. J Clin Invest 116: 209 -216, 2006.
45. Takahashi R, Okumura K, Asai T, Hirai T, Murakami H, Murakami R, Numaguchi Y, Matsui H, Ito M, Murohara T. Dietary fish oil attenuates cardiac hypertrophy in lipotoxic cardiomyopathy due to systemic carnitine deficiency. Cardiovasc Res 68: 213-223, 2005.
46. Vila Petroff MG, Mattiazzi AR. Angiotensin II and cardiac excitation- contraction coupling: questions and controversies. Heart Lung Circ 10: 90-98, 2001.
47. 2+ currents by polyunsaturated fatty acids in adult and neonatal rat ventricular myocytes. Proc Natl Acad Sci USA 94: 4182-4187, 1997.
48. Xue B, Pamidimukkala J, Hay M. Sex differences in the development of angiotensin II-induced hypertension in conscious mice. Am J Physiol Heart Circ Physiol 288: H2177-H2184, 2005.
49. Yokoyama M, Origasa H, Matsuzaki M, Matsuzawa Y, Saito Y, Ishikawa Y, Oikawa S, Sasaki J, Hishida H, Itakura H, Kita T, Kitabatake A, Nakaya N, Sakata T, Shimada K, Shirato K. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet 369: 1090-1098, 2007.