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Volumn 75, Issue 11, 2009, Pages 3437-3446

Metabolic engineering of Saccharomyces cerevisiae for production of novel cyanophycins with an extended range of constituent amino acids

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL METHOD; ARGININOSUCCINATE LYASE; CITRULLINE; CYANOPHYCIN; EXTENDED RANGE; L-ASPARTIC ACID; METABOLIC ENGINEERING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE STRAINS; SYNECHOCYSTIS SP; SYNTHETASE;

EID: 66249115286     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.00383-09     Document Type: Article
Times cited : (47)

References (56)
  • 1
    • 0033714944 scopus 로고    scopus 로고
    • Molecular characterization of the cyanophycin synthetase from Synechocystis sp. strain PCC 6308
    • Aboulmagd, E., F. B. Oppermann-Sanio, and A. Steinbüchel. 2000. Molecular characterization of the cyanophycin synthetase from Synechocystis sp. strain PCC 6308. Arch. Microbiol. 174:297-306.
    • (2000) Arch. Microbiol. , vol.174 , pp. 297-306
    • Aboulmagd, E.1    Oppermann-Sanio, F.B.2    Steinbüchel, A.3
  • 2
    • 0035350831 scopus 로고    scopus 로고
    • Purification of Synechocystis sp. strain PCC 6308 cyanophycin synthetase and its characterization with respect to substrate and primer specificity
    • Aboulmagd, E., F. B. Oppermann-Sanio, and A. Steinbüchel. 2001. Purification of Synechocystis sp. strain PCC 6308 cyanophycin synthetase and its characterization with respect to substrate and primer specificity. Appl. Microbiol. Biotechnol. 67:2176-2182.
    • (2001) Appl. Microbiol. Biotechnol. , vol.67 , pp. 2176-2182
    • Aboulmagd, E.1    Oppermann-Sanio, F.B.2    Steinbüchel, A.3
  • 3
    • 0035668788 scopus 로고    scopus 로고
    • Heterologous expression of cyanophycin synthetase and cyanophycin synthesis in the industrial relevant bacteria corynebacterium glutamicum and Ralstonia eutropha and in Pseudomonas putida
    • DOI 10.1021/bm010075a
    • Aboulmagd, E., I. Voss, F. B. Oppermann-Sanio, and A. Steinbüchel. 2001. Heterologous expression of cyanophycin synthetase and cyanophycin synthesis in the industrial relevant bacteria Corynebacterium glutamicum and Ralstonia eutropha and in Pseudomonas putida. Biomacromolecules 2:1338-1342. (Pubitemid 34026917)
    • (2001) Biomacromolecules , vol.2 , Issue.4 , pp. 1338-1342
    • Aboulmagd, E.1    Voss, I.2    Oppermann-Sanio, F.B.3    Steinbuchel, A.4
  • 5
    • 54349098431 scopus 로고    scopus 로고
    • A cyanophycin synthetase from Thermosynechococcus elongatus BP-1 catalyzes primer-independent cyanophycin synthesis
    • Arai, T., and K. Kino. 2008. A cyanophycin synthetase from Thermosynechococcus elongatus BP-1 catalyzes primer-independent cyanophycin synthesis. Appl. Microbiol. Biotechnol. 81:69-78.
    • (2008) Appl. Microbiol. Biotechnol. , vol.81 , pp. 69-78
    • Arai, T.1    Kino, K.2
  • 6
    • 33745163242 scopus 로고    scopus 로고
    • Dipeptide synthesis by an aminopeptidase from Streptomyces septatus TH-2 and its application to synthesis of biologically active peptides
    • Arima, J., Y. Uesugi, M. Uraji, M. Iwabuchi, and T. Hatanaka. 2006. Dipeptide synthesis by an aminopeptidase from Streptomyces septatus TH-2 and its application to synthesis of biologically active peptides. Appl. Environ. Microbiol. 72:4225-4231.
    • (2006) Appl. Environ. Microbiol. , vol.72 , pp. 4225-4231
    • Arima, J.1    Uesugi, Y.2    Uraji, M.3    Iwabuchi, M.4    Hatanaka, T.5
  • 7
    • 0033850973 scopus 로고    scopus 로고
    • Biosynthesis of the cyanobacterial reserve polymer multi-L-arginyl-poly- L-aspartic acid (cyanophycin): Mechanism of the cyanophycin synthetase reaction studied with synthetic primers
    • Berg, H., K. Ziegler, K. Piotukh, K. Baier, W. Lockau, and R. Volkmer-Engert. 2000. Biosynthesis of the cyanobacterial reserve polymer multi-L-arginyl-poly-L-aspartic acid (cyanophycin): mechanism of the cyanophycin synthetase reaction studied with synthetic primers. Eur. J. Biochem. 267:5561-5570.
    • (2000) Eur. J. Biochem. , vol.267 , pp. 5561-5570
    • Berg, H.1    Ziegler, K.2    Piotukh, K.3    Baier, K.4    Lockau, W.5    Volkmer-Engert, R.6
  • 8
    • 0032579440 scopus 로고    scopus 로고
    • Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR-mediated gene disruption and other applications
    • Brachmann, C. B., A. Davies, G. J. Cost, E. Caputo, J. Li, P. Hieter, and J. D. Boeke. 1998. Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications. Yeast 14:115-132.
    • (1998) Yeast , vol.14 , pp. 115-132
    • Brachmann, C.B.1    Davies, A.2    Cost, G.J.3    Caputo, E.4    Li, J.5    Hieter, P.6    Boeke, J.D.7
  • 9
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 10
    • 0019148470 scopus 로고
    • Proline: An essential intermediate in the degradation of arginine in Saccharomyces cerevisiae
    • Brandriss, M. C., and B. Magasanik. 1980. Proline: an essential intermediate in the degradation of arginine in Saccharomyces cerevisiae. J. Bacteriol. 143:1403-1410.
    • (1980) J. Bacteriol. , vol.143 , pp. 1403-1410
    • Brandriss, M.C.1    Magasanik, B.2
  • 11
    • 0019519136 scopus 로고
    • Subcellular compartmentation in control of converging pathways for proline and arginine metabolism in Saccharomyces cerevisiae
    • Brandriss, M. C., and B. Magasanik. 1981. Subcellular compartmentation in control of converging pathways for proline and arginine metabolism in Saccharomyces cerevisiae. J. Bacteriol. 145:1359-1364. (Pubitemid 11097356)
    • (1981) Journal of Bacteriology , vol.145 , Issue.3 , pp. 1359-1364
    • Brandriss, M.C.1    Magasanik, B.2
  • 12
    • 0000182975 scopus 로고
    • XL1-Blue: A high efficiency plasmid transforming recA Escherichia coli strain with β-galactosidase selection
    • Bullock, W. O., J. M. Fernandez, and J. M. Stuart. 1987. XL1-Blue: a high efficiency plasmid transforming recA Escherichia coli strain with β-galactosidase selection. BioTechniques 5:376-379.
    • (1987) BioTechniques , vol.5 , pp. 376-379
    • Bullock, W.O.1    Fernandez, J.M.2    Stuart, J.M.3
  • 13
    • 33644930857 scopus 로고    scopus 로고
    • Optimization of cyanophycin production in recombinant strains of Pseudomonas putida and Ralstonia eutropha employing elementary mode analysis and statistical experimental design
    • Diniz, C. S., I. Voss, and A. Steinbüchel. 2006. Optimization of cyanophycin production in recombinant strains of Pseudomonas putida and Ralstonia eutropha employing elementary mode analysis and statistical experimental design. Biotechnol. Bioeng. 93:698-717.
    • (2006) Biotechnol. Bioeng. , vol.93 , pp. 698-717
    • Diniz, C.S.1    Voss, I.2    Steinbüchel, A.3
  • 14
    • 13544249631 scopus 로고    scopus 로고
    • Physiological conditions conducive to high cyanophycin content in biomass of Acinetobacter calcoaceticus strain ADP1
    • Elbahloul, Y., M. Krehenbrink, R. Reichelt, and A. Steinbüchel. 2005. Physiological conditions conducive to high cyanophycin content in biomass of Acinetobacter calcoaceticus strain ADP1. Appl. Environ. Microbiol. 71:858-866.
    • (2005) Appl. Environ. Microbiol. , vol.71 , pp. 858-866
    • Elbahloul, Y.1    Krehenbrink, M.2    Reichelt, R.3    Steinbüchel, A.4
  • 15
    • 33144470936 scopus 로고    scopus 로고
    • Engineering the genotype of Acinetobacter sp. strain ADP1 to enhance biosynthesis of cyanophycin
    • Elbahloul, Y., and A. Steinbüchel. 2006. Engineering the genotype of Acinetobacter sp. strain ADP1 to enhance biosynthesis of cyanophycin. Appl. Environ. Microbiol. 72:1410-1419.
    • (2006) Appl. Environ. Microbiol. , vol.72 , pp. 1410-1419
    • Elbahloul, Y.1    Steinbüchel, A.2
  • 16
    • 0035799392 scopus 로고    scopus 로고
    • A rapid and sensitive method for the analysis of cyanophycin
    • Erickson, N. A., N. H. Kolodny, and M. M. Allen. 2001. A rapid and sensitive method for the analysis of cyanophycin. Biochim. Biophys. Acta 1526:5-9.
    • (2001) Biochim. Biophys. Acta , vol.1526 , pp. 5-9
    • Erickson, N.A.1    Kolodny, N.H.2    Allen, M.M.3
  • 17
    • 0033118923 scopus 로고    scopus 로고
    • In Saccharomyces cerevisae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14p
    • DOI 10.1046/j.1432-1327.1999.00262.x
    • Feller, A., F. Ramos, A. Piérard, and E. Dubois. 1999. In Saccharomyces cerevisiae, feedback inhibition of homocitrate synthase isoenzymes by lysine modulates the activation of LYS gene expression by Lys14p. Eur. J. Biochem. 261:163-170. (Pubitemid 29166081)
    • (1999) European Journal of Biochemistry , vol.261 , Issue.1 , pp. 163-170
    • Feller, A.1    Ramos, F.2    Pierard, A.3    Dubois, E.4
  • 18
    • 0036304471 scopus 로고    scopus 로고
    • Technical-scale production of cyanophycin with recombinant strains of Escherichia coli
    • DOI 10.1128/AEM.68.7.3377-3384.2002
    • Frey, K. M., F. B. Oppermann-Sanio, H. Schmidt, and A. Steinbüchel. 2002. Technical-scale production of cyanophycin with recombinant strains of Escherichia coli. Appl. Environ. Microbiol. 68:3377-3384. (Pubitemid 34734035)
    • (2002) Applied and Environmental Microbiology , vol.68 , Issue.7 , pp. 3377-3384
    • Frey, K.M.1    Oppermann-Sanio, F.B.2    Schmidt, H.3    Steinbuchel, A.4
  • 19
    • 20144368166 scopus 로고    scopus 로고
    • Investigations on the solubility behavior of cyanophycin. Solubility of cyanophycin in solutions of simple inorganic salts
    • DOI 10.1021/bm049371o
    • Füser, G., and A. Steinbüchel. 2005. Investigations on the solubility behavior of cyanophycin: solubility of cyanophycin in solutions of simple inorganic salts. Biomacromolecules 6:1367-1374. (Pubitemid 40775052)
    • (2005) Biomacromolecules , vol.6 , Issue.3 , pp. 1367-1374
    • Fuser, G.1    Steinbuchel, A.2
  • 20
    • 18244428028 scopus 로고    scopus 로고
    • Lysine-overproducing mutants of Saccharomyces cerevisiae baker's yeast isolated in continuous culture
    • Gasent-Ramírez, J. M., and T. Benitez. 1997. Lysine-overproducing mutants of Saccharomyces cerevisiae baker's yeast isolated in continuous culture. Appl. Environ. Microbiol. 63:4800-4806.
    • (1997) Appl. Environ. Microbiol. , vol.63 , pp. 4800-4806
    • Gasent-Ramírez, J.M.1    Benitez, T.2
  • 21
    • 27644571150 scopus 로고    scopus 로고
    • Assessment of Hansenula polymorpha and Arxula adeninivorans-derived rDNA-targeting elements for the design of Arxula adeninivorans expression vectors
    • DOI 10.1016/j.femsyr.2005.07.005, PII S1567135605001170
    • Gellissen, G., G. Kunze, C. Gaillardin, J. M. Cregg, E. Berardi, M. Veenhuis, and I. van der Klei. 2005. New yeast expression platforms based on methylotrophic Hansenula polymorpha and Pichia pastoris and on dimorphic Arxula adeninivorans and Yarrowia lipolytica: a comparison. FEMS Yeast Res. 5:1079-1096. (Pubitemid 41564058)
    • (2005) FEMS Yeast Research , vol.5 , Issue.11 , pp. 1047-1054
    • Steinborn, G.1    Gellissen, G.2    Kunze, G.3
  • 22
    • 0036135278 scopus 로고    scopus 로고
    • Molecular characterization of a thermostable cyanophycin synthetase from the thermophylic cyanobacterium Synechococcus sp. MA19 and in vitro synthesis of cyanophycin and related polyamides
    • Hai, T., F. B. Oppermann-Sanio, and A. Steinbüchel. 2002. Molecular characterization of a thermostable cyanophycin synthetase from the thermophylic cyanobacterium Synechococcus sp. MA19 and in vitro synthesis of cyanophycin and related polyamides. Appl. Environ. Microbiol. 68:93-101.
    • (2002) Appl. Environ. Microbiol. , vol.68 , pp. 93-101
    • Hai, T.1    Oppermann-Sanio, F.B.2    Steinbüchel, A.3
  • 23
    • 33845547991 scopus 로고    scopus 로고
    • Activation of cyanophycin synthetase of Nostoc ellipsosporum strain NE1 by truncation at the carboxyterminal region
    • Hai, T., K. M. Frey, and A. Steinbüchel. 2006. Activation of cyanophycin synthetase of Nostoc ellipsosporum strain NE1 by truncation at the carboxyterminal region. Appl. Microbiol. Biotechnol. 72:7652-7660.
    • (2006) Appl. Microbiol. Biotechnol. , vol.72 , pp. 7652-7660
    • Hai, T.1    Frey, K.M.2    Steinbüchel, A.3
  • 25
    • 0014349908 scopus 로고
    • 5-Methyltryptophan- resistant mutations linked with the arginine G marker in Escherichia coli
    • Hiraga, S., K. Ito, T. Matsuyama, H Ozaki, and T. Yura. 1968. 5-Methyltryptophan- resistant mutations linked with the arginine G marker in Escherichia coli. J. Bacteriol. 96:1880-1881.
    • (1968) J. Bacteriol. , vol.96 , pp. 1880-1881
    • Hiraga, S.1    Ito, K.2    Matsuyama, T.3    Ozaki, H.4    Yura, T.5
  • 27
    • 0020529962 scopus 로고
    • Transformation of intact yeast cells treated with alkali cations
    • Ito, H., Y. Fukura, K. Murata, and A. Timura. 1983. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 15:163-168.
    • (1983) J. Bacteriol. , vol.15 , pp. 163-168
    • Ito, H.1    Fukura, Y.2    Murata, K.3    Timura, A.4
  • 28
    • 0018131294 scopus 로고
    • Arginine metabolism in Saccharomyces cerevisiae: Subcellular localization of the enzymes
    • Jauniaux, J.-C., L. A. Urrestarazu, and J.-M. Wiame. 1978. Arginine metabolism in Saccharomyces cerevisiae: subcellular localization of the enzymes. J. Bacteriol. 133:1096-1107.
    • (1978) J. Bacteriol. , vol.133 , pp. 1096-1107
    • Jauniaux, J.-C.1    Urrestarazu, L.A.2    Wiame, J.-M.3
  • 29
    • 34248342121 scopus 로고    scopus 로고
    • Polyasparaginic acid homopolymers and copolymers, biotechnical production and use thereof
    • Jan. U.S. patent 6,180,752
    • Joentgen, W., T. Groth, A. Steinbüchel, T. Hai, and F. B. Oppermann. Jan. 2001. Polyasparaginic acid homopolymers and copolymers, biotechnical production and use thereof. U.S. patent 6,180,752.
    • (2001)
    • Joentgen, W.1    Groth, T.2    Steinbüchel, A.3    Hai, T.4    Oppermann, F.B.5
  • 32
    • 0036236197 scopus 로고    scopus 로고
    • Evaluation of non-cyanobacterial genome sequences for occurrence of genes encoding proteins homologous to cyanophycin synthetase and cloning of an active cyanophycin synthetase from Acinetobacter sp. strain DSM 587
    • DOI 10.1007/s00203-001-0396-9
    • Krehenbrink, M., F. B. Oppermann-Sanio, and A. Steinbüchel. 2002. Evaluation of non-cyanobacterial genome sequences for occurrence of genes encoding proteins homologous to cyanophycin synthetase and cloning of an active cyanophycin synthetase from Acinetobacter sp. strain DSM 587. Arch. Microbiol. 177:371-380. (Pubitemid 34437955)
    • (2002) Archives of Microbiology , vol.177 , Issue.5 , pp. 371-380
    • Krehenbrink, M.1    Oppermann-Sanio, F.-B.2    Steinbuchel, A.3
  • 33
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 34
    • 0001673776 scopus 로고
    • Correspondence of cyanophycin granules with structured granules in Anabaena cylindrica
    • Lang, N. J., R. D. Simon, and C. P. Wolk. 1972. Correspondence of cyanophycin granules with structured granules in Anabaena cylindrica. Arch. Microbiol. 83:313-320.
    • (1972) Arch. Microbiol. , vol.83 , pp. 313-320
    • Lang, N.J.1    Simon, R.D.2    Wolk, C.P.3
  • 35
    • 0029623163 scopus 로고
    • Thermospray liquid chromatography/mass spectrometry study of diastereomeric isoindole derivatives of amino acids and amino acid amides
    • Leuken, R. G. J., A. L. L. Duchateau, and G. T. C. Kwakkenbos. 1995. Thermospray liquid chromatography/mass spectrometry study of diastereomeric isoindole derivatives of amino acids and amino acid amides. J. Pharm. Biomed. Anal. 13:1459-1464.
    • (1995) J. Pharm. Biomed. Anal. , vol.13 , pp. 1459-1464
    • Leuken, R.G.J.1    Duchateau, A.L.L.2    Kwakkenbos, G.T.C.3
  • 38
    • 0014659066 scopus 로고
    • Enzyme repression in the arginine pathway of Saccharomyces cerevisiae
    • Middelhoven, W. J. 1969. Enzyme repression in the arginine pathway of Saccharomyces cerevisiae. Antonie van Leeuwenhoek 35:215-226.
    • (1969) Antonie Van Leeuwenhoek , vol.35 , pp. 215-226
    • Middelhoven, W.J.1
  • 39
    • 0014717514 scopus 로고
    • Induction and repression of arginase and ornithine transaminase in baker's yeast
    • Middelhoven, W. J. 1970. Induction and repression of arginase and ornithine transaminase in baker's yeast. Antonie van Leeuwenhoek 36:1-19.
    • (1970) Antonie Van Leeuwenhoek , vol.36 , pp. 1-19
    • Middelhoven, W.J.1
  • 42
    • 27644549174 scopus 로고    scopus 로고
    • Production of cyanophycin, a suitable source for the biodegradable polymer polyaspartate, in transgenic plants
    • DOI 10.1111/j.1467-7652.2005.00122.x
    • Neumann, K., D. P. Stephan, K. Ziegler, M. Hühns, I. Broer, W. Lockau, and E. K. Pistorius. 2005. Production of cyanophycin, a suitable source for the biodegradable polymer polyaspartate, in transgenic plants. Plant Biotechnol. J. 3:249-258. (Pubitemid 41615428)
    • (2005) Plant Biotechnology Journal , vol.3 , Issue.2 , pp. 249-258
    • Neumann, K.1    Stephan, D.P.2    Ziegler, K.3    Huhns, M.4    Broer, I.5    Lockau, W.6    Pistorius, E.K.7
  • 43
    • 58149359424 scopus 로고    scopus 로고
    • Process for biotechnological production of β-dipeptides from cyanophycin at technical scale and its optimization
    • Sallam, A., A. Kast, S. Przybilla, T. Meiswinkel, and A. Steinbüchel. 2009. Process for biotechnological production of β-dipeptides from cyanophycin at technical scale and its optimization. Appl. Environ. Microbiol. 75:29-38.
    • (2009) Appl. Environ. Microbiol. , vol.75 , pp. 29-38
    • Sallam, A.1    Kast, A.2    Przybilla, S.3    Meiswinkel, T.4    Steinbüchel, A.5
  • 45
  • 46
    • 0031599328 scopus 로고    scopus 로고
    • Chemical synthesis of polyaspartates: A biodegradable alternative to currently used polycarboxylate homo- and copolymers
    • Schwamborn, M. 1998. Chemical synthesis of polyaspartates: a biodegradable alternative to currently used polycarboxylate homo- and copolymers. Polym. Degrad. Stabil. 59:39-45.
    • (1998) Polym. Degrad. Stabil. , vol.59 , pp. 39-45
    • Schwamborn, M.1
  • 47
    • 34547421751 scopus 로고    scopus 로고
    • Biomass in the manufacture of industrial products: The use of proteins and amino acids
    • Scott, E., F. Peter, and J. Sanders. 2007. Biomass in the manufacture of industrial products: the use of proteins and amino acids. Appl. Microbiol. Biotechnol. 75:751-762.
    • (2007) Appl. Microbiol. Biotechnol. , vol.75 , pp. 751-762
    • Scott, E.1    Peter, F.2    Sanders, J.3
  • 48
    • 0017263448 scopus 로고
    • The biosynthesis of multi-L-arginyl-poly(L-aspartic acid) in the filamentous cyanobacterium Anabaena cylindrica
    • Simon, R. D. 1976. The biosynthesis of multi-L-arginyl-poly(L-aspartic acid) in the filamentous cyanobacterium Anabaena cylindrica. Biochim. Biophys. Acta 422:407-418.
    • (1976) Biochim. Biophys. Acta , vol.422 , pp. 407-418
    • Simon, R.D.1
  • 49
    • 0016881981 scopus 로고
    • Determination of the structure of the novel polypeptide containing aspartic acid and arginine which is found in cyanobacteria
    • Simon, R. D., and P. Weathers. 1976. Determination of the structure of the novel polypeptide containing aspartic acid and arginine which is found in cyanobacteria. Biochim. Biophys. Acta 420:165-176.
    • (1976) Biochim. Biophys. Acta , vol.420 , pp. 165-176
    • Simon, R.D.1    Weathers, P.2
  • 50
    • 44949125733 scopus 로고    scopus 로고
    • Synthesis and accumulation of cyanophycin in transgenic strains of Saccharomyces cerevisiae
    • Steinle, A., F. B. Oppermann-Sanio, R. Reichelt, and A. Steinbüchel. 2008. Synthesis and accumulation of cyanophycin in transgenic strains of Saccharomyces cerevisiae. Appl. Environ. Microbiol. 74:3410-3418.
    • (2008) Appl. Environ. Microbiol. , vol.74 , pp. 3410-3418
    • Steinle, A.1    Oppermann-Sanio, F.B.2    Reichelt, R.3    Steinbüchel, A.4
  • 51
    • 84884611710 scopus 로고    scopus 로고
    • Cyanophycin synthetases
    • S. Lutz and U. T. Bornscheuer (ed.), Wiley-VCH Verlag GmbH & Co., Weinheim, Germany
    • Steinle, A., and A. Steinbüchel. 2008. Cyanophycin synthetases, p. 829-848. In S. Lutz and U. T. Bornscheuer (ed.), Protein engineering handbook. Wiley-VCH Verlag GmbH & Co., Weinheim, Germany.
    • (2008) Protein Engineering Handbook , pp. 829-848
    • Steinle, A.1    Steinbüchel, A.2
  • 52
    • 0033064557 scopus 로고    scopus 로고
    • 15N isotopic enrichment of cyanophycin synthesized by the cyanobacterium Synechocystis sp. strain PCC 6308
    • 15N isotopic enrichment of cyanophycin synthesized by the cyanobacterium Synechocystis sp. strain PCC 6308. Biochim. Biophys. Acta 1426:429-438.
    • (1999) Biochim. Biophys. Acta , vol.1426 , pp. 429-438
    • Suarez, C.1    Kohler, S.J.2    Allen, M.M.3    Kolodny, N.H.4
  • 53
    • 29544440779 scopus 로고    scopus 로고
    • Application of a KDPG-aldolase genedependent addiction system for enhanced production of cyanophycin in Ralstonia eutropha strain H16
    • Voss, I., and A. Steinbüchel. 2006. Application of a KDPG-aldolase genedependent addiction system for enhanced production of cyanophycin in Ralstonia eutropha strain H16. Metabol. Eng. 8:66-78.
    • (2006) Metabol. Eng. , vol.8 , pp. 66-78
    • Voss, I.1    Steinbüchel, A.2
  • 54
    • 0017669647 scopus 로고
    • Compartmentation of arginine biosynthesis in Saccharomyces cerevisiae
    • Wipf, B., and T. Leisinger. 1977. Compartmentation of arginine biosynthesis in Saccharomyces cerevisiae. FEMS Microbiol. Lett. 2:239-242.
    • (1977) FEMS Microbiol. Lett. , vol.2 , pp. 239-242
    • Wipf, B.1    Leisinger, T.2
  • 55
    • 0032523821 scopus 로고    scopus 로고
    • Molecular characterization of cyanophycin synthetase, the enzyme catalyzing the biosynthesis of the cyanobacterial reserve material multi-L- Arginyl-poly-L-aspartate (cyanophycin)
    • DOI 10.1046/j.1432-1327.1998.2540154.x
    • Ziegler, K., A. Diener, C. Herpin, R. Richter, R. Deutzmann, and W. Lockau. 1998. Molecular characterization of cyanophycin synthetase, the enzyme catalyzing the biosynthesis of the cyanobacterial reserve material multi-L-arginyl-poly-L-aspartate (cyanophycin). Eur. J. Biochem. 254:154-159. (Pubitemid 28255082)
    • (1998) European Journal of Biochemistry , vol.254 , Issue.1 , pp. 154-159
    • Ziegler, K.1    Diener, A.2    Herpin, C.3    Richter, R.4    Deutzmann, R.5    Lockau, W.6
  • 56
    • 0036560886 scopus 로고    scopus 로고
    • Cyanophycin synthetase-like enzymes of non-cyanobacterial eubacteria: Characterization of the polymer produced by a recombinant synthetase of Desulfitobacterium hafniense
    • Ziegler, K., R. Deutzmann, and W. Lockau. 2002. Cyanophycin synthetase-like enzymes of non-cyanobacterial eubacteria: characterization of the polymer produced by a recombinant synthetase of Desulfitobacterium hafniense. Z. Naturforsch. 57:522-529. (Pubitemid 34775947)
    • (2002) Zeitschrift fur Naturforschung - Section C Journal of Biosciences , vol.57 , Issue.5-6 , pp. 522-529
    • Ziegler, K.1    Deutzmann, R.2    Lockau, W.3


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